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1.
Long-term results after 'floppy' Nissen/Rossetti fundoplication for gastroesophageal reflux disease.
Eighty-two patients (median age, 51 years; range, 27-87 years) with refractory gastroesophageal reflux disease (GERD) underwent floppy Nissen/Rossetti fundoplication during the period 1980 to 1990. The median postoperative hospital stay was 5 days (3-16). Median follow-up was 72 months and included endoscopy and a clinical and a questionnaire assessment. Subjective symptoms of reflux were abolished in 98%, and 96% of the patients were satisfied with the results. Endoscopy showed healing of the esophagitis in 98%. There had been no disruption of the fundoplication. Twenty patients complained of gaseous distention and increased flatulence; only two of them had severe problems. Three patients were unable to belch. In conclusion, the floppy fundoplication has been an effective operation with no deaths, a low incidence of morbidity and adverse side effects, and without a tendency for late failure. 相似文献
2.
Linda R White Lars Jacob Stovner Maurice B Vincent Ole Petter Løbben Yara D Fragoso Kristian S Bjerve Ottar Sjaastad 《Cephalalgia : an international journal of headache》1992,12(2):107-110
Our group has previously reported significant changes in the incorporation of precursors into glycerophospholipids, particularly phosphatidylserine, in polymorphonuclear cells obtained from the peripheral blood of cluster headache patients, when compared with controls. The potential of these results led to further work using both the previous methodology and a modified isolation technique to obtain polymorphonuclear cells in as pure a state as possible. Neither the new results obtained using the original technique, nor the results with high purity polymorphonuclear cells from controls and cluster headache patients, confirm the marked changes in precursor uptake into glycerophospholipids originally reported. 相似文献
3.
A total of 316 patients were included in a play-the-winner (PTW) designed study comparing the safety of enoxaprain started preoperatively versus postoperatively as prophylaxis against venous thromboembolism for digestive surgery. In a PTW-designed study the treatment of any next patient depends on the outcome of the previous patient. If successful, the next patient receives the same treatment, if not, the comparative regimen is given. Excessive bleeding according to specified criteria, severe adverse reactions, clinically detected deep venous thrombosis (DVT), or pulmonary embolism (PE) were criteria for classification as “loser.” The PTW design allocates most patients to the superior treatment. The main variable in PTW studies is the number of consecutive patients receiving the same treatment. In this study 163 patients were allocated to postoperatively started and 153 to preoperatively started prophylaxis with enoxaparin. The frequency of “winners” was found to be 82.8% and 78.4% in the post- and preoperatively treated groups, respectively. No significant differences were found between the groups with regard to frequency of “winners” or the number of consecutive patients before change of treatment. The percentile of survival distribution did not detect superiority of any group. Prophylaxis against postoperative venous thromboembolism for digestive surgery using enoxaparin can safely be started preoperatively. 相似文献
4.
Aasdahl Lene Vasseljen Ottar Gismervik Sigmund Østgård Johnsen Roar Fimland Marius Steiro 《Journal of occupational rehabilitation》2021,31(4):721-728
Journal of Occupational Rehabilitation - Purpose There is a lack of results on long-term effects of return to work interventions. We previously reported that an inpatient multimodal occupational... 相似文献
5.
Adrian Montesano Stephen Madigan Kevser Çakmak Ottar Ness Stein Roger Brønseth 《Journal of clinical psychology》2023,79(6):1521-1536
This article outlines a new supervision practice of narrative therapy-informed reflecting team-based relational interviewing for a high-conflict stuck case of a separated middle-aged couple. The article demonstrates the supervision method consisting in five parts. First, the supervisor interviews the couples' relationship while the team watches from behind the one-way mirror. Second, the team responds to the interview while the couple and the supervisor witness their conversation. The couple is then invited to respond back to the team. Furthermore, there is a meta-conversation about the supervision in collaboration with the couple. The intervention ends with therapeutic letter writing to the relationship. The couple showed a meaningful shift in their positioning towards a more relational awareness and found valuable ways for continuing their therapy. The theoretical elements of the approach underpinning practice to tackle high conflict are considered through the illustration of the case. 相似文献
6.
Piotr Kruszewski Maria Luisa Fasano AIf O. Brubakk Jie Ming Shen Trond Sand Ottar Sjaastad 《Headache》1991,31(6):399-405
The recently described "Sunct" syndrome is a rare picture of unilateral, shortlasting headache attacks accompanied by autonomic phenomena (conjunctival injection, tearing, etc.) on the symptomatic side. Heart rate and blood pressure were monitored in two elderly "Sunct" patients during and outside headache attacks. An ultrasound Doppler servo method was used for the non-invasive, continuous, beat-to-beat determination of instantaneous arterial blood pressure. In a third patient, systolic and diastolic blood pressure, both outside and during pain paroxysms, were assessed using the standard Korotkoff method. Heart rate was found to be significantly decreased during pain paroxysms. Systolic blood pressure was observed to be significantly increased during attacks, when compared with the inter-attack period, while a less consistent pattern was observed for diastolic blood pressure. Some of the changes in the cardiovascular system seemed to start prior to pain onset. Therefore, it seems unlikely that these changes were caused by pain activation of the sympathetic nervous system or the oculocardiac reflex. 相似文献
7.
8.
Ottar Dybing Hans Georg Holzhausen 《Naunyn-Schmiedeberg's archives of pharmacology》1939,194(2-5):248-259
Zusammenfassung Sämtliche bekannten Eiweißfraktionen des Herz- und des Skeletmuskels vermögen Digitalisglykoside in erheblicher Menge zu binden. Die Bindungsgröße der Skeletmuskeleiweißkörper ist etwa gleich groß. Das Myogen des Herzmuskels bindet fast doppelt soviel Glykosid wie die Eiweißfraktionen des Skeletmuskels und etwa viermal soviel wie das Globulin X und das Myosin des Herzmuskels. Die Bindung an die Herzmuskeleiweißkörper zeigt eine größere Reversibilität als die an die des Skeletmuskels. 相似文献
9.
Ottar Sjaastad 《Scandinavian journal of gastroenterology》2013,48(3):173-187
Faeces from patients with dystrophia myotonica and controls were incubated aerobically for 20-24 hours with L-histidine, L-carnosine, histamine diphosphate, N-acetylhistamine, and N-acetyl-L-histidine.Whereas inherent histamine-like activity is stable in faeces from patients with dystrophia myotonica, histamine added to faeces with inherent histamine-like activity is degraded, although to a lesser degree than histamine added to patient faeces with low inherent histamine-like activity or to control faeces.N-acetylhistamine is degraded in both control and patient faeces and a bioactive substance appears that seems to be identical with free histamine. N-acetyl-L-histidine also seems to be catabolized to free histamine in patient faeces.In patient faeces with high inherent histamine-like activity, L-histidine is converted to histamine to a greater proportion than to urocanic acid and dihydrourocanic acid. The latter metabolites are prominent in control faeces, whereas only minute amounts of histamine are formed. On prolonged incubation, however, ample amounts of histamine are formed, and then the stability of Chistamine added to control faeces seems to increase. L-carnosine is also converted to a biologically active substance.In dystrophia myotonica increased formation seems to be the main cause of the high inherent faecal histamine-like activity. 相似文献