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排序方式: 共有1177条查询结果,搜索用时 15 毫秒
1.
U N Jindal 《The international journal of tuberculosis and lung disease》2006,10(9):1045-1050
SETTING: A private infertility care and in vitro fertilisation (IVF) centre in Northern India. OBJECTIVES: To describe the prevalence, clinical spectrum, management strategy and outcome of infertility due to female genital tuberculosis (GTB) diagnosed with the help of a simplified tuberculosis (TB) algorithm. DESIGN: Data from 150 women with infertility (Group I) and 47 women with general gynaecological problems (Group II) were analysed. RESULTS: GTB was diagnosed in 7.2% of Group I and 2.8% of Group II women. Anti-tuberculosis treatment resulted in resolution of symptoms other than infertility in over 90% of cases. Of the total 20 pregnancies in the group, 10 were obtained in 32 IVF treatment patients. CONCLUSIONS: A definitive bacteriological diagnosis was generally difficult to achieve in GTB before administration of anti-tuberculosis treatment. A high index of suspicion and several other morphological and/or laboratory criteria were employed. It is suggested that a step-wise algorithm can help in the management of these cases. 相似文献
2.
R Guleria Y K Batra B K Sharma S K Jindal 《The Indian journal of chest diseases & allied sciences》1992,34(3):149-152
A patient of chronic obstructive pulmonary disease (COPD) with cor-pulmonale and chronic respiratory failure, who was given intermittent positive pressure ventilation at home, is reported. The patient did remarkably well on home mechanical ventilatory support. We believe this to be the first case report of domiciliary mechanical ventilation in a patient of COPD from India. 相似文献
3.
4.
K. S. Kohli D. V. Rai P. Kumar V. K. Jindal Dr. N. Goyal 《Medical & biological engineering & computing》1997,35(4):348-353
The complex electrical impedance of a goat eye lens is studied in the frequency range 10mHz−10Hz at room temperature, using
a computer-controlled AC impedance system. AC impedance software (model 368, version 2.2) is employed to determine the total
impedance and capacitance of the eye lens at various frequencies. A Cole-Cole plot of the eye lens material is drawn between
the real component of impedance Z′ and the imaginary component Z″ for each excitation frequency that shows a perfect arc of
a semicircle, with its centre lying below the abscissa at an angle of 35°. The half-angle ϕ between R0 and R∞ is found to be 55°, which mathematically demonstrates the selective permeability of the eye lens. Using graphical analysis
of the Cole-Cole plot, characteristic frequency fc and distribution factor α are observed to be 1Hz and 0.77, respectively. At characteristic frequency, capacitance and total
impedance are found to be 1.14μF and 9.08kΩ. The effect of electrode polarisation on capacitance is corrected, based on Fricke's
power function. The observed electrical parameters are then used to explain the multiple current path through various tissue
compartments. Further, an attempt is made to explain the results on the basis of a possible dipolar model. 相似文献
5.
Mathur SK Singh S Marwah N Jindal R Arora B Rattan KN 《Indian journal of pathology & microbiology》2004,47(2):261-263
Pancreatoblastoma or infantile pancreatic carcinoma is a rare pancreatic tumor with distinct acinar and squamoid cell differentiation that generally affects infants and young children. Ultrasound and CT scan may be useful but preoperative diagnosis is often quite difficult. The outcome is generally favourable. A such case of 10 years old boy with an abdominal mass is being presented. 相似文献
6.
K. S. Kohli Dr. D. V. Rai V. K. Jindal N. Goyal 《Medical & biological engineering & computing》1998,36(5):604-607
A computer assisted AC impedance system is used to measure the DC voltage—current (V-I) characteristics and AC impedance of
a goat eye lens using a two-probe Ag−AgCl electrode system. The measurement of the V-I characteristics shows that when a DC
voltage from 0mV to 30mV is applied, the resultant current decreases from an initial value of 0.58μA to 0.006μA. However,
when the voltage is increases beyond 30mV, the current increases and reaches a value of 0.9μA at 100mV. The data on the frequency
response (0.01–10 Hz) of the impedance of lens tissue show an inverse relationship with frequency. The effect of various DC
voltages, namely 0, 30, 50, 100 and 200 mV, on the impedance of the eye lens is also investigated over a frequency range of
0.01–10 Hz. The measurement results for both V-I characteristics and AC impedance further suggest the presence of a 30 mV
voltage compartment in the goat eye lens. 相似文献
7.
