全文获取类型
收费全文 | 1486篇 |
免费 | 104篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 14篇 |
儿科学 | 138篇 |
妇产科学 | 61篇 |
基础医学 | 205篇 |
口腔科学 | 37篇 |
临床医学 | 130篇 |
内科学 | 250篇 |
皮肤病学 | 22篇 |
神经病学 | 175篇 |
特种医学 | 26篇 |
外科学 | 110篇 |
综合类 | 34篇 |
一般理论 | 4篇 |
预防医学 | 93篇 |
眼科学 | 32篇 |
药学 | 106篇 |
中国医学 | 2篇 |
肿瘤学 | 152篇 |
出版年
2023年 | 23篇 |
2022年 | 33篇 |
2021年 | 55篇 |
2020年 | 42篇 |
2019年 | 47篇 |
2018年 | 66篇 |
2017年 | 39篇 |
2016年 | 49篇 |
2015年 | 54篇 |
2014年 | 86篇 |
2013年 | 95篇 |
2012年 | 142篇 |
2011年 | 116篇 |
2010年 | 69篇 |
2009年 | 54篇 |
2008年 | 77篇 |
2007年 | 79篇 |
2006年 | 68篇 |
2005年 | 65篇 |
2004年 | 52篇 |
2003年 | 46篇 |
2002年 | 70篇 |
2001年 | 16篇 |
2000年 | 13篇 |
1999年 | 5篇 |
1998年 | 15篇 |
1997年 | 10篇 |
1996年 | 11篇 |
1995年 | 6篇 |
1994年 | 3篇 |
1993年 | 3篇 |
1992年 | 6篇 |
1991年 | 4篇 |
1990年 | 5篇 |
1989年 | 4篇 |
1988年 | 5篇 |
1987年 | 3篇 |
1986年 | 3篇 |
1985年 | 3篇 |
1983年 | 3篇 |
1978年 | 3篇 |
1974年 | 3篇 |
1973年 | 6篇 |
1971年 | 3篇 |
1970年 | 3篇 |
1969年 | 3篇 |
1968年 | 5篇 |
1967年 | 4篇 |
1966年 | 3篇 |
1965年 | 2篇 |
排序方式: 共有1591条查询结果,搜索用时 0 毫秒
1.
2.
Psychological sequelae of miscarriage: a controlled study using the general health questionnaire and the hospital anxiety and depression scale. 下载免费PDF全文
This study was carried out to assess whether psychiatric morbidity after a miscarriage is higher than that associated with early pregnancy. A total of 60 consecutive women admitted to a Swansea hospital with a miscarriage were compared with 62 consecutive women who attended an antenatal clinic at the same hospital, using the 28-item general health questionnaire and the hospital anxiety and depression scale. These were completed both at initial contact and six weeks later. Women who had had a miscarriage were found to be significantly more anxious and scored higher on the subscale for severe depression than the pregnant women, both at initial assessment and six weeks later. At the six week assessment more somatic symptoms were also experienced by the group who had had a miscarriage. This study highlights the psychological disturbance associated with miscarriage. The primary health care team and hospital staff need to take this into consideration when organizing follow up for women who have had a miscarriage. 相似文献
3.
