排序方式： 共有7条查询结果，搜索用时 15 毫秒
1
1.
Rosalind P. Candelaria Palita Hansakul Alastair M. Thompson Huong Le-Petross Vicente Valero Roland Bassett Monica L. Huang Lumarie Santiago Beatriz E. Adrada 《American journal of surgery》2018,215(4):693-698
Background
To determine the cancer yield of stereotactic biopsy of suspicious calcifications identified within 24 months after breast conservation therapy (BCT).Methods
Retrospective review of stereotactic biopsies performed during 2009–2013 for suspicious calcifications in the ipsilateral breast of patients who completed BCT.Results
94/2773 (3.4%) had stereotactic biopsies for suspicious calcifications in the ipsilateral breast; 7/94 (7.4%) had DCIS (6) or invasive (1) cancer; 5/7 occurred in the same breast quadrant as the primary. All 7 originally had negative surgical margins (≥2 mm); 6 received whole breast irradiation, and 2 received adjuvant chemotherapy + endocrine therapy. Median time to detection was 11 months (range, 6–20 months). There was a strong association between calcification morphology (particularly pleomorphic) and likelihood of malignancy (p = 0.008).Conclusions
Stereotactic biopsy of calcifications identified within 24 months post-BCT has a 7% cancer yield. Tissue biopsy should be performed rather than imaging followup alone when breast calcifications have suspicious morphology. 相似文献2.
Debata Subrat Palita Sharat Kumar 《Proceedings of the National Academy of Sciences, India. Section B.》2020,90(2):353-363
Proceedings of the National Academy of Sciences, India Section B: Biological Sciences - Species richness, diversity and abundance of bat fauna in Similipal Biosphere Reserve were studied during... 相似文献
3.
4.
Purohit Swetashree Khamari Barsha Priyadarshini Palita Sharat Kumar 《Proceedings of the National Academy of Sciences, India. Section B.》2021,91(2):423-429
Proceedings of the National Academy of Sciences, India Section B: Biological Sciences - Green Munia (Amandava formosa) is an endemic Indian species threatened by pet trading and reduction in the... 相似文献
5.
Suthida Suwanvecho Harit Suwanrusme Tanawat Jirakulaporn Surasit Issarachai Nimit Taechakraichana Palita Lungchukiet Wimolrat Decha Wisanu Boonpakdee Nittaya Thanakarn Pattanawadee Wongrattananon Anita M Preininger Metasebya Solomon Suwei Wang Rezzan Hekmat Irene Dankwa-Mullan Edward Shortliffe Vimla L Patel Yull Arriaga Gretchen Purcell Jackson Narongsak Kiatikajornthada 《J Am Med Inform Assoc》2021,28(4):832
6.
C. Ngamkitidechakul K. Jaijoy P. Hansakul N. Soonthornchareonnon S. Sireeratawong 《Phytotherapy research : PTR》2010,24(9):1405-1413
Phyllanthus emblica Linn. (PE) is a medicinal fruit used in many Asian traditional medicine systems for the treatment of various diseases including cancer. The present study tested the potential anticancer effects of aqueous extract of PE in four ways: (1) against cancer cell lines, (2) in vitro apoptosis, (3) mouse skin tumourigenesis and (4) in vitro invasiveness. The PE extract at 50–100 µg/mL significantly inhibited cell growth of six human cancer cell lines, A549 (lung), HepG2 (liver), HeLa (cervical), MDA‐MB‐231 (breast), SK‐OV3 (ovarian) and SW620 (colorectal). However, the extract was not toxic against MRC5 (normal lung fibroblast). Apoptosis in HeLa cells was also observed as PE extract caused DNA fragmentation and increased activity of caspase‐3/7 and caspase‐8, but not caspase‐9, and up‐regulation of the Fas protein indicating a death receptor‐mediated mechanism of apoptosis. Treatment of PE extract on mouse skin resulted in over 50% reduction of tumour numbers and volumes in animals treated with DMBA/TPA. Lastly, 25 and 50 µg/mL of PE extract inhibited invasiveness of MDA‐MB‐231 cells in the in vitro Matrigel invasion assay. These results suggest P. emblica exhibits anticancer activity against selected cancer cells, and warrants further study as a possible chemopreventive and antiinvasive agent. Copyright © 2010 John Wiley & Sons, Ltd. 相似文献
7.
Background
Super-refractory status epilepticus (SRSE) is a seizure that continues >24?h after anesthesia, or recurs on the reduction of anesthesia. SRSE is extremely difficult-to-control and associated with poor outcome. To date, optimal therapy and outcome data in children is limited.Objective
To assess etiology, treatment options and outcome in pediatric SRSE patients.Method
We reviewed medical records of children <15?years old with SRSE during 2007–2017 at King Chulalongkorn Memorial Hospital. Demographic data, etiology, treatment, complications and discharge outcome were recorded.Results
Seventeen patients, aged 1?month–13?years were included. The leading etiology was immune-mediated encephalitis (29.4%) and epilepsy (29.4%). The most common anesthetic agents were midazolam (94.1%) and propofol (52.9%) with the average maximal dose of 1.3 and 6.9?mg/kg/h respectively. Other treatments included immunological therapy (76.5%), ketogenic diet (76.5%), pyridoxine/pyridoxal-5-phosphate (70.5%). The most common complications were hypotension (61.5%), drug hypersensitivity (32.5%). Median length of anesthetic and intensive care were 9 and 23?days. The mortality rate was 17.6%, and 2 of 3 febrile infection-related epilepsy syndrome cases died. At discharge, all survivors were seizure free.Conclusion
The majority of pediatric SRSE does not have epilepsy and the etiology is various. Treatment should expand from antiepileptic drugs to other modalities targeting different possible mechanisms such as immunomodulation or specific metabolic treatment. Multiple anesthetic drugs could be tolerated with close monitoring. Ketogenic diet, via enteral or parenteral route, could be considered early if requiring multiple anesthetic drugs. Initial outcome in children is relatively better than in adults. 相似文献
1