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排序方式: 共有162条查询结果,搜索用时 15 毫秒
1.
Stepanova E. S. Makarenkova L. M. Chistyakov V. V. Rybakov Yu. L. Gukasov V. M. Fedotcheva T. A. Parshin V. A. Votyakov V. A. Shimanovskii N. L. 《Pharmaceutical Chemistry Journal》2019,52(12):1016-1020
Pharmaceutical Chemistry Journal - An HPLC-MS method for simultaneous quantitative determination of a novel gestagenic pharmaceutical and two of its metabolites in rat and rabbit blood sera was... 相似文献
2.
M. D. Mashkovskii V. A. Parshin R. B. Parimbetova 《Bulletin of experimental biology and medicine》1997,123(3):257-259
It is found that the cholinomimetic aceclidine stimulates learning and memory processes and exerts antiamnestic effect in
rats with conditioned avoidance reaction. The effect of aceclidine is not inferior to that of amiridin and surpasses that
of physostigmine.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 123, No. 3, pp. 296–298, March, 1997 相似文献
3.
T. V. Golovko N. I. Mikerova L. M. Alekseeva G. A. Bogdanova V. A. Parshin V. V. Asnina R. B. Parimbetova V. G. Granik 《Pharmaceutical Chemistry Journal》1994,28(4):236-242
Translated from Khimiko-farmatsevticheskii Zhurnal, Vol. 28, No. 4, pp. 22–26, April, 1994. 相似文献
4.
The synthesis and localization of alternatively spliced fibronectin EIIIB in resting and thrombin-treated megakaryocytes 总被引:1,自引:1,他引:0
There are several species of alternatively spliced fibronectin (FN). One of these, FN EIIIB, is primarily present in embryonic and in proliferating and migrating cells and is believed to be important for cell maturation. We have studied the synthesis, localization, and secretion of this FN isoform in isolated guinea pig megakaryocytes, nonmegakaryocytic bone marrow cells, and platelets. There was 7.5 times more general FN in megakaryocytes than in nonmegakaryocytic cells based on the analysis of equivalent amounts of protein. FN EIIIB was detected by Western blotting in megakaryocytes but not in nonmegakaryocytic cells present in bone marrow. Neither megakaryocytes nor platelets secreted FN EIIIB, while megakaryocytes secreted 25.3% +/- 4.6% general FN and platelets secreted about 61% general FN in response to thrombin. Analysis of immunostained cells by confocal microscopy revealed that FN EIIIB had been redistributed to the surface of megakaryocytes in response to thrombin. Synthesis was studied by metabolic labeling, and megakaryocytes were shown to synthesize FN and FN EIIIB. Thus, megakaryocytes and platelets are among a small number of adult cells and tissues that synthesize and contain FN EIIIB. The expression of FN EIIIB on the megakaryocyte surface may influence migration and maturation. 相似文献
5.
6.
I. P. Isakovich V. A. Azimov S. Yu. Ryabova L. M. Alekseeva V. P. Parshin R. D. Syubaev R. B. Parimbetova V. V. Asnina I. S. Salimova V. G. Granik 《Pharmaceutical Chemistry Journal》1995,29(2):100-105
Derivatives of 3-aminomethylene-1-(2,6-dichloro)phenyloxindole and 2-aminomethyleneindoxyl were synthesized. The1H and13C NMR spectra and pharmacology of the compounds were studied. 相似文献
7.
Avrunin AS Kornilov NV Sukhanov AV Parshin VA 《Morfologii?a (Saint Petersburg, Russia)》1999,116(6):48-54
Chronobiological characteristics of temporal [correction of temper]-dimensional organization of compact bone remodelling in right tibia after the femoral diaphysis osteotomy on the same side were studied using roentgenometry and roentgenodensitometry. These characteristics were studied in experiments on 179 outbred male albino rats. Circaseptan periodicity of osseous tissue reorganization was established. 相似文献
8.
F. H. BOSCH J. M. WERRE B. ROERDINKHOLDER-STOELWINDER T. H. HULS S. G. L. VD. VEGT F. L. A. WILLEKENS M. BINS M. R. HALIE 《International journal of laboratory hematology》1993,15(4):265-274
Summary A recently described separation technique consisting of a combination of counterflow centrifugation and subsequent density (Percoll) scparation was tested for its ability to enrich red cell populations with young cells in comparison to either separation technique alone. The relative age of every fraction was determined by HbAlc measurements, resulting in the lowest HbAlc for the combination method. Conventional reticulocyte counting and floweytometric counting with thiazole orange indicated that in the youngest fractions the combination method showed the highest reticulocyte counts. There was a good correlation between manual and flowcytometric counting results. Radio-iron studies showed a two-fold enrichment with young cells in the fraction with the lowest HbAIc acquired by the combination technique in comparison to the other two methods. Cytometric measurements showed that the fractions with the lowest HbAlc were the ones with the highest MCV and MCH and the lowest MCHC. Besides loss of their RNA-material, young cells already seem to loose water and haemoglobin like older cells, resulting in a decrease of MCV and MCH and in increase in MCHC. It is concluded that combining counterflow centrifugation with subsequent density fractionation results in superior enrichment with young cells in comparison to the results of each method alone. 相似文献
9.
10.
Akopdzhanov A. G. Shimanovskii N. L. Borisova A. I. Parshin V. A. Frolov G. A. 《Pharmaceutical Chemistry Journal》2020,53(12):1164-1167
Pharmaceutical Chemistry Journal - Ultra-small ferrite nanoparticles containing bivalent metal atoms (Fe, Mn, Mg, and Co) were synthesized as platforms for magnetic-resonance contrast agents... 相似文献