Experimental Observation on Osteogenetic Effects of Allogenic Decalcified Bone Matrix

This experiment was designed to evaluate the osteogenetic effects ofdifferent forms of allogenic decalcified bone matrix.39 rabbits were em-ployed and a bony defect of 1cm in length was made on the shaft of theulnas of the animals.They were divided into 4 groups.In the first group,the bony defects were filled with allogenic decalcified bone powder,in thesecond group,with decalcified bone blocks,in the third group,with unde-calcified bone blocks,and in the fourth group,nothing was filled into thebony defects.Roentgenological and histological studies were made regularly.It was found that after 8-10weeks,70-80% of the bony defects filledwith DBM showed firm union between the host bone and the graftedmaterial and no difference of the osteogenecity could be found between thetwo kinds of DBM,incomplete union occurred in the third group,andnonunion was seen in the fourth group.It is suggested that allogenic decalcified bone powder be used as a graftma-terial to fill up bony defects or cavities because it is easily preparedand used,has good plasticity,and can be stored in room temperature.     

脊髓损伤后的微血管变化实验性脊髓微血管造影研究

应用微血管造影技术对脊髓损伤后微血管变化进行了研究,所得结果是令人满意的。脊髓损伤后的微血管变化主要有以下几个方面:1.在外力直接作用的损伤区域,微血管改变最为明显;显影中断、变细或浅淡。血管边缘的毛刺征及钡剂外渗是致伤区血管的主要病变特征;2.髓内边缘动脉系统对压迫区周边白质部有吻合替代作用,脊髓中央区的坏死取决于髓中央动脉系统的血循变化。     

同种脱钙骨粉和骨块移植的实验观察

为证实不同形式的脱钙骨基质(DBM)及未脱钙骨的成骨作用进行了本实验。我们采用家兔39只,分为四组:(1)脱钙骨粉组;(2)脱钙骨块组;(3)未脱钙组;(4)空白组。将兔尺骨干造成1cm缺损后植入上述不同DBM及未脱钙骨,定期行X线及组织学观察。实验结果显示两种形式的DBM,在第8—10周标本的骨愈合率为70—80％,二者无明显差别。但未脱钙骨组在第8—10周标本只有部份连接。空白组在第10周无骨连接。以上结果表明DBM的成骨效应较未脱钙骨为优。骨粉制备简单,使用保存方便,可塑性强,作为骨移植材料填充骨腔是可行的。     

猪后肢钢珠致伤后的早期反应

用猪观察了高速投射物所致单侧后肢严重粉碎性骨折和软组织伤后的早期全身反应。结果可见,血液动力学、血气、胸片、血清T_3、T_4、果糖二磷酸醛缩酶、纤维结合蛋白、肺泡灌洗液蛋白含量及病理光、电镜检查均有不同程度的变化。死亡动物变化更为明显。本文还对伤后RDS与创伤指数-创伤严重度记分(ISS)的关系进行了讨论。并指出亚临床型RDS值得关注。     

小血管套叠“U”式缝合法的实验研究

本文介绍了一种小血管套叠“U”式缝合方法。在40根外径为0.5～1.0mm平均为0.6mm的大白鼠股动脉的套叠“U”式缝合中,其远期通畅率为100％。术后分别在7小时、3天、7天、15天和30天作了皮瓣成活、小血管造影、手术显微镜下解剖及组织学检查。文中对套叠“U”式缝合法与Lauritzen套叠法的优缺点作了比较。对其狭窄和愈合及缝合中应注意的问题亦作了讨论。认为套叠“U”式缝合法是一种通畅率高、操作简便、省时的小血管缝合法。     

吻合血管髂骨移植后微血管造影的观察

本文对12个吻合血管和8个不吻合血管的髂骨移植标本进行了微血管造影观察。11个吻合血管通畅的标本,移植骨内均有微血管分布,与宿主骨结合部的微血管主要来源于移植骨及骨膜,说明了移植物是存活的,并参与了和宿主骨的愈合。8个不吻合血管的髂骨移植标本中,4周以内的标本均未见微血管分布,8周以后的标本内见有少量周围软组织的微血管长入移植骨,说明传统骨移植的“爬行替代”较为缓慢。