全文获取类型
收费全文 | 208篇 |
免费 | 13篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 17篇 |
妇产科学 | 12篇 |
基础医学 | 11篇 |
口腔科学 | 6篇 |
临床医学 | 16篇 |
内科学 | 40篇 |
皮肤病学 | 6篇 |
神经病学 | 3篇 |
外科学 | 26篇 |
综合类 | 18篇 |
预防医学 | 18篇 |
眼科学 | 31篇 |
药学 | 11篇 |
中国医学 | 1篇 |
肿瘤学 | 4篇 |
出版年
2016年 | 3篇 |
2014年 | 2篇 |
2013年 | 6篇 |
2012年 | 1篇 |
2011年 | 2篇 |
2010年 | 10篇 |
2009年 | 10篇 |
2008年 | 2篇 |
2006年 | 2篇 |
2002年 | 3篇 |
2001年 | 1篇 |
2000年 | 2篇 |
1999年 | 5篇 |
1998年 | 9篇 |
1997年 | 4篇 |
1996年 | 11篇 |
1995年 | 7篇 |
1994年 | 7篇 |
1993年 | 4篇 |
1992年 | 1篇 |
1991年 | 5篇 |
1990年 | 3篇 |
1989年 | 5篇 |
1988年 | 1篇 |
1987年 | 5篇 |
1986年 | 2篇 |
1985年 | 3篇 |
1984年 | 5篇 |
1983年 | 7篇 |
1982年 | 4篇 |
1981年 | 1篇 |
1980年 | 3篇 |
1979年 | 3篇 |
1978年 | 3篇 |
1977年 | 3篇 |
1975年 | 1篇 |
1974年 | 3篇 |
1971年 | 1篇 |
1969年 | 1篇 |
1967年 | 1篇 |
1964年 | 2篇 |
1963年 | 3篇 |
1959年 | 4篇 |
1958年 | 10篇 |
1957年 | 11篇 |
1956年 | 10篇 |
1955年 | 12篇 |
1954年 | 11篇 |
1948年 | 4篇 |
1946年 | 1篇 |
排序方式: 共有221条查询结果,搜索用时 15 毫秒
1.
The author is currently working in the office of Health Promotion,Ministry of Health in British Columbia. For the past 17 yearsshe has worked in Health and Welfare Canada as an advocate forcitizen participation in developing health programs and policies. This article is based on her experience as an advocate and bureaucratin translating and mediating health promotion rhetoric intoaction. The Canadian Healthy Communities and Strengthening Communitiesprojects are used as examples in analyzing the opportunitiesand contradictions in building alliances. 相似文献
2.
RITA PEREGO LUIGIA GOZZINI EMANUELE ARLANDINI GIORGIO BOLIS ROBERTO DE CASTIGLIONE 《Chemical biology & drug design》1995,46(5):341-345
Endothelin-1 (ET), the most potent vasoconstrictor yet discovered, is a peptide containirig 21 amino acids with two intrachain disulfide bridges. With the aim of obtaining two-chain derivatives, Et was submitted to chemical and enzymatic treatments. Reaction of ET with CNBr in 70% HCOOH gave, in addition to the expected [Hse7 lactone]-7,8-seco-ET and unreacted material, a by-product whose molecular weight was 25 m.u. greater than that of ET. When the reaction mixture, after lyophilisation, was immediately quenched with NH3-saturated dry MeOH, two products could be recovered in a 5:1 ratio, both obtained by nucleophilic attack of the homoserine lactone: the expected [Hse7-NH2]-7,8-seco-ET and [Hse7]ET, resulting from competitive intramolecular reaction of the deprotonated α-amino group of the Asp8 residue. The Lys9-Glu10 bond turned out to be very resistant to enzymatic attack both by Lys-C-endopeptidase and trypsin. The 9,10-seco-ET derivative could be obtained by treatment with Lys-C-endopeptidase only by using a high enzyme/ET ratio and after a prolonged incubation time. Cleavage of the Lys9-Glu10 bond could not be achieved by treatment with trypsin, even with a high enzyme/substrate ratio. The main product was 13, 14-seco-ET, deriving from the action of chymotripsin (present as an impurity in the trypsin preparation) on Tyr13. The structure of these peptides was confirmed by amino-acid sequence analysis and fast atom bombardment mass spectrometry (FAB-MS). Nicking of the ET structure at different positions had different impact on the biological properties of the resulting derivatives. © Munksgaard 1995. 相似文献
3.
