Observation on clinical effect of tuina plus Western medication for functional dyspepsia due to liver qi stagnation and spleen deficiency

Objective

To observe the clinical effects of tuina plus Western medication for functional dyspepsia (FD) due to liver qi stagnation and spleen deficiency.

Methods

total of 72 patients in conformity with the inclusion criteria of FD were randomly divided into an observation group and a control group based upon the random number table, 36 cases in each group. The control group was treated with mosapride citrate dispersible tablets, and the observation group was treated with the same tablets plus tuina. Before the treatment and 4 weeks after the treatment, the clinical symptoms, quality of life (QOL) and depression severity were observed by the scale, and were followed up two months later after the treatment for assessment of the clinical effects.

Results

After the treatment and at the follow-up, the symptom scores of FD and the sores of Hamilton depression rating scale (HAMD) in both groups decreased, and the scores in Chinese version of quality of life questionnaire for functional digestive disorders (Chin-FDDQL) increased, with statistically significant differences in comparison with the same group before the treatment (all P<0.05). In comparison between the two groups at the same time point after the treatment, the scores of FD symptoms, HAMD and Chin-FDDQL were improved better in the observation group than those in the control group, with statistically significant differences (all P<0.05). The total effective rates at the follow-up were 91.7% in the observation group and 75.0% in the control group, without statistical difference between the two groups (P>0.05). The rate of clinical cure and remarkable effect was 66.7% in the observation group, higher than 41.7% in the control group, it is higher in the observation group than that in the control group, with a statistically significant difference between the two groups (P<0.05).

Conclusion

Tuina plus Western medication is precise in the therapeutic effects for FD due to liver qi stagnation and spleen deficiency and can effectively relieve clinical symptoms, elevate the QOL and alleviate depression severity of the patients. Moreover, it’s better than the treatment by Western medication alone in the long-term therapeutic effects.

     

中医药文化融入针灸的英文教学在涉外卓越班的实践探索

为了推动中医针灸在全球医学领域和国际社会的普及与传承,培育既精通专业技能又熟练掌握英语,并深植中医文化自信的高素质复合型人才变得至关重要。本文探讨了涉外针灸教学中文化元素关注不足的问题,并论述了中医药文化融入涉外针灸的英文教学的深远意义;笔者将中医药文化与英语的听、说、读、写及翻译五大能力相结合,形成了一种“五位一体”的综合教学模式,并将其应用于涉外针灸的研究生班和八年制卓越班,旨在全方位提高学生在针灸英语领域的专业能力和文化自信度,为涉外针灸人才的培养策略提供了有益的参考。     

电针不同神经节段穴位对大鼠胃运动异常模型胃内压的影响

目的探讨电针不同神经节段穴位对胃运动异常模型大鼠胃内压的调节作用及其效应的差异性。方法通过在大鼠胃内安置球囊的方法记录胃内压,观察电针足三里穴、内关穴、水沟穴、膻中穴、天枢穴对胃运动异常模型大鼠胃内压的影响。结果胃运动亢进和胃运动抑制模型大鼠针刺前后比较各组胃内压变化均有显著性差异(P<0.05);足三里穴组、天枢穴组与内关穴组、水沟穴组、膻中穴组比较胃内压变化有显著性差异(P<0.05);足三里穴组与天枢穴组比较胃内压变化差异无统计学意义(P>0.05)。结论电针不同神经节段穴位对胃运动异常大鼠胃内压均有双向调节作用,且该调节效应有差异性,足三里、天枢穴对胃运动异常大鼠胃内压的调节作用要优于内关、水沟、膻中穴。     

