纳米羟基磷灰石及其复合材料对牙周膜细胞的影响

目前研究的纳米羟基磷灰石复合材料可分为3类：纳米羟基磷石灰天然复合材料、纳米羟基磷石灰半合成复合材料和纳米羟基磷石灰合成复合材料。文章按照纳米羟基磷灰石及其复合材料的分类介绍了纳米羟基磷灰石及其复合材料生物学特性，证实了纳米羟基磷灰石及其复合材料可以更好地促进人牙周膜细胞的生长，从而修复破坏的牙槽骨，建立牙周新附着。将纳米磷石灰及其复合材料应用于牙周膜细胞，将材料技术应用到牙周细胞的分化、牙骨的形成、牙齿的矫正及牙齿新附着的建立研究方面有着非常广阔的应用前景。     

高压氧治疗32例偏头痛

Background:Clinical manifestation of magraine is periodical onset of fluctuating headache caused by dysfunction of nerve vessel, which mechanism is still unclear.     

The rehabilitation effect of blood therapy after laser magnetization on patients with stroke

BACKGROUND:Therearelotsofmethodsforcuringstrokenowbuttheeffectoffunctionalrehabilitationisdifferent.Thispaperdealswiththerehabilitationeffectofbloodtherapyafterlasermag-netizationonpatientswithstroke.OBJECTIVE:Toinvestigatetherehabilitationeffectofbloodtherapyafterlasermagnetizationonpatientswithstroke.UNIT:DepartmentofInternalMedicine,CentralHospitalofJinzhouCitySUBJECTS:Therewere192patientsrecruitedfrom1998to2002provedbyCTorMRI,whichdiagnosisstandardaccordedwiththestandardof…     

促进脊髓损伤后神经再生的药物治疗

目的：对促进脊髓损伤后神经再生的药物及其作用机制进行分析和总结，为临床应用提供有力的支持。资料来源：应用计算机检索Pubmed1994—01／2005—12关于脊髓损伤药物治疗的相关文章。检索词“spinal cord injury，drugtreatment”并限定文章语种类为English。同时利用计算机检索中国期刊全文数据库1994—01／2005-12的相关文章，限定文章语言种类为中文，检索词“脊髓损伤，药物治疗”。资料选择：对资料进行初审，纳入标准：促进脊髓损伤后神经再生的药物及其作用机制、临床及实验推荐用量。排除标准：排除重复性研究。资料提炼：共收集到符合上述要求的文献48篇，排除30篇重复性研究。18篇符合纳入标准，其中6篇关于脊髓损伤药物治疗的研究，12篇关于脊髓损伤具体药物治疗的个案研究。资料综合：脊髓损伤后药物治疗包括两个阶段：急性及继发反应期，以及神经再生期。急性及继发反应期的药物治疗包括皮质类固醇类、神经节苷酯、内皮素受体拮抗剂、钙离子通道阻滞剂、兴奋性氨基酸拮抗剂等，神经再生期的药物治疗包括细胞生长因子、褪黑激素等。结论：对促进脊髓损伤后神经再生的药物及其作用机制的研究比较多，但仅少数几种应用于临床，大多数仍处也实验研究阶段，药物治疗脊髓损伤其前途是光明的。     

17β雌二醇对大鼠坐骨神经损伤的保护

目的：探讨预先应用17β雌二醇对大鼠坐骨神经损伤的治疗作用，为周围神经损伤的临床治疗提供实验依据。方法：实验于2004-10／2005-08在锦州医学院实验室完成。选择成年雄性SD大鼠54只，随机数字表法分为3组，假手术组18只，仅暴露不损伤神经；手术对照组18只，制作坐骨神经钳夹伤模型；17β雌二醇处理组18只，损伤前1周给予17β雌二醇（1mg／kg）腹腔注射，1次／d。余二组在手术前1周仅腹腔注射同体积的蓖麻油，1次／d。①于术后2，4，7，14，21，28d进行坐骨神经功能指数评定，坐骨神经功能指数-38．3（实验侧足印长度-正常侧足印长度）／正常侧足印长度＋109．5（实验侧足印宽度-正常侧足印宽度）／正常侧足印宽度＋13．3（实验侧足趾宽度-正常侧足趾宽度）／正常侧足趾宽度-8．8。坐骨神经功能指数以0为正常值。-100为神经完全离断指标。②术后7，14，28d各组取损伤近段坐骨神经甲苯胺蓝染色光镜下观察，醋酸铀和枸橼酸铅染色电镜下观察神经纤维超微结构。计算横断面单位面积的平均神经纤维个数和直径、轴突直径及髓鞘厚度。③术后7，14，21，28d各组大鼠取损伤近段坐骨神经进行S-100蛋白检测。结果：纳入动物54只，均进入结果分析。①假手术组术后2，28d坐骨神经功能指数值分别为-6．42和-5．71，差异无显著性意义。手术对照组和17β雌二醇处理组术后4，7，14，21d坐骨神经功能开始恢复，17β雌二醇处理组在术后21，28d坐骨神经功能指数值分别为-16．73和-16．14，而手术对照组在术后28d坐骨神经功能指数值为-16．32，可见17β雌二醇处理组大鼠功能恢复比手术对照组早1周左右。②光镜下观察术后14d17β雌二醇处理组损伤近段坐骨神经新生纤维较多，轴突直径较大且形状规则，纤维密度大、髓鞘较厚，明显高于手术对照组。术后28d手术对照组与17β雌二醇处理组变化基本一致，接近假手术组。③术后14d17β雌二醇处理组损伤近段坐骨神经电镜观察见大量新生神经纤维密集，许旺细胞包绕，轴突大小接近、形态均一，鞘内细胞器较多且清晰，明显优于手术对照组。术后28d手术对照组、17β雌二醇处理组新生神经纤维均基本成熟，差异不明显，已接近假手术组。④在周围神经损伤中S-100仅表达于许旺细胞中。术后14d 17β雌二醇处理组阳性显色深且范围宽，与手术对照组比较差异有显著性意义。术后21，28d手术对照组与17β雌二醇处理组又无明显差异。结论：17β雌二醇能加速大鼠坐骨神经损伤后功能的恢复以及神经纤维的再生修复。     

