静息态功能磁共振成像分析原发性失眠患者大脑的小世界网络

Objective To explore the changes of small-world network properties in patients with primary insomnia based on resting-state functional magnetic resonance imaging (rs-fMRI). Methods The rs-MRI data and neurological scale data of 65 patients and 60 matched healthy controls were collected. The brain network was constructed using GRENTA software. SPSS software and network-based statistical analysis methods were used for statistical analysis. Results There was no significant difference between the two groups in terms of age, gender or education level (P>0.05), but PSQI, HAMA and HAMD scale scores differed significantly between the two groups (P<0.05). Both of the groups showed attributes of the small-world network. Compared with the control group, the patients with insomnia showed lower Cp, γ, Eloc, λ, connectivity, and σ of the small world network (P<0.05). Conclusion Patients with primary insomnia have lower global and local efficiencies than healthy individuals, and their ability to transmit information on the surface topology is impaired. Our data provide objective imaging evidences for the neuropathological mechanism of patients with primary insomnia.     

MRI在产前胎盘植入诊断的应用与进展

超声检查作为胎盘植入的检查方式有很多局限性, 如胎盘位置太深、羊水太少、孕妇过于肥胖等条件不利于超声准确评估。MRI越来越多地应用于胎盘植入诊断中, 尤其针对超声评估不佳的患者。近年来, MRI的快速扫描序列及功能成像, 如SSTSE、HASTE、DWI、MRS等在胎盘植入的诊断中发挥极大作用。MRI诊断胎盘植入的直接征象包括:子宫肌层变薄, 肌层不连续、胎盘子宫肌层分界不清。胎盘植入的间接征象包括:胎盘内的异质信号; T2WI像胎盘内低信号带; 胎盘内异常血管分布, 血管迂曲、粗大; 胎盘局部膨隆; 子宫局限性凸起; 邻近器官受侵等。异常胎盘的可能性随着胎盘侵袭的影像学特征数量的增加而增加, 并且与患者的危险因素如剖宫产、前置胎盘等因素相关。胎盘内暗带的出现是胎盘植入最强的佐证。本文就目前MRI在产前胎盘植入的应用与进展方面进行综述。      

MRI联合多层螺旋CT检查用于原发性肝癌介入治疗患者疗效评定的价值

  目的  评价MRI联合多层螺旋CT（MSCT）用于原发性肝癌介入治疗患者疗效评定中的临床价值。  方法  选取2019年5月~2021年5月130例原发性肝癌介入治疗患者作为研究对象,其中50例患者接受MSCT单一检查,40例患者接受MRI单一检查,40例患者接受MRI、MSCT联合检查,所有患者均以数字减影血管造影验证。以数字减影血管造影结果为金标准,比较MRI单一检查、MSCT单一检查以及联合检查患者介入治疗后残留病灶、复发病灶的敏感度、特异性及准确性,比较3种检查方式的病灶检出率。  结果  MRI、MSCT联合检查残留病灶的敏感度为89.3%、准确性为96.2%,高于MSCT单一检查（77.9%、91.4%）和MRI单一检查（83.5%、95.9%）（P < 0.05）;MRI、MSCT联合检查复发病灶的敏感度为88.6%、准确性为95.1%,高于MSCT单一检查（70.7%、91.4%）和MRI单一检查（74.2%、93.9%）（P < 0.05）。  结论  MRI联合MSCT检查用于原发性肝癌介入治疗患者疗效评定可更好的检出残留以及复发病灶,检出阳性病灶能力比单一影像学检查更高。