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Clinical utility of multi‐detector cardiac computed tomography in structural heart interventions 下载免费PDF全文
Bo Xu Robert Gooley Sujith K Seneviratne Arthur Nasis 《Journal of Medical Imaging and Radiation Oncology》2016,60(3):299-305
In recent years, there have been major advances in structural interventional cardiology, which have revolutionized the practice of cardiology. Appropriate selection and follow‐up of patients undergoing these structural heart interventions is vital. Multi‐detector computed tomography (MDCT) has emerged as a key imaging modality in the peri‐procedural assessment of patients undergoing multiple structural cardiac interventions. The purpose of this review is to provide an evidence‐based clinical update on the roles of MDCT in both established and evolving structural heart interventions, including transcatheter aortic valve replacement (TAVR) and transcatheter mitral valve implantation (TMVI). The utility of MDCT in the peri‐procedural assessment of patients undergoing pulmonary vein isolation (PVI) for atrial fibrillation, cardiac resynchronization therapy (CRT) and left atrial appendage (LAA) closure will also be reviewed. 相似文献
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Ratnayake R Karunaratne V Ratnayake Bandara BM Kumar V MacLeod JK Simmonds P 《Journal of natural products》2001,64(3):376-378
The structures of the butenolides 1 and 2, isolated from the endemic plants Hortonia floribunda, H. angustifolia, and H. ovalifolia, collected in Sri Lanka, have been elucidated by spectroscopic analysis. These compounds exhibited potent mosquito larvicidal activity against the second instar larvae of Aedes aegypti. 相似文献
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Ahmad Mahamad Al-Yacouby Arwie Amri Mazli M. S. Liew R. M. Chandima Ratnayake Samindi M. K. Samarakoon 《Materials》2022,15(13)
Steel plates with openings are among the important ship structural components used in the ship’s hull to withstand the hydrostatic forces of the ocean, which cause sagging and hogging moments at the ship’s bottom. The existence of openings on plates can cause structural rupture, stress concentration and a decrease in ultimate strength. This research is aimed at investigating the influence of selected parameters on the ultimate capacity of steel plates with rectangular holes subjected to axial stress, using ANSYS finite element analysis (FEA) under its non-linear static structural programme. The main parameters investigated in this paper are the plate thickness, opening aspect ratio, number of openings, position of openings, and the boundary condition of the plate. The influence of these parameters on the stress of plates and their deformation was evaluated. The comparison of the numerical simulation with the well-established analytical method using the Navier solution and Roark’s Formulas showed a good agreement. 相似文献
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Atukorallaya Devi Sewvandini Atukorala Ravindra Kumar Ratnayake 《Anatomical record (Hoboken, N.J. : 2007)》2021,304(8):1650-1660
Human cleft lip and/or palate (CLP) are immediately recognizable congenital abnormalities of the face. Lip and palate develop from facial primordia through the coordinated activities of ectodermal epithelium and neural crest cells (NCCs) derived from ectomesenchyme tissue. Subtle changes in the regulatory mechanisms of NCC or ectodermal epithelial cells can result in CLP. Genetic and environmental contributions or a combination of both play a significant role in the progression of CLP. Model organisms provide us with a wealth of information in understanding the pathophysiology and genetic etiology of this complex disease. Small teleost, zebrafish (Danio rerio) is one of the popular model in craniofacial developmental biology. The short generation time and large number of optically transparent, easily manipulated embryos increase the value of zebrafish to identify novel candidate genes and gene regulatory networks underlying craniofacial development. In addition, it is widely used to identify the mechanisms of environmental teratogens and in therapeutic drug screening. Here, we discuss the value of zebrafish as a model to understand epithelial and NCC induced ectomesenchymal cell activities during early palate morphogenesis and robustness of the zebrafish in modern research on identifying the genetic and environmental etiological factors of CLP. 相似文献
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