全文获取类型
收费全文 | 258篇 |
免费 | 16篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 5篇 |
妇产科学 | 3篇 |
基础医学 | 30篇 |
口腔科学 | 19篇 |
临床医学 | 31篇 |
内科学 | 23篇 |
神经病学 | 2篇 |
特种医学 | 4篇 |
外科学 | 84篇 |
综合类 | 3篇 |
预防医学 | 6篇 |
眼科学 | 6篇 |
药学 | 28篇 |
中国医学 | 5篇 |
肿瘤学 | 22篇 |
出版年
2023年 | 3篇 |
2022年 | 3篇 |
2021年 | 9篇 |
2020年 | 11篇 |
2019年 | 14篇 |
2018年 | 17篇 |
2017年 | 8篇 |
2016年 | 8篇 |
2015年 | 12篇 |
2014年 | 15篇 |
2013年 | 10篇 |
2012年 | 19篇 |
2011年 | 18篇 |
2010年 | 4篇 |
2009年 | 8篇 |
2008年 | 31篇 |
2007年 | 25篇 |
2006年 | 24篇 |
2005年 | 13篇 |
2004年 | 11篇 |
2003年 | 8篇 |
2002年 | 2篇 |
2000年 | 1篇 |
排序方式: 共有274条查询结果,搜索用时 15 毫秒
1.
2.
3.
Meng-Lay Lin Hetal Patel Judit Remenyi Christopher R.S. Banerji Chun-Fui Lai Manikandan Periyasamy Ylenia Lombardo Claudia Busonero Silvia Ottaviani Alun Passey Philip R. Quinlan Colin A. Purdie Lee B. Jordan Alastair M. Thompson Richard S. Finn Oscar M. Rueda Carlos Caldas Jesus Gil R. Charles Coombes Frances V. Fuller-Pace Andrew E. Teschendorff Laki Buluwela Simak Ali 《Oncotarget》2015,6(25):21685-21703
4.
Ankit Batra Jayachandran Perumal Kalaiyarasi Krishnarathinam Kannan Nikita Mehra Prasanth Ganesan Parathan Karunakaran Manikandan Dhanushkodi Gangothri Selvarajan Arun Kumar Rajan Sivasree Kesana Trivadi Ganesan Tenali G. Sagar Venkatraman Radhakrishnan 《Indian journal of hematology & blood transfusion》2021,37(3):463
There has been a surge in haploidentical hematopoietic stem cell transplantation (HSCT) in India recently. However, there is a paucity of data on haploidentical HSCT from India. The report is an analysis of data of haploidentical HSCT performed at our center. Analysis of patients with acute leukemia or chronic myeloid leukemia who underwent haploidentical HSCT during 2014–2019 was performed. The graft versus host disease (GVHD) prophylaxis was post-transplant Cyclophosphamide with Mycophenolate-mofetil and Cyclosporine. All patients were transfused peripheral blood stem cells from donors. Overall survival (OS) was calculated using the Kaplan–Meier method. Twenty-one patients underwent haploidentical HSCT. Fourteen-patients were males. The median age of patients was 15 years. Fludarabine with total body irradiation was the most common conditioning regimen (n = 15, 71.4%). The median duration for neutrophil and platelet engraftment was 14 days. Cumulative incidence of acute and chronic GVHD was 19%, and 38% respectively. The median follow-up was 26 months and the two-year OS was 38%. Twelve (57%) patients died during the study period, 8 patients (38%) died from transplant-related mortality (TRM), and 4 from disease relapse. Sepsis was the cause of death in six of the eight TRM. Nine out of 21 patients (42.8%) are leukemia-free on follow-up. Haploidentical HSCT is a promising modality of treatment in patients who have no suitable matched donors. Though the TRM remains high, good disease control was achieved in 42.8% of patients. Multi-drug resistant bacterial infection remains a challenge in performing haploidentical HSCT in developing countries. 相似文献
5.
Mehra Nikita Christopher Vasanth Dhanushkodi Manikandan Radhakrishnan Venkatraman Ganesan Trivadi S Ganesharajah Selvaluxmy Sagar Tenali Gnana Ganesan Prasanth 《International journal of clinical pharmacy》2020,42(2):662-666
International Journal of Clinical Pharmacy - Background There is limited data on specific antiemetic protocols for control of chemotherapy-induced nausea/vomiting (CINV) caused by weekly cisplatin... 相似文献
6.
7.
