全文获取类型
收费全文 | 534篇 |
免费 | 84篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 9篇 |
儿科学 | 22篇 |
妇产科学 | 4篇 |
基础医学 | 70篇 |
口腔科学 | 19篇 |
临床医学 | 45篇 |
内科学 | 116篇 |
皮肤病学 | 10篇 |
神经病学 | 39篇 |
特种医学 | 66篇 |
外科学 | 89篇 |
综合类 | 7篇 |
预防医学 | 28篇 |
眼科学 | 8篇 |
药学 | 21篇 |
中国医学 | 1篇 |
肿瘤学 | 66篇 |
出版年
2023年 | 14篇 |
2021年 | 14篇 |
2020年 | 7篇 |
2019年 | 5篇 |
2018年 | 12篇 |
2017年 | 13篇 |
2016年 | 17篇 |
2015年 | 16篇 |
2014年 | 17篇 |
2013年 | 32篇 |
2012年 | 20篇 |
2011年 | 20篇 |
2010年 | 19篇 |
2009年 | 25篇 |
2008年 | 18篇 |
2007年 | 25篇 |
2006年 | 14篇 |
2005年 | 19篇 |
2004年 | 14篇 |
2003年 | 20篇 |
2002年 | 7篇 |
2001年 | 20篇 |
2000年 | 12篇 |
1999年 | 11篇 |
1998年 | 21篇 |
1997年 | 13篇 |
1996年 | 16篇 |
1995年 | 8篇 |
1994年 | 11篇 |
1993年 | 7篇 |
1992年 | 5篇 |
1990年 | 10篇 |
1989年 | 12篇 |
1988年 | 12篇 |
1987年 | 5篇 |
1986年 | 8篇 |
1985年 | 10篇 |
1984年 | 7篇 |
1983年 | 7篇 |
1982年 | 8篇 |
1980年 | 5篇 |
1979年 | 8篇 |
1978年 | 5篇 |
1977年 | 4篇 |
1976年 | 7篇 |
1974年 | 6篇 |
1971年 | 3篇 |
1970年 | 5篇 |
1968年 | 7篇 |
1967年 | 3篇 |
排序方式: 共有620条查询结果,搜索用时 31 毫秒
1.
2.
3.
In vitro and in vivo precipitation of iodinated contrast agents when ioxaglate and papaverine are given together has been reported. To verify these reports and to investigate other medications not previously tested, the authors analyzed mixtures of contrast agents and medications in vitro with a light spectrophotometer and observed them for visible precipitates for up to 120 minutes. Previously reported incompatibilities between ionic or low-osmolality contrast media and medications were verified, and several new incompatibilities were discovered. No incompatibilities were found when the drugs tested were mixed with the new nonionic contrast media. 相似文献
4.
Sequential contrast-enhanced MR imaging of the penis 总被引:1,自引:0,他引:1
5.
Chlamydial etiology of acute lower respiratory tract infections in children in the Sudan 总被引:2,自引:0,他引:2
B Herrmann MAM Salih BE Yousif O Abdelwahab P-A Mårdh 《Acta paediatrica (Oslo, Norway : 1992)》1994,83(2):169-172
The role of Chlamydia pneumoniae in 110 Sudanese children with signs of acute lower respiratory tract infections (ALRI) was investigated. Four (3.6%) had evidence of C. pneumoniae infection, of whom 3 were culture-positive, while 1 had an antibody response suggesting a recent infection. IgG antibodies at a titer of ≥1:32 to C. pneumoniae, Chlamydia psittaci and Chlamydia trachomatis were detected in 27 (24.5%), 27 (24.5%) and 7 (6.4%) of the 110 ALRI cases, respectively. C. pneumoniae, C. trachomatis or C. psittaci were not detected in nasopharyngeal secretions from any of 110 patients when fluorescence-labeled specific monoclonal antibodies were used. In a seroepidemiological survey, 318 healthy Sudanese persons aged between 1 month and 67 years were studied for C. pneumoniae antibodies. 相似文献
6.
P. VON DEN DRIESCH C. STEFFAN A. ZÖBE O.P. HORNSTEIN 《Clinical and experimental dermatology》1994,19(3):274-277
We report the case of a 39-year-old female patient suffering from Sweet's syndrome after an upper respiratory tract infection. Cyclosporin A at a dose of 10 mg/kg per day was given as initial treatment. Skin lesions and general malaise resolved within 9 days. The cyclosporin dose was decreased within 21 days, without recurrence of the eruption. Cyclosporin is a potent inhibitor of T lymphocytes, but affects granulocyte and monocyte functions as well. Success of treatment in our case shows that cyclosporin represents an alternative to steroid treatment in patients with Sweet's syndrome. 相似文献
7.