L Kent E Green J Holmes A Thapar M Gill Z Hawi M Fitzgerald P Asherson S Curran J Mills A Payton N Craddock 《American journal of medical genetics》2001,105(8):686-689
Attention-deficit hyperactivity disorder (ADHD) is a highly heritable, common psychiatric disorder of childhood that probably involves several genes. There are several lines of evidence suggesting that the nicotinic system may be functionally significant in ADHD. First, nicotine promotes the release of dopamine and has been shown to improve attention in adults with ADHD, smokers, and nonsmokers. Second, ADHD is a significant risk factor for early initiation of cigarette smoking in children and maternal cigarette smoking appears to be a risk factor for ADHD. Finally, animal studies in rats and monkeys also suggest that nicotine may be involved in attentional systems and locomotor activity. The nicotinic system has previously been studied in schizophrenia where the neuronal nicotinic acetylcholine receptor alpha 7 subunit gene (CHRNA7) has been implicated in decreased P50 inhibition and attentional disturbances in patients with schizophrenia and in many of their nonschizophrenic relatives. Three known microsatellite markers (D15S165, D15S1043, and D15S1360) near the nicotinic acetylcholine alpha 7 receptor gene, CHRNA7, were studied in 206 ADHD parent-proband trios of children aged 5-16 with ADHD according to DSM-IV criteria. Children with known major medical or psychiatric conditions or mental retardation (IQ < 70) were excluded from the study. Markers D15S165 and D15S1360 were in linkage disequilibrium. The extended Transmission Disequilibrium Test analyses demonstrated no evidence that variation at the microsatellite markers D15S1360, D15S1043, and D15S165 influences susceptibility to ADHD. However, it remains possible that the CHRNA7 gene and other nicotinic system genes may be involved in conferring susceptibility to ADHD. 相似文献
4.
Donnadieu E Jouvin MH Rana S Moffatt MF Mockford EH Cookson WO Kinet JP 《Immunity》2003,18(5):665-674
Allergic reactions are triggered via crosslinking of the high-affinity receptor for immunoglobulin E, F(c)epsilonRI. In humans, F(c)epsilonRI is expressed as a tetramer (alphabetagamma(2)) and a trimer (alphagamma(2)). The beta subunit is an amplifier of F(c)epsilonRI surface expression and signaling. Here, we show that as a consequence of alternative splicing, the F(c)epsilonRIbeta gene encodes two proteins with opposing and competing functions. One isoform is the full-length classical beta, the other a novel truncated form, beta(T). In contrast to beta, beta(T) prevents F(c)epsilonRI surface expression by inhibiting alpha chain maturation. Moreover, beta(T) competes with beta to control F(c)epsilonRI surface expression in vitro. We propose that the relative abundance of the products of the beta gene may control the level of F(c)epsilonRI surface expression and thereby influence susceptibility to allergic diseases. 相似文献
5.
Zeynep H. Coban‐Akdemir Wu‐Lin Charng Mahshid Azamian Ingrid S. Paine Jaya Punetha Christopher M. Grochowski Tomasz Gambin Santiago O. Valdes Bryan Cannon Gladys Zapata Patricia P. Hernandez Shalini Jhangiani Harsha Doddapaneni Jianhong Hu Fatima Boricha Donna M. Muzny Eric Boerwinkle Yaping Yang Richard A. Gibbs Jennifer E. Posey Xander H. T. Wehrens John W. Belmont Jeffrey J. Kim Christina Y. Miyake James R. Lupski Seema R. Lalani 《American journal of medical genetics. Part A》2020,182(6):1387-1399
6.
7.
8.
9.
Jennifer Yao Nabajit Lahiri Shalini Tripathi Shawn L. Riechers Eugene S. Ilton Sayandev Chatterjee Edgar C. Buck 《RSC advances》2022,12(30):19350
We have developed a specialized microfluidic electrochemical cell that enables in situ investigation of the electrochemical corrosion of microgram quantities of redox active solids. The advantage of downscaling is the reduction of hazards, waste, expense, and greatly expanding data collection for hazardous materials, including radioactive samples. Cyclic voltammetry was used to monitor the oxidation–reduction cycle of minute quantities of micron-size uraninite (UO2) particles, from the formation of hexavalent uranium (U(vi)), U3O7 and reduction to UO2+x. Reaction progress was also studied in situ with scanning electron microscopy. The electrochemical measurements matched those obtained at the bulk-scale and were consistent with ex situ characterization of the run products by X-ray photoelectron spectroscopy, scanning transmission electron microscopy, and atomic force microscopy; thus, demonstrating the utility of the microfluidic approach for studying radioactive materials.Highlight of the multimodal characterization of corrosion behaviour of microgram quantities of UO2, enabled by a novel particle-attached microfluidic electrochemical cell. 相似文献
10.