4.
Role of epidural medication through caudal route was studied in 109 patients having lumbago with or without sciatica to highlight the value of this mode of treatment which relieved symptoms in more than 70% of cases without hospitalisation and without being off work for long periods as in usual methods of conservative treatment.KEY WORDS: Epidural medication, Backache, Lumbago, Sciatica 相似文献
5.
6.
CRISTIANE MARIA DA COSTA‐SILVA FABIANO JEREMIAS JULIANA FELTRIN
De SOUZA RITA
De CÁSSIA LOIOLA CORDEIRO LOURDES SANTOS‐PINTO ANGELA CRISTINA CILENSE ZUANON 《International journal of paediatric dentistry / the British Paedodontic Society [and] the International Association of Dentistry for Children》2010,20(6):426-434
International Journal of Paediatric Dentistry 2010; 20: 426–434 Background. The prevalence of molar incisor hypomineralization (MIH) varies considerably around the world; however, few studies have examined MIH in South American countries. Objective. To evaluate the prevalence, severity, and clinical consequences of MIH in Brazilian children residing in rural and urban areas of the municipality of Botelhos, Minas Gerais, Brazil. Methods. Children aged 6 to 12 years (n = 918) with all four‐first permanent molars erupted had these teeth evaluated according to the European Academy of Paediatric Dentistry (EAPD) criteria. The examinations were conducted by two previously trained examiners, and the dental impact caused by MIH was evaluated with the Decayed, Missing and Filled Teeth (DMFT) index (WHO). Results. Molar incisor hypomineralization was present in 19.8% of the 918 children, with a higher prevalence in rural areas. The majority of the defects presented were demarcated opacities without post‐eruptive structural loss, which has been considered as mild defects. Children with MIH had higher DMFT values. Conclusion. Despite the high prevalence of MIH, the severity of the defects was mild. The results indicate a positive association between MIH and the presence of dental caries. 相似文献
7.
D. K. AGARWAL S. K. UPADHYAY K. N. AGARWAL 《Acta paediatrica (Oslo, Norway : 1992)》1989,78(1):115-122
ABSTRACT. Cognitive development of 1336 children (6–8 yr) was studied in relation to their nutritional status. Seven Piagetian tasks covering the mental process of a concrete operational period were given to each child to assess the cognitive development. Weschler intelligence scale for Indian Children was used to assess the IQ of each child. The percentage of malnourished children in stage I of development (preoperational) was significantly higher as that of wellnourished children. A higher percentage of children in the latter group was in stage III of development (concrete operation). In boys performance on all the tasks was influenced by undernutrition except for class inclusion. In girls this was true only for conservation of liquid, substance and ordinal relation. "he results of the regression analysis showed that nutrition was the only thctor weakly assdated with the poor performance of the children En various tasks. Further, the effect of nutrition was more pronounced in conservation tasks indicating poor verbal reasoning aud comprehension in malnourished children. Information was also collected regarding the parental education and occupation, socio-economic status, caste, economic sufficiency, psychosocial stimulation and home environment. However, these environmental factors did not inflnence the development of rnl children. This might be due to the fact that the population in the present study did not vary much with regard to these variables. 相似文献
8.
9.
Many anaesthetics effect the latency and amplitude of somatosensory evoked potentials (SSEP). We present a patient who underwent two anterior/posterior spine fusions (A/PSF) at age 11 and 12 years old after resection of a spinal astrocytoma. She did have residual neurologic deficits of her lower extremities. SSEPs were unobtainable during the first surgery using an opioid-based anaesthetic. A ketamine-based anaesthetic was used for the second surgery and SSEPs were easily monitored. No other factors seem to have changed between the two surgeries. The anaesthetic management during each procedure is reviewed and the contributions of other factors to SSEP monitoring discussed. 相似文献