Rajagopalaboopathi Jayasudha Venkatapathy Narendran Palanisamy Manikandan Solai Ramatchandirane Prabagaran 《Journal of clinical microbiology》2014,52(5):1459-1466
Endophthalmitis is a potential vision-threatening complication following surgical procedures (postoperative endophthalmitis [POE]), trauma (posttraumatic endophthalmitis [PTE]), and bacteremic seeding of the eye from a distant infection site (endogenous endophthalmitis [EE]). Several studies have revealed the polybacterial characteristics of endophthalmitis, which make the administration of antibiotics to treat the disease challenging. However, until now, the polybacterial communities of POE, PTE, and EE have not been precisely studied. Hence, the present study was designed to identify the bacterial community of endophthalmitis through 16S rRNA gene libraries. Of the 40 intraocular samples tested, 30 libraries were constructed with bacterial nested-PCR-positive samples. The obtained recombinant clones were screened through amplified rRNA gene restriction analysis (ARDRA) to identify unique clones. The multiple types of ARDRA patterns (P = 0.345) and diverse bacterial sequences (P = 0.277) within the libraries revealed the polybacterial nature of infection in POE, PTE, and EE. Moreover, to the best of our knowledge, this is the first report on polybacterial infection in EE. Gram-positive bacteria, including Bacillus spp. (n = 19), Streptococcus spp. (n = 18), Staphylococcus spp. (n = 6), Exiguobacterium spp. (n = 3), Gemella spp. (n = 2), Enterococcus spp. (n = 2), a Lysinibacillus sp. (n = 1), a Clostridium sp. (n = 1), and a Nocardia sp. (n = 1), and Gram-negative bacteria, including Serratia spp. (n = 18), Pseudomonas spp. (n = 10), Enterobacter spp. (n = 8), Acinetobacter spp. (n = 3), Pantoea spp. (n = 3), a Haemophilus sp. (n = 1), and a Massilia sp. (n = 1), were identified. Interestingly, among them, 10 bacterial species were not previously reported to be associated with endophthalmitis or other ocular infections. Besides, the presence of 4 unidentifiable clones suggests the possibility of novel organisms that might cause eye infections. Therefore, it is recommended that, in addition to the polybacterial nature of POE, PTE, and EE infections, the spectrum of the pathogenic bacterial community identified in this work should be considered while administering antibiotic therapy in suspected endophthalmitis cases. 相似文献
8.
V. Manikandan Ali Mirzaei S. Sikarwar B. C. Yadav S. Vigneselvan A. Vanitha J. Chandrasekaran 《RSC advances》2020,10(23):13611
A sensor displaying a rapid response and high sensitivity was developed by following a simple route. Ionic defects in this sensor were explored using X-ray diffraction analysis. In general, such defects arise from a mismatch of ionic radii, which actually improves the sensing performance. SEM and TEM images of the currently produced particles demonstrated negligible agglomeration, which greatly enhanced the flow of water molecules through the particles. The current sensor showed a rapid response to changes in humidity. Its sensing performance was classified into three different ranges of humidity. Of these humidity ranges, the sensor showed the highest sensitivity (8.84 MΩ per %RH) at low relative humidity (10–20% RH). Furthermore, the sensitivity fall off as the RH was increased from 20 to 99%. The sensor showed a rapid response time of 20 s. Also, the sensor showed 92.98% reproducibility and few effects of aging.A sensor displaying a rapid response and high sensitivity was developed by following a simple route. 相似文献
9.
Cobalt telluride nanostructured materials have demonstrated various applications, particularly in energy generation and storage. A high temperature and reducing atmosphere are required for the preparation of cobalt telluride-based materials, which makes this a difficult and expensive process. The development of a facile route for producing the desirable nanostructure of cobalt telluride remains a great challenge. We demonstrated a simple hydrothermal method for preparing cobalt telluride nanorods (CoTe NRs) and telluride nanorods (Te NRs) for supercapacitor applications. The morphology of CoTe NRs and Te NRs was analyzed using scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The prepared CoTe NR electrode material exhibited a high specific capacity of 170 C g−1 at a current density of 0.5 A g−1 with an exceptional cyclic stability. The asymmetric supercapacitor was assembled using CoTe NRs and orange peel-derived activated carbon (OPAA-700) as a positive and negative electrode, respectively. The fabricated device delivered a high energy density of 40.7 W h kg−1 with a power density of 800 W kg−1 at 1 A g−1 current density. When the current density was increased to 30 A g−1, the fabricated device delivered a high power density of 22.5 kW kg−1 with an energy density of 16.3 W h kg−1. The fabricated asymmetric supercapacitor displayed a good cyclic stability performance for 10 000 cycles at a high current density of 30 A g−1 and retained 85% of its initial capacity for after 10 000 cycles. The prepared materials indicate their applicability for high performance energy storage devices.A one-step hydrothermal derived cobalt telluride nanorods and activated carbon-based hybrid asymmetric supercapacitor delivered a high energy (40.7 W h kg−1) and power density (22.5 kW kg−1) with an electrochemical stability of 85% for 10000 cycles. 相似文献
10.
Rahul Gupta Lalgudi N Dorairajan K Muruganandham Ramanitharan Manikandan Avijit Kumar Santosh Kumar 《JSLS, Journal of the Society of Laparoendoscopic Surgeons》2014,18(3)