蝶窦内脑转移性小细胞癌一例

患者　女 ,4 5岁。因无诱因突然右眼视物模糊 10天入院。无头痛及内分泌紊乱症状。查体 :右眼视物模糊 ,无偏盲。头颅ＭＲＩ提示 :后组筛窦、蝶窦区可见不均匀等Ｔ1、Ｔ2信号 ,边缘不规则。病变累及颅内 ,压迫视神经 ,以右侧为著。增强呈不均匀强化。胸部平片 :可见胸廓对称 ,纹理清晰 ,纵隔无增宽 ,心脏大小形态正常 ,双肋膈角锐利。术前诊断为 :(1)垂体瘤 ;(2 )蝶窦内炎性肉芽肿。行经蝶肿瘤切除术。术中见蝶窦内肿物呈灰白色 ,质韧 ,无包膜 ,血供不丰富 ,未见明显肿瘤结节。行大部切除 ,瘤组织送病检 ,镜下可见大量嗜碱性小细胞弥漫性生…     

The rehabilitation effect of blood therapy after laser magnetization on patients with stroke

There are lots of methods for curing stroke now but the effect of function al rehabilitation is different.This paper deals with the rehabilitation effect of blood therapy after laser magnetization on patients with stroke.OBJECTIVE:To investigate the rehabilitation effect of blood therapy after laser magnetization on patients with stroke.UNIT:Department of Internal Medicine,Central Hospital of Jinzhou City.RESULTS:In treatment group,62 cases achieved recovery (64.6%),10cases achieved obvious effect(10.4%),18 cases achieved effect(18%) and 6 cases achieved no effect(6.3).The total effective rate was 93.8%;In control group,38 cases achieved recovery(39.6%),19 cases achieved obvious effect(20.0%),27 cases achieved effect(28.1%) cases achieved no effect(12.5%).The total effective rate was 87.5%.There were obvious differences between two groups(P&;lt;0.01).DISCUSSION:The blood therapy after laser magnetization can accelerate erythropoiesis,quickly improve saturation of blood oxygen and partial pressure of oxygen and improve state of anoxia of brain and factilitate recovery of cerebral function.     

激光磁化血液疗法对脑卒中患者的康复疗效

BACKGROUND:There are lots of methods for curing stroke now but the effect of functional rehabilitation is different.This paper deals with the rehabilitation effect of blood therapy after laser magnetization on patients with stroke.     

Therapeutic effect of hyperbaric oxygen on 32 cases of magraine

Background:Clinical manifestation of magraine is periodical onset of fluctuating headache caused by dysfunction of nerve-vessel,which mechanism is still unclear.Objective: To evaluate therapeutic effect of hyperbaric oxygen on magraine.Unit:Central Hospital of Jinzhou City.Subjects: According to diagnosis standards formulated by 1998 International Headache association,64 cases magraine in neural department of central hospital of Jinzhou city were randomly divided into 2 groups.Treatment group:12 males,20 females,aged 18-50 (mean:34)years old with disease course 4 months to 20 years (mean:4.5 years).Control group:13 males,19 females,aged 16-48(mean:33)years old with disease course 3 months to 18 years(mean:5 years).There was no obvious difference at sex,age,conditon between 2 groups.Intervention:Control group:Buflomedil was used,0.1g,once a day,venous injection and 14 days as a therapeutic course.Control group:On base of drug therapy,hyperbaric oxygen chamber therapy was adopted,raising pressure for 30-35min,stabilized pressure for 40 min,reducing pressure for 20 min,therapy pressure 0.2 MPa,once a day,10 days as a therapeutic course.Main prognosis index:Control:no relapse of headache when treating;Marked:Headache alleviated,continuing time shortened obviously,onset times reduced over 60%;Effective:Headache alleveated and continuing time shortened,onset times reduced over 50%;Ineffective:above standards couldn‘t be achieved.Result: Comparison of therapeutic effects between two groups see table 1.Conclusion: Both combination of hyperbaric oxygen with drug and simple drug therapy could reduce onset frequency of magraine,but combination therapy was more effective,and could shorten effect-producing time.     

Therapeutic effect of hyperbaric oxygen on 32 cases of magraine

Background:Clinicalmanifestationofmagraineisperiodicalonsetoffluctuatingheadachecausedbydysfunctionofnerve-vessel,whichmechanismisstillunclear.Objective:Toevaluatetherapeuticeffectofhyperbaricoxygenonmagraine.Unit:CentralHospitalofJinzhouCity.Subjects:Accordingtodiagnosisstandardsformulatedby1998InternationalHeadacheassociation,64casesmagraineinneuraldepartmentofcentralhospitalofJinzhoucitywererandomlydi-videdinto2groups.Treatmentgroup:12males,20females,aged18～50(mean:34)yearsoldwithdisea…