储存式自体血回输对前列腺癌患者根治术后复发影响的初步研究

目的:分析储存式自体血回输技术与前列腺癌(PCa)患者根治术后复发的相关性,探讨该技术在根治性前列腺切除术(RP)中的应用前景。方法:回顾性对比近5年在我院接受RP的随访病例45例,其中储存式自体血回输组(A组)20例,异体血输注组(B组)25例。定期随访tPSA、fPSA、直肠指捡及MRI检查等监测指标,判定肿瘤有无生化复发或转移,分析其组间差异。结果:A组T_(1a)～T_(1b)期8例、T_(2a)～T_(2c) 12例;B组T_(1a)～T_(1b)期14例、T_(2a)～T_(2c) 11例。A组自体输血量800 ml,B组输血量400～1 200 ml。两组手术时间、术中失血量、术后病理检查Gleason评分差异均无统计学意义(P0.05)。随访时间最短3个月,最长66个月;两组病例术后12个月、术后12～24个月、术后24～36个月、术后36～48个月、术后48个月以上tPSA无显著差异(P0.05)。结论:储存式自体血回收技术对于RP患者是安全的,并不增加肿瘤的复发率。     

还原型谷胱甘肽联合甘草酸二铵对腹部开放伤后海水浸泡犬肝功能损伤的治疗作用

Objective To investigate effect of reduced glutathione and diammonium glycyrrhizinate on the treatment of hepatic damage in experimental dogs following open abdominal injuries coupled with seawater immersion. Methods Twenty-four dogs with open abdominal injuries were randomly divided into 3 groups: the control group (given with simple observation after 1.5 h seawater immersion); the routine treatment group (given routine care and fluid transfusion after 1.5 h seawater immersion) ; the hepatic treatment group (given routine are, fluid transfusion and hepatic treatment as well, after 1.5 h seawater immersion). Each group consisted of 8 dogs. Blood samples were taken at different time points to measure total bilirubin (TB), alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), prothromin time (PT), endotoxin, tumor necrosis factor-α(TNF-α), interleukin-6 (IL-6), and pathological examination was also made at the same time. Results For the control group, contents of TB, ALT, AST and LDH increased significantly and survival time was less than 24 hours. Contents of TB, ALT, AST and LDH of the routine treatment group also increased significantly, but survival time of all the experimental animals was mere than 24 hours. Reduced glutathione and diammonium glycyrrhizinate could reduce the extent of lesion quite significantly 12～24 hours following open abdominal injuries. Conclusions Reduced glutathione and diammonium glycyrrhizinate seemed to have good effects on the treatment and prevention against hepatic damage induced by trauma coupled with seawater immersion. It could be used as a primary means for the treatment of such kind of hepatic damage.     

HPLC法测定小柴胡颗粒剂中黄芩苷的含量

目的 :建立小柴胡颗粒剂中黄芩苷的含量测定方法。方法 :采用反相高效液相色谱法。色谱柱 :Inertsil ODS- 3(5 μm,4 .6× 2 5 0 mm)柱 ;流动相 :甲醇 -水 -磷酸 (45∶ 5 5∶ 0 .2 ) ;检测波长 :315 nm。结果 :黄芩苷在 0 .2 4 2 9～ 1.2 14 4 μg/ml范围内呈现良好的线性关系 (r=0 .9999) ,回收率 10 0 .0 % ,RSD=0 .96 %。结论 :本法可用于测定小柴胡颗粒剂中黄芩苷的含量。     

广州清平药市动态

成都近期气温下降，药市除了滋补药品交易顺畅些外，其它交易清冷。大部分药材价格没有上升。重楼有药厂组织原料，价格上升，小重楼34—35元左右，大重楼38—42元，后市应有升幅。黄连降到40元以后，本期又反弹上升到43—45元。川芎本期价又降到小统货4．7元，大统货4．8—5元，但大货走动不畅。川白芷价稳在小统货4—4．2元，大统货4．5元左右，     

甲亢误诊为消化系统疾病8例分析

目的 分析甲亢误诊为消化系统疾病的原因和防止方法。方法 将我院就诊的8例误诊的甲亢患者分别进行甲状腺激素测定和详细的局部检查,并加以分析。结果 误诊病人甲状腺激素测定和局部检查后,给予抗甲状腺药物治疗后症状均消失或好转。结论 甲亢的临床表现具有多样性和全身性,极易误诊,应及时进行甲状腺功能检查,对甲状腺等组织进行详细的局部检查,防止误诊。     

狂犬病潜伏期25年一例报告

<正> 狂犬病潜伏期为10天至1年以上,一般为1～2月,文献中最长一例为19年。我院收治一例经病理证实的狂犬病患者,其潜伏期长达25年,现报告如下:病例男患,33岁,农民。因双下肢乏力,发热7天,恐水、吞咽困难5天,于1986年10月13日入院。该患入院前一周无明显诱因感双下肢无力、沉重,全身发热。2天后出现恐水、吞咽困难,恐惧不安,唾液增多,流涎不止。10月13日早起后行走困难、尿失禁,恐水、怕风加重,转送我院。病后无头痛及恶心、呕吐,神智清楚,未抽搐。因无法吞咽而3天未进饮食。既往史:平素健康。否认肝炎结核等病史。8周岁时曾被野外一狗咬破右手食指,当时伤口流血,但未做处置,也未注射狂     

听觉脑干电位对椎基底动脉缺血性眩晕的诊断

1椎-基底动脉系统解剖概述 椎动脉和基底动脉[1]及其它们的分支通常称为椎-基底动脉系统.内听动脉也称迷路动脉,系基底动脉下段向两侧发出的分支.但内听动脉大多数发自于小脑前下动脉.该动脉发出后绕过外展神经前部,走向桥延交界沟外侧,与面神经和位听神经一齐进入内听道,并在内听道内分成以下三支:     

吴银根治疗支气管扩张症的经验

吴银根为中国中医药学会理事、中国中西医结合呼吸专业委员会副主任委员、上海市中医呼吸专业委员会主任委员,已行医执教近40年。吴教授在继承前人经验的基础上,博采众长,辨证用药独识独创,治疗肺系疾病颇有建树,对支气管扩张症的临床诊治尤有心得。笔者现将其治疗支气管扩张症的经验介绍如下。 1 痰热肝火为标 1.1 痰热 风热犯肺或风寒袭肺,蕴结不解,郁而化热;或平素嗜酒太过、恣食辛辣煎炸厚味,酿湿蒸痰化热;或情志抑郁,化火生痰,痰火上扰,肺受邪热熏蒸所致。以咳嗽、吐大量黄脓痰,或痰中带血,血色鲜红,伴胸闷、发热、口干、尿赤、…