全文获取类型
收费全文 | 298篇 |
免费 | 18篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 15篇 |
妇产科学 | 4篇 |
基础医学 | 38篇 |
口腔科学 | 68篇 |
临床医学 | 21篇 |
内科学 | 37篇 |
皮肤病学 | 4篇 |
神经病学 | 10篇 |
特种医学 | 9篇 |
外科学 | 49篇 |
综合类 | 5篇 |
预防医学 | 19篇 |
眼科学 | 1篇 |
药学 | 16篇 |
中国医学 | 2篇 |
肿瘤学 | 11篇 |
出版年
2023年 | 4篇 |
2022年 | 9篇 |
2021年 | 15篇 |
2020年 | 5篇 |
2019年 | 9篇 |
2018年 | 7篇 |
2017年 | 7篇 |
2016年 | 4篇 |
2015年 | 12篇 |
2014年 | 13篇 |
2013年 | 16篇 |
2012年 | 16篇 |
2011年 | 19篇 |
2010年 | 12篇 |
2009年 | 8篇 |
2008年 | 9篇 |
2007年 | 12篇 |
2006年 | 20篇 |
2005年 | 22篇 |
2004年 | 15篇 |
2003年 | 7篇 |
2002年 | 9篇 |
2001年 | 9篇 |
2000年 | 10篇 |
1999年 | 8篇 |
1998年 | 7篇 |
1995年 | 1篇 |
1994年 | 1篇 |
1993年 | 2篇 |
1992年 | 9篇 |
1991年 | 3篇 |
1990年 | 8篇 |
1989年 | 1篇 |
1988年 | 1篇 |
1985年 | 2篇 |
1984年 | 1篇 |
1975年 | 1篇 |
1973年 | 1篇 |
1970年 | 1篇 |
排序方式: 共有316条查询结果,搜索用时 187 毫秒
1.
Maria José GaldOn Estrella Durá Yolanda Andreu Maite Ferrando Rafael Poveda José Vicente Bagán 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2006,102(1):40-46
OBJECTIVE: This study analyzes the differences in psychological variables and symptomatology between temporomandibular disorder diagnosis subgroups. STUDY DESIGN: The sample included 114 temporomandibular disorder patients that were evaluated in coping, distress, and temporomandibular characteristics. Diagnostic muscular (n = 58) and articular (n = 56) subgroups were compared in these variables through a MANCOVA. RESULTS: Muscular patients show a higher level of general distress, specifically in the anxiety and somatization subscales and a more active coping style, with a tendency of a minor use of humor and a higher number of parafunctional habits, specifically, biting nails, hangnails, and lips. CONCLUSION: We discuss the differences found in order to design the targets of the psychological intervention of temporomandibular patients. 相似文献
2.
Conversion of myoblasts to physiologically active neuronal phenotype 总被引:13,自引:0,他引:13
Watanabe Y Kameoka S Gopalakrishnan V Aldape KD Pan ZZ Lang FF Majumder S 《Genes & development》2004,18(8):889-900
3.
Analysis of the behavior of eryC mutants of Brucella suis attenuated in macrophages 总被引:1,自引:0,他引:1
下载免费PDF全文
![点击此处可从《Infection and immunity》网站下载免费的PDF全文](/ch/ext_images/free.gif)
The facultatively intracellular pathogen Brucella, characterized by its capacity to replicate in professional and non professional phagocytes, also causes abortion in ruminants. This property has been linked to the presence of erythritol in the placenta, as brucellae preferentially utilize erythritol. The ery operon encodes enzymes involved in erythritol metabolism, and a link with virulence has since been discussed. Allelic exchange mutants in eryC of Brucella suis were erythritol sensitive in vitro with a MIC of 1 to 5 mM of erythritol. Their multiplication in macrophage-like cells was 50- to 90-fold reduced, but complementation of the mutant restored wild-type levels of intracellular multiplication and the capacity to use erythritol as a sole carbon source. In vivo, the eryC mutant colonized the spleens of infected BALB/c mice to a significantly lower extent than the wild type and the complemented strain. Interestingly, eryC mutants that were in addition spontaneously erythritol tolerant nevertheless exhibited wild-type-like intramacrophagic and intramurine replication. We concluded from our results that erythritol was not an essential carbon source for the pathogen in the macrophage host cell but that the inactivation of the eryC gene significantly reduced the intramacrophagic and intramurine fitness of B. suis. 相似文献
4.
