脾切除术治疗再生障碍性贫血20例

再生障碍性贫血是常见血液病,目前药物治疗尚不理想。用脾切除术治疗再障已有60多年的历史,各家报道效果不一,多数认为目前还是值得选用的一种治疗方法。现将我院1969～1975年脾切治疗再障20例小结如下:     

马利兰对慢性粒细胞白血病生存期的影响

本文对间歇大剂量马利兰和对照组治疗的29例慢性粒细胞白血病病人,进行随访分析。发现对照组生存曲线明显长于间歇大剂量马利兰组,并进行了Log—rank检验证实两组生存期相差显著,对两组治疗慢性粒细胞白血病的几个主要问题进行了讨论。     

急非淋白血病细胞转铁蛋白受体表达的临床意义

目的：了解解转铁蛋白受体（ＴｆＲ）在白血病细胞的表达情况及其临床意义。方法：对２０例正常及３２例急性非淋巴细胞白血病（ＡＮＬＬ）骨髓涂片用ＣＤ７１单克隆抗体免疫组化检测ＴｆＲ表达，并计算ＴｆＲ阳性细胞的百分率。结果：发现正常骨髓原早粒细胞ＴｆＲ阳性率为３７．５￣５３．５％（中位数４６．５％）；白血病细胞ＴｆＲ阳性率为０￣３１．６％（中位数１．２％），二者相差非常显著。治疗前白血病细胞ＴｆＲ阳性率高     

Remission of Acute Myelofibrosis after Vitamin D_3 Treatment: A Case Report

This article is to report the successful treatment of a case ofacute myelofibrosis(AMF) with vitamin D_3. A male, aged 52, was admittedbecaused of severe anemia (hemoglobin 19 g/L) for more than 6 months. Hehad been treated with various antianemic agents and fetal liver infusionelsewhere for more than 20 months without any effects. He had to live onrepeated blood transfusions. After 2-month-treatment with vitamin D_3injections, remarkable remission was obtained and his hemoglobin levelsteadily rose to 93 g/L without any more transfusion. In the15-month-followup, the patient did well. He could take care of his owndaily life and his hemoglobin level continued to rise to 114 g/L. The bonemarrow findings improved correspondingly. No side effect against vitaminD_3 was observed. This is the first AMF case treated successfully withvitamin D_3 reported in our country.     

35例恶性淋巴瘤血象,骨髓象分析

恶性淋巴瘤(ML)是原发于淋巴结或其它淋巴组织中的淋巴细胞和组织细胞发生恶性增生而引起的恶性肿瘤。近年来ML骨髓侵犯的临床研究日益受到重视,国外不少学者指出ML骨髓侵犯的研究不仅有助于对淋巴瘤扩散方式的探讨,而且对淋巴瘤的正确的     

急性白血病早期死亡因素分析

急性白血病(AL)随着治疗方法的进展,疗效有了明显提高,存活期也有所延长,但也有少部分病人在确诊后不久即早期死亡(早死)。对AL早死因素的认识及防止早死是提高AL疗效的重要一环。本文就本院近9年收治的85例成人AL中早期死亡的15例,对其早期死亡因素进行分析并提出初步预防意见供参考。     

骨髓转移癌所致骨髓痨性贫血6例报告

骨髓痨性贫血(Myelophthisic Anemia简写MA)是见于癌肿、肉瘤、肉芽肿、恶性淋巴瘤等细胞侵入骨髓,或其它生物、理化因素所致骨髓病损和(或)功能障碍所引起的一种贫血性疾病。因血象中出现或多或少的幼稚粒细胞和幼稚红细胞,故又称幼粒幼红细性胞贫血(Leuko-erythroblastic Anemia)。 癌肿伴有贫血或骨髓内转移并非少见,但并发MA,或以MA为初期表现者则很少,且后者常诊断困难。兹将我院收治的6例报告如下: