全文获取类型
收费全文 | 929篇 |
免费 | 41篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 35篇 |
妇产科学 | 7篇 |
基础医学 | 178篇 |
口腔科学 | 29篇 |
临床医学 | 65篇 |
内科学 | 125篇 |
皮肤病学 | 32篇 |
神经病学 | 68篇 |
特种医学 | 32篇 |
外科学 | 99篇 |
综合类 | 34篇 |
一般理论 | 1篇 |
预防医学 | 56篇 |
眼科学 | 27篇 |
药学 | 117篇 |
中国医学 | 3篇 |
肿瘤学 | 62篇 |
出版年
2023年 | 9篇 |
2022年 | 50篇 |
2021年 | 47篇 |
2020年 | 28篇 |
2019年 | 30篇 |
2018年 | 32篇 |
2017年 | 22篇 |
2016年 | 28篇 |
2015年 | 26篇 |
2014年 | 47篇 |
2013年 | 76篇 |
2012年 | 87篇 |
2011年 | 98篇 |
2010年 | 43篇 |
2009年 | 30篇 |
2008年 | 63篇 |
2007年 | 47篇 |
2006年 | 27篇 |
2005年 | 24篇 |
2004年 | 30篇 |
2003年 | 20篇 |
2002年 | 18篇 |
2001年 | 21篇 |
2000年 | 20篇 |
1999年 | 10篇 |
1998年 | 4篇 |
1997年 | 8篇 |
1996年 | 5篇 |
1995年 | 1篇 |
1994年 | 2篇 |
1993年 | 2篇 |
1992年 | 3篇 |
1991年 | 3篇 |
1990年 | 2篇 |
1989年 | 1篇 |
1988年 | 1篇 |
1987年 | 2篇 |
1986年 | 2篇 |
1985年 | 1篇 |
1984年 | 1篇 |
1979年 | 3篇 |
1974年 | 1篇 |
1973年 | 1篇 |
1966年 | 1篇 |
排序方式: 共有977条查询结果,搜索用时 15 毫秒
1.
2.
3.
Sharma R Mondal A Sahoo M Kakar A Shankar LR Khanna CM Chopra MK Soni NL 《The Journal of the Association of Physicians of India》1999,47(5):488-491
One hundred and forty eight subjects with euthyroid solitary thyroid nodules (STN) were taken up for radionuclide perfusion study. They were found to have a cold STN on 99mTc thyroid static scan. All had fine needle aspiration cytology (FNAC), and except for subjects with chronic lymphocytic thyroiditis, were subjected to surgery for tissue diagnosis by histopathology. The diagnostic findings in these patients of solitary thyroid nodules were correlated with the histopathology. Radionuclide perfusion study is considered useful to differentiate benign from malignant cold thyroid solitary nodules with high degree of sensitivity (95%) and specificity (87.9%). 相似文献
4.
5.
Catherine A. Hogan ChunHong Huang Malaya K. Sahoo Hannah Wang Becky Jiang Mamdouh Sibai Marisa Holubar Roshni Mathew James Zehnder Benjamin A. Pinsky 《Emerging infectious diseases》2021,27(2):632
We developed an assay that detects minus-strand RNA as a surrogate for actively replicating severe acute respiratory syndrome coronavirus 2. We detected minus-strand RNA in 41 persons with coronavirus disease up to 30 days after symptom onset. This assay might inform clinical decision-making about patient infectiousness. 相似文献
6.
Vineet Relhan Rima R. Sahay Anita M. Shete Pragya D. Yadav Bijaylaxmi Sahoo Deepak Y. Patil Suresh Kumar Kannan Sabarinath Premachandran Syamaladevi Lalit Dar Sreelekshmy Mohandas Priya Abraham 《Journal of medical virology》2023,95(1):e28249
We describe the clinical and demographic characteristics, virological follow-up, and management of five confirmed monkeypox cases from New Delhi, India without any international travel history. The viral load kinetics and viral clearance were estimated in oropharyngeal swabs (OPS), nasopharyngeal swabs (NPS), EDTA blood, serum, urine, and various lesion specimens on every fourth day of follow-up ranging from 5 to 24 post onset day (POD) of illness. All five cases presented with mild to moderate-grade intermittent fever, myalgia, and lesions on the genitals, groins, lower limb, trunk, and upper limb. Four cases had non-tender firm lymphadenopathy. No secondary complications or sexually transmitted infections were recorded in these cases except for the presence of viral hepatitis B infection marker hepatitis B virus surface antigen (HBsAg) in one case. All the cases were mild and had a good recovery. A higher viral load was detected in lesion fluid (POD 9), followed by lesion roof (POD 9), urine (POD 5), lesion base (POD 5), and OPS/NPS (POD 5). The monkeypox virus (MPXV) DNA was detected in clinical samples from 5th to 24th POD. These monkeypox cases without international travel history suggest the underdiagnosed monkeypox infection in the community. This emphasizes the need for active surveillance of MPXV in the high-risk population such as men having sex with men and female sex workers. 相似文献
7.
A 60-years old male patient presented with nodules and noduloulcerative lesions of mycosis fungoides (MF) of 6 months duration without any previous premycotic, patch or plaque stage. 相似文献
8.
9.
Gaur U Sahoo SK De TK Ghosh PC Maitra A Ghosh PK 《International journal of pharmaceutics》2000,202(1-2):1-10
The rapid clearance of circulating nanoparticles from the blood stream coupled with their high uptake by liver and spleen has thus far been overcome by reducing the particle size, and by making the particle surface hydrophilic with poloxamers and poloxamines. We have prepared hydrogel nanoparticles of polyvinylpyrrolidone of a size less than 100 nm diameter with precise size distribution. Since the inner cores of these particles are also hydrophilic, these particles are capable of encapsulating water-soluble compounds. Biodistribution of these particles shows practically negligible (<1%) uptake by the macrophages in liver and spleen, and approximately 5-10% of these particles remain in circulation even 8 h after i.v. injection. Increasing the surface hydrophobicity as well as particle size can increase the RES uptake of these particles. Because of longer residence in blood, the hydrogel nanoparticles have potential therapeutic applications particularly in cancer: the water-soluble cytotoxic agents encapsulated in these particles can be targeted to tumors while minimizing the likelihood of toxicity to reticuloendothelial system (RES). 相似文献
10.
Hemoglobinopathies such as β-thalassemia (β-thal) and sickle cell anemia (or Hb S [β6(A3)Glu→Val]) impose a major health burden in the Indian population. To determine the frequencies of the HBB gene mutations in eastern Indian populations and to compare with the available data, a comprehensive molecular analysis of the HBB gene was done in the normal Odisha State population. Using polymerase chain reaction (PCR), restriction fragment length polymorphism (RFLP), amplification refractory mutation system (ARMS) and DNA sequencing techniques, β-thal and sickle cell anemia mutations were characterized in 267 healthy individuals. Entire HBB gene sequencing showed 63 different mutations including 11 new ones. The predominant mutation HBB: c.9T?>?C was observed at a high frequency (19.57%) in the normal population. In the urban population of Odisha State, India, carrier frequency of hemoglobinopathies was found to be 18.48%, and for β-thal, the carrier rate was 14.13%, which is very high indeed. In the absence of a complete cure by any expensive treatment and drug administration, this information would be helpful for planning a population screening program and establishing prenatal diagnosis of β-thal in order to reduce the burden of such a genetic disease. 相似文献