艾灸“足三里”对胃黏膜损伤大鼠内源性保护因子含量及相关蛋白表达的影响

目的观察艾灸"足三里"穴对孤束核损毁术后胃黏膜损伤大鼠内源性保护因子含量及相关蛋白的表达,探讨孤束核在艾灸保护胃黏膜损伤神经通路中的作用。方法按随机数字表法将48只健康SPF级SD大鼠分为4组:正常对照组,模型组,艾灸+模型组(艾灸组),艾灸+模型+孤束核损毁组(艾灸加孤束核损毁组),每组各12只。其中艾灸加孤束核损毁组予双侧孤束核损毁,护理3 d后,模型组和艾灸组大鼠均以无水乙醇(6 m L/kg)灌胃造模,并用阿司匹林混悬液(200 mg/kg)连续3 d灌胃以维持胃黏膜损伤,正常对照组用等量生理盐水灌胃,第4天进行艾灸"足三里"处理(正常对照组和模型组只绑不灸),每日2次,连续3 d。取血清及胃组织,计算胃黏膜损伤指数(UI),用ELISA法检测胃黏膜组织中表皮生长因子(EGF)、一氧化氮(NO)含量,用Western-blot法检测胃黏膜组织中抗凋亡蛋白(Bcl-2)、凋亡蛋白(Bax)的蛋白表达情况。结果与正常对照组比较,模型组胃黏膜损伤明显(P0.05);艾灸组UI较模型组下降(P0.05)。与模型组比,艾灸组血清、胃组织EGF、NO含量明显升高(均P0.05);艾灸加孤束核损毁组血清、胃组织EGF、NO含量较艾灸组低(均P0.05)。艾灸组和艾灸加孤束核损毁组Bcl-2蛋白表达较模型组有明显上升,而Bax表达明显下降(P0.05),细胞凋亡指数(AI)比值上升(P0.05)。结论艾灸足三里穴可调节机体内源性保护因子及蛋白的表达,保护胃黏膜,并受孤束核损毁的影响。证明孤束核是艾灸足三里穴产生胃黏膜保护效应信号传导通路中的重要调节部位。     

针刺对功能性便秘伴焦虑抑郁患者疗效的影响

目的:通过对功能性便秘患者焦虑、抑郁状态进行评估,探讨焦虑、抑郁与功能性便秘患者的关系及针刺对其疗效的影响,为临床诊治提供依据.方法:共观察43例患者,采用焦虑自评量表和抑郁自评量表于针刺治疗后第1、2、4周进行评估.并以针刺治疗后患者第1、2、4周的周排便总次数为针刺疗效的评价指标.比较焦虑或抑郁患者在功能性便秘患者所占的比例及心理障碍程度与排便频率的关系,以及针刺治疗功能性便秘与药物治疗的疗效差异.结果:焦虑、抑郁状态与功能性便秘患者的周总排便次数有相关性.但其排便的频率与焦虑、抑郁状态的程度无明显相关性.治疗结束后便秘患者的周排便次数均增加(P＜0.05),心理障碍者均得到改善.结论:心理因素与功能性肠病患者的周排便次数有相关性,针刺在治疗功能性便秘的同时可以改善患者的心理状态.     

Experimental study on the influence of pressing force and time on thermal effect of An-pressing manipulation

Objective

To observe the influence of pressing force and time on the thermal effect of An-pressing manipulation.

Methods

Eight healthy volunteers were recruited to receive An-pressing manipulation at Xinshu (BL 15) on the right side. The pressing force and time were both divided into five levels: the force described as extremely mild, mild, moderate, strong and extremely strong and time given by 2.5 min, 5.0 min, 7.5 min, 10.0 min and 15.0 min. The real-time change in local acupoint temperature as well as the change during 1.0-15.0 min after the manipulation were observed.

Results

Compared with the baseline data, the real-time changes in the temperature after An-pressing Xinshu (BL 15) on the right side with different levels of force (from mild to strong) were respectively (1.88±0.64) °C, (2.05±0.68) °C, (2.25±0.59) °C, (2.35±0.61) °C and (2.32±0.69) °C; the changes in 15.0 min after the manipulation were respectively (–0.11±0.11) °C, (0.03±0.14) °C, (0.59±0.58) °C, (1.38±0.70) °C and (2.09±0.98) °C. The real-time temperature changes after the manipulation for different durations (from short to long) were respectively (1.94±0.37) °C, (2.33±0.29) °C, (2.49±0.31) °C, (2.51±0.39) °C and (2.41±0.55) °C; the changes in 15.0 min after the manipulation were respectively (0.53±0.49) °C, (0.33±0.30) °C, (0.52±0.33) °C, (0.55±0.38) °C and (0.76±0.36) °C.

Conclusion

The thermal effect presented an increasing tendency with the extension of pressing time, and the temperature reached the top at 7.5 min; the thermal effect showed an increasing tendency with the rise of pressing force, and the temperature reached the top upon a moderate level of force. The pressing time can produce a greater influence on the real-time temperature than the pressing force; the pressing force can produce a greater influence on maintaining the temperature than the pressing time.