全文获取类型
收费全文 | 21828篇 |
免费 | 1182篇 |
国内免费 | 37篇 |
专业分类
耳鼻咽喉 | 551篇 |
儿科学 | 986篇 |
妇产科学 | 856篇 |
基础医学 | 2748篇 |
口腔科学 | 684篇 |
临床医学 | 1536篇 |
内科学 | 4712篇 |
皮肤病学 | 412篇 |
神经病学 | 1738篇 |
特种医学 | 827篇 |
外科学 | 3283篇 |
综合类 | 97篇 |
一般理论 | 4篇 |
预防医学 | 1475篇 |
眼科学 | 640篇 |
药学 | 1667篇 |
中国医学 | 45篇 |
肿瘤学 | 786篇 |
出版年
2023年 | 254篇 |
2022年 | 299篇 |
2021年 | 602篇 |
2020年 | 371篇 |
2019年 | 425篇 |
2018年 | 801篇 |
2017年 | 659篇 |
2016年 | 790篇 |
2015年 | 667篇 |
2014年 | 977篇 |
2013年 | 1263篇 |
2012年 | 1336篇 |
2011年 | 1454篇 |
2010年 | 947篇 |
2009年 | 593篇 |
2008年 | 712篇 |
2007年 | 694篇 |
2006年 | 678篇 |
2005年 | 648篇 |
2004年 | 632篇 |
2003年 | 612篇 |
2002年 | 652篇 |
2001年 | 532篇 |
2000年 | 491篇 |
1999年 | 431篇 |
1998年 | 158篇 |
1997年 | 119篇 |
1992年 | 263篇 |
1991年 | 233篇 |
1990年 | 236篇 |
1989年 | 219篇 |
1988年 | 219篇 |
1987年 | 210篇 |
1986年 | 223篇 |
1985年 | 199篇 |
1984年 | 163篇 |
1983年 | 140篇 |
1979年 | 196篇 |
1978年 | 128篇 |
1976年 | 116篇 |
1975年 | 156篇 |
1974年 | 184篇 |
1973年 | 172篇 |
1972年 | 165篇 |
1971年 | 155篇 |
1970年 | 170篇 |
1969年 | 152篇 |
1968年 | 171篇 |
1967年 | 177篇 |
1966年 | 138篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
Evaluation of Adult versus Pediatric Transesophageal Echocardiography Probe Efficiency for Guiding Septal Puncture during Atrial Fibrillation Ablation
下载免费PDF全文
![点击此处可从《Echocardiography (Mount Kisco, N.Y.)》网站下载免费的PDF全文](/ch/ext_images/free.gif)
3.
Bielik Peter Bonczek Ondřej Krejčí Přemysl Zeman Tomáš Izakovičová-Hollá Lydie Šoukalová Jana Vaněk Jiří Vojtěšek Bořivoj Lochman Jan Balcar Vladimir J. Šerý Omar 《Clinical oral investigations》2022,26(12):7045-7055
Clinical Oral Investigations - The aim of this study was the analysis of WNT10A variants in seven families of probands with various forms of tooth agenesis and self-reported family history of... 相似文献
4.
5.
6.
7.
Irmak Karaca Suzan Güven Yılmaz Melis Palamar Halil Ateş 《Ocular immunology and inflammation》2020,28(6):947-951
ABSTRACT
Purpose
To investigate the effect of 1% tropicamide on anterior chamber aqueous flare (ACAF) measurements acquired with laser flare meter in patients with pseudoexfoliation. 相似文献8.
9.
Stanislas Grassin‐Delyle Michaela Semeraro Frantz Foissac Naim Bouazza Haleema Shakur‐Still Ian Roberts Jean‐Marc Treluyer Saïk Urien 《Fundamental & clinical pharmacology》2019,33(6):670-678
Tranexamic acid (TXA) is an antifibrinolytic drug that reduces surgical blood loss and death due to bleeding after trauma and post‐partum haemorrhage. One key issue for treatment success is early administration. While usually given intravenously, oral and intramuscular use would be useful in specific circumstances. Therefore, an understanding of TXA pharmacokinetics when given via different routes is valuable. The aim of this study was to perform an individual participant data meta‐analysis of pharmacokinetic studies with TXA given to healthy volunteers via different routes. We searched the following databases: PubMed, Web of Science, Wiley Online Library, Elsevier Science Direct and J‐STAGE. Individual subject data were extracted when available, otherwise arithmetic means were used. A population pharmacokinetic model was developed using nonlinear mixed effect modelling. Seven studies were included in the analysis with data from 10 patients for the IV route, six patients for the IM route and 114 patients for the oral route. The pharmacokinetics was ascribed to a two‐compartment model, and the main covariate was allometrically scaled bodyweight. Oral and IM bioavailabilities were 46 and 105%, respectively. For a 70 kg bodyweight, the population estimates were 7.6 L/h for clearance, 17.9 L for the volume of the central compartment, 2.5 L/h for the diffusional clearance and 16.6 L for the peripheral volume of distribution. Larger well‐designed studies are needed to describe the pharmacokinetics of TXA when given IM or as an oral solution before these can be recommended as alternatives to IV. 相似文献
10.
a. lobrano k. blanchard t.l. abell a. minocha w. boone j. wyatt-ashmead † j. fratkin † c. subramony † a. wee jr ‡ g. di nardo § g. barbara § v. stanghellini § & r. de giorgio § 《Neurogastroenterology and motility》2006,18(2):162-167
BACKGROUND AND AIM: Severe dysautonomia may be secondary to viral infections, resulting in impaired autoimmune, cardiovascular, urinary and digestive dysfunction. Herein, we present a case of a 31-year-old white female patient who had severe gastroparesis related to autonomic failure following an episode of acute gastroenteritis. This seems to be the first report providing thorough assessment of the enteric and autonomic nervous system by analysis of full-thickness small intestinal biopsies, cardiovagal testing and autopsy. HOSPITAL COURSE: This patient affected by a severe gastroparesis was treated with antiemetics, prokinetics, analgesics and gastric electrical stimulation to control symptoms. Nutritional support was made using jejunal feeding tube and, in the final stage of disease, with total parenteral nutrition. Autonomic studies revealed minimal heart rate variability and a disordered Valsalva manoeuvre although the enteric nervous system and the smooth muscle layer showed a normal appearance. Hospital courses were complicated by episodes of bacteraemia and fungemia. Serum antiphospholipid antibodies were noted but despite anticoagulation, she developed a pulmonary embolism and shortly thereafter the patient died. Autopsy revealed acute haemorrhagic Candida pneumonia with left main pulmonary artery thrombus. Sympathetic chain analysis revealed decreased myelinated axons with vacuolar degeneration and patchy inflammation consistent with Guillain-Barre syndrome. The evaluation of the enteric nervous system in the stomach and small bowel revealed no evidence of enteric neuropathy or myopathy. CONCLUSION: A Guillain-Barre-like disease with gastroparesis following acute gastroenteritis is supported by physiological and autonomic studies with histological findings. 相似文献