六味地黄冲剂对肾阴虚病人血浆中锌铜含量的影响

肾阴虚病人血浆中锌、铜含量均较正常人血浆中锌,铜含量明显增高(P<0.01)。男女性别间本组未见差异。服用治疗肾阴虚药物六味地黄3种剂型后均使锌,铜含量明显降低(P<0.01),六味地黄冲剂与汤剂效果一致。     

有关发锌检测一些问题的探讨——3642名儿童发锌检测资料分析

本文通过对3642名儿童发锌检测资料分析，认为发锌确能反映儿童群体的锌营养状况，但一些儿童个体发锌值并不完全与其锌营养状况一致．因此判断儿童个体锌营养状况时除参考发锌值外，还应结合锌摄入量、生长发育和各种缺锌表现等指标综合判定。本文认为发锌正常值下限仍以<110ppm为宜，提出100～70ppm为体内锌营养下降或可能轻度缺锌，<70ppm为缺锌．     

口腔扁平苔癣浸润T细胞表达白细胞介素2受体的意义

为进一步探讨口腔扁平苔癣的发病机制，采用免疫组织化学ＰＡＰ法检测了２２例口腔扁平苔癣病损区浸润Ｔ细胞表达白细胞介素２受体的情况。结果有１５例扁平苔癣病损区浸润Ｔ细胞表面有白细胞介素２受体表达，其表达程度与病程及类型无明显关系（Ｐ＞０．０５）。结果提示，白细胞介素２受体的表达对Ｔ细胞在口腔扁平苔癣病损内聚集及局部免疫反应的启动、调节可能有重要影响。     

骨科病人并发下肢深静脉血栓形成40例分析

近年来 ,随着外伤性截瘫 ,下肢创伤病人的增多以及人工髋关节置换术的普遍应用 ,骨科病人并发下肢深静脉血栓形成 (L ower extremity deep venans thrombosis,DVT)的例数逐渐增多 ,此并发症的防治已备受关注 ,但国内相关报告较少。 1989年～ 1998年我科住院病人中发现 40例临床表现典型的 DVT,报告如下。临床资料一、一般资料　本组 40例中男性 2 2例 ,女性 18例 ;年龄 19～ 77岁 ,平均 49.6岁 ;左侧 2 4例 ,右侧 16例 ;混合型12例 ,中央型 2 3例 ,周围型 5例。临床表现 ,中央型主要为突发性下肢肿胀 ,浅表静脉显露或曲张 ,股三角区压痛 …     

微生物法考察威替米星注射液的生物学稳定性

目的:对威替米星注射液的生物学稳定性进行研究。方法:将威替米星注射液置于不同条件下考察其稳定性,采用微生物法和无菌检查法对放置样品的效价稳定性及是否长菌进行检测。结果:本品经高温试验(60.0±s2.0)℃10d,光照试验(4500lx)10d,加速试验[相对湿度(75±5)%,(40.0±2.0)℃]6mo,长期试验[相对湿度(60±5)%,(25.0±2.0)℃]12mo,其效价均未有明显变化,无菌检查亦符合规定。结论:本品在各放置条件下稳定性良好。     

心包内肺切除及部分左心房切除治疗肺癌

目的 探讨心包内肺及部分左心房切除治疗肺癌的手术指征和于术操作要点。方法 回顾性分析1998年8月2002年12月。对9例晚期肺癌行心包内肺切除合并部分左心房切除的临床资料。结果 全组无于术死亡，一年生存率为77．8％，最长生存49个月。结论对局部晚期肺癌行肺切除合并左心房部分切除能延长患者生存期，提高患者生活质量。     

CAG重复序列对中国脊髓小脑共济失调2型患者发病年龄的影响

目的:脊髓小脑共济失调2型(spinocerebellar ataxia type 2,SCA2)是世界上最常见的常染色体显性遗传的共济失调之一.多篇报道显示某些含polyQ基因的CAG重复序列可能影响SCA2患者的发病年龄(age at onset,AAO),但在中国SCA2患者中进行研究的较少.因此,本研究旨在探讨...     

强力霉素凝胶治疗大鼠口腔溃疡的实验研究

目的研究强力霉素对口腔溃疡的治疗作用,为临床用药提供指导。方法采用60%水醋酸酸蚀SD大鼠口腔颊黏膜建立大鼠溃疡模型。取36只造模成功大鼠随机分为3组,每组12只,分别给予高低剂量强力霉素及空白凝胶作局部治疗,分别于用药第2天、第4天、第6天每组处死4只大鼠,经过切取标本,石蜡包埋,制片,HE染色、麦氏染色和免疫组化染色后,于光镜下进行观察。结果用药后,强力霉素高低剂量组较对照组炎性渗出明显减少,充血情况明显减轻,胶原纤维降解、MMP-9的表达明显减少,溃疡愈合更快。结论强力霉素可能是通过抑制MMP-9的表达,减少胶原纤维的降解,促进口腔溃疡愈合。     

Clinical observation on Governor Vessel-unblocking and brain-refreshing scalp acupuncture for cerebral palsy complicated with intellectual disabilities

Objective

To observe the clinical efficacy of Governor Vessel-unblocking and brain-refreshing scalp acupuncture for cerebral palsy (CP) complicated with intellectual disabilities.

Methods

A total of 300 CP cases aged between 1 and 5 years were randomly allocated into a treatment group (n=150) and a control group (n=150). Patients in the treatment group were treated with Governor Vessel-unblocking and brainrefreshing scalp acupuncture combined with rehabilitation training, whereas patients in the control group received rehabilitation training alone. The Beijing Gesell developmental (Gesell) scale and gross motor function measure (GMFM) scale were used to assess the motor and intellectual development before and 3 months after the treatment. In addition, the head CT/MRI examination was applied to assess the brain nerve repair before and after the treatment.

Results

After the treatment, the total effective rate in the treatment group was 78.0%, versus 42.7% in the control group, showing a statistical significance (P<0.05). As for scores of five subscales in the Gesell scale, there were significant intra-group differences in the treatment group (all P<0.05); and the scores in the treatment group were significantly better than those in the control group (all P<0.05). As for scores of five dimensions in GMFM scale, there were significant intra-group differences in the treatment group (all P<0.05); and the scores in the treatment group were significantly better than those in the control group (all P<0.05). According to the head CT/MRI findings, the total effective rate was 73.3% in the treatment group, versus 62.0% in the control group, showing a statistical significance (P<0.05).

Conclusion

When used in combination with rehabilitative training, Governor Vessel-unblocking and brain-refreshing scalp acupuncture can significantly improve the clinical efficacy for cerebral palsy complicated with intellectual disabilities. It can also improve the patients’ motor function, intelligence and language ability.