Pediatric intracranial aneurysms——clinical characteristics and therapeutic strategies

Objective To assess the radiological characteristics and therapeutic strategies of intracranial aneurysms in children. Methods From our dedicated neurovascular databank of patients, we reviewed 23 consecutive children who had 24 intracranial aneurysms. There were 14 boys and 9 girls with a mean age of 9.09 years ( range 1 - 14 years ). Results Intracranial aneurysms in children ≤ 14 years constituted 1.3% of all intracranial aneurysms. Internal Carotid artery (ICA) and middle cerebral artery (MCA) were the most frequent sites for aneurysms. About 58.3% of the aneurysms were complex, including dissecting, pseudoaneurysm, giant and fusiform aneurysm. 1/3 of all aneurysms were located in posterior circulation. Only 1 case had multiple aneurysms in this case series. Almost half of all cases presented with subarachnoid hemorrhage and others presented with mass effect. 14 cases underwent endovascular treatment. 4 patients received microsurgical therapy. 5 cases did not receive microsurgical or endovascular therapy, 2 of them whose aneurysms spontaneously thrombosed during follow up. One boy with left vertebral artery giant aneurysm died after endovascular therapy owing to gradual thrombosis in basilar artery. Another child had poor outcome because of rerupture of aneurysm before operation. Whereas the majority had a favorable outcome. Conclusions Intracranial aneurysms in children had many clinical and radiological characteristics different from those in adults : ( 1 ) remarkable male predominance; ( 2 ) ICA and MCA were the most common sites for aneurysms; (3) high incidence of large, traumatic, infectious, dissecting and fusiform aneurysms. (4)For pediatric intracranial aneurysms, both microsurgical approaches and endovascular treatment were effective. Endovaacular therapy was the best choice for complex aneurysms.     

从青霉属真菌Penicillium thiersii中分得具有抗昆虫作用的decaturine和oxalicine类似物

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浅谈血小板显微镜计数误差

血小板由骨髓中巨核细胞分化而来，在血液中则无前期细胞，它是人们止血过程中的重要因素，参与止血和凝血的许多环节。因此血小板计数是临床检验中血液分析的一项重要内容。其检验结果的准确性一直是检验工作者较为关注的问题，也是临床医生反映较大的问题之一。随着血液分析仪的不断普及，由于仪器设备原理上的限制和血小板易聚集，易破坏的特性，使血小板结果有偏差，对于血小板显著增高或者明显减少的标本必须由显微镜计数法去进行纠正。因此，显微镜计数方法尤显更为重要，现就我多年从事临床检验工作，多次使用该方法的过程中，发现影响显微镜计数血小板方法准确性有如下因素：     

心理因素对小学生脑力工作能力影响的研究

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试论精神科护理工作伦理道德

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脸色腰段椎间盘突出症21例临床分析

胸腰段椎间盘突出症罕见,约占椎间盘突出的0.6％～4％。随着CT及MRI的应用,其发病率有增加的趋势。因其发病率低,报道较少。但由于病变位于脊髓圆椎段,其发病较下腰段椎间盘突出有很大的特殊性,故有必要结合我院近年收治的21例对其作一回顾性分析。1 临床资料     

提高医疗管理水平,防范医疗事故发生

医疗纠纷和医疗事故最基本的防范措施就是严格执行规章制度和技术操作规范，每个岗位上的医务人员都应忠于职守，恪守职责，防止医疗漏洞，避免医疗事故和医疗纠纷的发生。现将笔者的体会介绍如下。     

社区健康教育的组织与实施

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