Evaluation of DNA probes for specific detection of Vibrio cholerae O139 Bengal. 总被引:2,自引:3,他引:2
下载免费PDF全文
![点击此处可从《Journal of clinical microbiology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
G B Nair P K Bag T Shimada T Ramamurthy T Takeda S Yamamoto H Kurazono Y Takeda 《Journal of clinical microbiology》1995,33(8):2186-2187
Two DNA probes, 2R1 and 2R3, prepared from a region in the chromosome specific for the lipopolysaccharide O side chains of Vibrio cholerae O139 (M.K. Waldor and J.J. Mekalanos, Lancet 343:1366, 1994) were examined for their specificity and sensitivity. Both probes did not hybridize with any strain of V. cholerae belonging to serogroups other than O139 and to any of the other species examined belonging to the family Vibrionaceae. Among the 126 strains of V. cholerae O139 examined, probe 2R1 hybridized with 125 strains while probe 2R3 hybridized with all 126 strains. Both probes were found to be highly specific and sensitive and can be used for the specific identification of V. cholerae O139. 相似文献
5.
6.
Sankar Prasad Bag Prabir Garu Jim-Long Her Bih-Show Lou Tung-Ming Pan 《RSC advances》2018,8(38):21210
In this paper, we developed a high-performance solid-state pH sensor using a Ce0.9Sr0.1(Zr0.53Ti0.47)O4 (CSZT) membrane through a very simple sol–gel spin-coating process. The structural properties of the CSZT membrane are correlated with its sensing characteristics. The CSZT based EIS sensor exhibited a high pH sensitivity of 92.48 mV pH−1, which is beyond the Nernst limit (59.4 mV pH−1), and good reliability in terms of a low hysteresis voltage of 1 mV and a small drift rate of 0.15 mV h−1. This behaviour is attributed to the incorporation of Sr in the CSZT sensing membrane, which promotes change in the Ce oxidation state from Ce4+ to Ce3+.We developed a high-performance solid-state pH sensor using a Ce0.9Sr0.1(Zr0.53Ti0.47)O4 (CSZT) membrane through a very simple sol–gel spin-coating process. 相似文献
7.
8.
José Antonio Becerra Fontal Joan Bagó Granell Josep Garré Olmo Ramón Roig Busquets Francisco Peris Prats Carlos Villanueva Leal 《European spine journal》2013,22(5):1002-1009
Introduction
Despite the high prevalence of musculoskeletal diseases, in Spain there are few data about how these conditions affect the quality of life of individuals. The objective of this study was to assess the quality of life (QOL) of patients candidate for orthopedic surgical treatment using an age–gender adjusted method of QOL scores.Materials and methods
The SF-36 Health Survey was administered to 538 patients candidate for surgery between surgical treatment was classified in four groups (lumbar disease, cervical disease, knee arthroplasty, and hip arthroplasty). Associated morbidities were collected retrospectively for all cases using the Charlson co-morbidity index. Univariate, bivariate, and multivariate statistical analyses were done to compare the four groups to each other, to the general population mean, and to the age and gender-adjusted population mean.Results
234 men and 304 women whose mean age was 58.78 years (19–89) were assessed. Patients candidate for some kind or lumbar surgery had the worst scores in all physical and mental scales as compared to the other disease groups. Patients candidate for knee arthroplasty, had the best quality of life scores in all scales, compared to the other disease groups. Medical conditions had no influence over the summary measures.Conclusion
Presenting the results of SF-36 in standard deviations from the age- and gender-adjusted population mean (T values) leads to a better appreciation of the differences between the various diseases. Patients candidate for surgery of the lumbar spine had a worse QOL, while the QOL in patients candidate for knee arthroplasty was the least affected. 相似文献9.
Bijan Ghassemieh Vivek N. Ahya Maher A. Baz Vincent G. Valentine Selim M. Arcasoy Robert B. Love Harish Seethamraju Charles G. Alex Remzi Bag Nilto C. DeOliveira Wickii T. Vigneswaran Jeff Charbeneau Edward R. Garrity Sangeeta M. Bhorade 《The Journal of heart and lung transplantation》2013,32(7):701-706
10.