全文获取类型
收费全文 | 1048篇 |
免费 | 61篇 |
国内免费 | 5篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 22篇 |
妇产科学 | 6篇 |
基础医学 | 114篇 |
口腔科学 | 27篇 |
临床医学 | 70篇 |
内科学 | 297篇 |
皮肤病学 | 12篇 |
神经病学 | 51篇 |
特种医学 | 48篇 |
外科学 | 222篇 |
综合类 | 10篇 |
预防医学 | 21篇 |
眼科学 | 22篇 |
药学 | 30篇 |
肿瘤学 | 160篇 |
出版年
2023年 | 27篇 |
2022年 | 39篇 |
2021年 | 48篇 |
2020年 | 33篇 |
2019年 | 42篇 |
2018年 | 48篇 |
2017年 | 34篇 |
2016年 | 45篇 |
2015年 | 52篇 |
2014年 | 65篇 |
2013年 | 72篇 |
2012年 | 87篇 |
2011年 | 92篇 |
2010年 | 41篇 |
2009年 | 23篇 |
2008年 | 35篇 |
2007年 | 44篇 |
2006年 | 46篇 |
2005年 | 41篇 |
2004年 | 40篇 |
2003年 | 26篇 |
2002年 | 28篇 |
2001年 | 5篇 |
2000年 | 6篇 |
1999年 | 10篇 |
1998年 | 10篇 |
1997年 | 7篇 |
1996年 | 7篇 |
1995年 | 6篇 |
1994年 | 5篇 |
1993年 | 14篇 |
1992年 | 2篇 |
1991年 | 2篇 |
1990年 | 2篇 |
1989年 | 4篇 |
1988年 | 4篇 |
1987年 | 4篇 |
1986年 | 3篇 |
1985年 | 1篇 |
1982年 | 2篇 |
1981年 | 1篇 |
1980年 | 1篇 |
1979年 | 2篇 |
1978年 | 2篇 |
1977年 | 2篇 |
1976年 | 2篇 |
1973年 | 1篇 |
1969年 | 1篇 |
排序方式: 共有1114条查询结果,搜索用时 15 毫秒
1.
Suguru Yonezawa Yoshifumi Matsushita Hisako Muramatsu Yuko Arita Takao Nakamura Takashi Muramatsu Eiichi Sato 《Pathology international》1987,37(8):1249-1261
Using the surgically extirpated specimens from 9 patients with colorectal carcinoma, fucosyltransferase activities in the carcinoma tissue and the normal mucosa were measured and were compared with the hlstochemical findings of glycoconjugates which were shown by staining with lectins reacting with blood group antigens and related substances. The fucosyltransferase activities of the carcinoma tissue were well correlated with the overall findings of lectin stainings after neuraminidase treatment. The more intense the carcinoma tissue was stained, the higher the fucosyltransferase activity was shown. However, there were marked differences in the fucosyltransferase activities by the portions measured, depending upon the relative amount of carcinoma tissue and Interstitial tissue; in the invasive portion with less carcinoma tissue, the activity was generally low in comparison with that in the surface area where carcinoma tissue was rather abundant. Thus, the morphological and lectin hlstochemical finding are of paramount importance for the eveluation of glycosyltransferase activity in human colorectal carcinoma. 相似文献
2.
3.
4.
5.
6.
Shigematsu R Okura T Nakagaichi M Tanaka K Sakai T Kitazumi S Rantanen T 《The journals of gerontology. Series A, Biological sciences and medical sciences》2008,63(1):76-82
BACKGROUND: Decreased fitness of the lower extremities is a potentially modifiable fall risk factor. This study aimed to compare two exercise programs--square-stepping exercise (SSE), which is a low-cost indoor program, and walking--for improving the fitness of the lower extremities. METHODS: We randomly allocated 68 community-dwelling older adults (age 65-74 years) to either the SSE or walking group (W group). During the 12-week regimen, the SSE group participated in 70-minute exercise sessions conducted twice a week at a local health center, and the W group participated in outdoor supervised walking sessions conducted weekly. The W group was instructed to increase the number of daily steps. Prior to and after the program, we obtained information on 11 physical performance tests for known fall risk factors and 3 self-reported scales. The fall incidence was followed-up for 8 months. RESULTS: At 12 weeks postregimen, significant differences were observed between the two exercise groups with respect to leg power (1 item), balance (2 items), agility (2 items), reaction time (2 items), and a self-reported scale (1 item); the SSE group demonstrated a marked improvement in the above-mentioned items with Group x Time interactions. Significant time effects were observed in the tests involving chair stands, functional reach, and standing up from a lying-down position without Group x Time interactions. During the follow-up period, the fall rates per person-year in the SSE and W groups were 23.4% and 33.3%, respectively (p =.31). CONCLUSION: Although further studies are required, SSE is apparently more effective than walking in reducing fall risk factors, and it appears that it may be recommended as a health promotion exercise in older adults. 相似文献
7.
An 83-year-old woman was transferred to our hospital because of pacing failure and suspected ventricular perforation by a permanent pacing lead. She had undergone permanent pacemaker implantation 5 months previously. Chest radiography showed the pacing lead running out of the cardiac shadow. Computed tomography and echocardiography confirmed the diagnosis of ventricular perforation by the pacing lead. No evidence of cardiac tamponade was found. The lead was surgically removed through a median sternotomy. Intraoperatively, the lead was found perforating the ventricle and the pericardium, and reaching into the left pleural cavity but not injuring the left lung. A pacing lead may potentially injure the heart or the lung. Regular check-up of lead position and pacing status is recommended. 相似文献
8.
Masanori Kitamura Suguru Sasaki Riho Nishikawa Kohei Yamada Munetaka Kunishima 《RSC advances》2018,8(40):22482
In this paper, we discuss the synthesis of imido-substituted chlorotriazines and demonstrate their use in dehydrative condensation reactions. Chemoselective amide-forming reactions of amino alcohols using succinimido-substituted chlorotriazine (2A) proceeded smoothly. Occasionally, nonselectivity was problematic during the synthesis of hydroxy-substituted amides. Moreover, it was noteworthy that this method was applicable to hydroxy-substituted carboxylic acids that could have formed a lactone or an ester during the carboxylic acid activation step. The imido-substituted chlorotriazine (2A) was superior to the amido-substituted chlorotriazine and 2-chloro-4,6-dimethoxy-1,3,5-triazine (CDMT) in terms of reaction rates and yields.In this paper, we discuss the synthesis of imido-substituted chlorotriazines and demonstrate their use in dehydrative condensation reactions. 相似文献
9.
10.
Nobuaki Hoshino Suguru Hasegawa Koya Hida Kenji Kawada Kenichi Sugihara Yoshiharu Sakai 《International journal of colorectal disease》2016,31(7):1307-1313