Polymorphism analysis of four canine MHC class I genes 总被引:1,自引:0,他引:1
Abstract: We have studied the variability of four structurally complete dog leukocyte antigen (DLA) class I genes, termed DLA-12, -88, -79 and -64, in a population of mixed breed, unrelated dogs. The human HLA and canine DLA loci share a high degree of similarity in terms of gene structure. This analysis focused on the first three exons of each of four complete canine genes. Exons two and three are the major source of polymorphism in the corresponding human genes. In this analysis, DLA-88 was found to be significantly more polymorphic than the other three genes, with 44 distinct alleles observed among 63 mixed breed, unrelated dogs. The remaining genes had between one and four alleles when examined in 25 dogs. This work was carried out as part of an effort to develop an MHC typing system for the dog, which is critical to the further development of preclinical studies of hematopoietic stem cell and solid organ transplantation in the canine model. 相似文献
8.
Dynamic particle image velocimetry (PIV) was applied to the study of the flow field associated with prosthetic heart valves.
The results were compared with those of laser Doppler anemometry (LDA). Anatomically and antianatomically oriented Jyros (JR)
and St. Jude Medical (SJM) valves were compared in the mitral position to study the effects of valve design on the downstream
flow field. The experimental program used a dynamic PIV system utilizing high-speed, high-resolution video to map the true
time-resolved velocity field inside the simulated ventricle. This system was complemented by a study using the more traditional
LDA system for comparison. Based on the experimental data, the following general conclusions can be made. High-resolution
dynamic PIV can capture true chronological changes in the velocity and turbulence fields. It also produces very detailed velocity
and turbulence information comparable to the LDA results. In the vertical measuring plane that passes both the center of the
aortic and mitral valves (A-A section), the two valves (the SJM and the JR) show distinct circulatory flow patterns when the
valve is installed in the antianatomical orientation. Small differences in valve design can generate noticeable differences,
particularly during the accelerating flow phase. The SJM valve maintains a relatively high velocity through the central orifice;
the curved leaflets of the JR valve generate higher velocities with a divergent flow during the accelerating and peak flow
phases. In the velocity field directly below the mitral valve and normal to the previous measuring plane (B-B section), where
characteristic differences in valve design will be visible, symmetrical twin circulations were observed because of the divergent
nature of the flow generated by the two inclined half-disks installed in the antianatomical orientation. The SJM valve, with
a central downward flow near the valve, is contrasted with the JR valve, which has a peripheral downward circulation with
higher, turbulent stresses. 相似文献
9.
10.
Robin K. Avery Jennifer D. Motter Kyle R. Jackson Robert A. Montgomery Allan B. Massie Edward S. Kraus Kieren A. Marr Bonnie E. Lonze Nada Alachkar Mary J. Holechek Darin Ostrander Niraj Desai Madeleine M. Waldram Shmuel Shoham Seema Mehta Steinke Aruna Subramanian Janet M. Hiller Julie Langlee Sheila Young Dorry L. Segev Jacqueline M. Garonzik Wang 《American journal of transplantation》2021,21(4):1564-1575
Desensitization has enabled incompatible living donor kidney transplantation (ILDKT) across HLA/ABO barriers, but added immunomodulation might put patients at increased risk of infections. We studied 475 recipients from our center from 2010 to 2015, categorized by desensitization intensity: none/compatible (n = 260), low (0-4 plasmaphereses, n = 47), moderate (5-9, n = 74), and high (≥10, n = 94). The 1-year cumulative incidence of infection was 50.1%, 49.8%, 66.0%, and 73.5% for recipients who received none, low, moderate, and high-intensity desensitization (P < .001). The most common infections were UTI (33.5% of ILDKT vs. 21.5% compatible), opportunistic (21.9% vs. 10.8%), and bloodstream (19.1% vs. 5.4%) (P < .001). In weighted models, a trend toward increased risk was seen in low (wIRR = 0.771.402.56,P = .3) and moderately (wIRR = 0.881.352.06,P = .2) desensitized recipients, with a statistically significant 2.22-fold (wIRR = 1.332.223.72,P = .002) increased risk in highly desensitized recipients. Recipients with ≥4 infections were at higher risk of prolonged hospitalization (wIRR = 2.623.574.88, P < .001) and death-censored graft loss (wHR = 1.154.0113.95,P = .03). Post–KT infections are more common in desensitized ILDKT recipients. A subset of highly desensitized patients is at ultra-high risk for infections. Strategies should be designed to protect patients from the morbidity of recurrent infections, and to extend the survival benefit of ILDKT across the spectrum of recipients. 相似文献