A K Deshpande G D Jindal I P Babu S N Nerurkar M D Kelkar G B Parulkar 《Journal of postgraduate medicine》1990,36(2):80-82
Impedance plethysmographic observations have been correlated with aortographic observations in 57 patients suspected of aortic occlusive diseases. Aortic occlusions have been characterised by marked decrease in blood flow index and significant increase in differential pulse arrival time at thigh level bilaterally. Atherosclerotic affection of the aorta has been featured by a bilateral decrease in the value of blood flow index as well as differential pulse arrival time at thigh level. Leriche's syndrome, however, has been found to decrease the blood flow index moderately at thigh in both the legs without any significant change in differential pulse arrival time. Aortography in all the patients has confirmed the diagnosis made by impedance plethysmography. 相似文献
8.
A study of 190 children of chronic cervical lymphadenitis showed tuberculous etiology on histopathological examination in 92 (48.4%) and bacteriological evidence of mycobacterial infection (smear and/or culture) in 42 (22.1%). Of these 42, twelve (28.6%) showed histopathological diagnosis of non-specific lymphadenitis. Positive culture for mycobacteria was obtained in 40, of which 30 (75%) were typical M. tuberculosis and 10 (25%) were atypical mycobacteria. The most predominant species of typical mycobacteria was M. scrofulaceum (60%) followed by M. avium intracellulare (40%). There was no remarkable difference in the histopathological pattern of those in which M. tuberculosis was grown and those in which bacterial growth was that of atypical mycobacteria. The diagnosis of chronic cervical lymphadenitis should therefore be taken a step beyond histopathology, up to complete bacteriological examination, especially to confirm the cases of mycobacterial lymphadenitis caused by atypical mycobacteria. 相似文献
9.
Disease association of antibodies to human and mycobacterial hsp70 and hsp60 stress proteins. 下载免费PDF全文
A Elsaghier C Prantera G Bothamley E Wilkins S Jindal J Ivanyi 《Clinical and experimental immunology》1992,89(2):305-309
Structural homology between microbial and human stress proteins has been postulated to be a basis for autoimmunization in chronic inflammatory diseases. Therefore, we estimated by ELISA titration the antibody levels to mycobacterial (M) and human (H) recombinant hsp70 and M-hsp65 heat-shock proteins in sera of patients with Crohn's disease (n = 29), ulcerative colitis (n = 20) and nontuberculous mycobacterial disease of the lungs (n = 20). Antibodies to H-hsp60, separated by two-dimensional gel electrophoresis, were tested in six sera of each group of patients. In Crohn's disease, antibody titres to the M-hsp65 antigen without detectable H-hsp60 binding were significantly elevated in 52% of the patients. In contrast titres to both M-hsp70 and H-hsp70 were demonstrable and correlated, but increased over control values only in four (14%) patients. The antibody pattern in ulcerative colitis was found to be quite different: anti-H-hsp60 binding was demonstrable in most patients, although anti-M-hsp65 titres were not elevated. Furthermore, 25% of patients had significantly elevated titres to M-hsp70, but not to H-hsp70. In non-tuberculous mycobacterial pulmonary disease, about 50% of patients had elevated titres to both hsp65 and hsp71 mycobacterial antigens but not to the corresponding human proteins; patients with Mycobacterium xenopi infection had the highest titres in this group. These results demonstrate the existence of distinct disease-associated patterns in the human antibody response to stress protein antigens. However, these data are not sufficient to imply sensitization with mycobacteria in patients with inflammatory bowel diseases, since certain epitopes of heat-shock proteins are shared by several bacterial genera. 相似文献
10.
Talreja J Bhatnagar A Jindal SK Ganguly NK 《Clinical and experimental immunology》2003,131(2):292-298
Host defence against tuberculosis infection involves T-lymphocyte mediated cellular immune responses. In this study we assessed T-cell activation by studying the early signal transduction events and production of cytokines by human CD4+ T-cells. The study constituted of five groups of subjects: (a) untreated acid fast bacilli (AFB)+ve TB patients who have not started anti-tuberculosis therapy (ATT) [New]; (b) patients who have taken ATT for two months [2T]; (c) patients who have taken ATT for six months [6T]; (d) mantoux positive healthy controls [T+ve]; (e) mantoux negative healthy controls [T-ve]. We found that mantoux positive healthy controls produced significantly higher levels of IP3, intracellular Ca2+ and presented increased PKC activity when CD4+ T-cells were stimulated with M. tuberculosis H37Rv cell lysate as compared to mantoux negative controls. Furthermore, decreased expression of CD54 (ICAM-1) and reduced [Ca2+]i were seen in TB patients as compared to T+ve healthy controls. TB patients showed significantly lower levels of IL-2 and IFNgamma and higher levels of IL-4 as compared to normal healthy controls, suggesting a diminished Th1 response. Thus, the reciprocal changes in cytokines, reduced [Ca2+]i levels, and CD54 expression in patients imply phenotype shifting of Th precursors to Th2 type in TB patients. 相似文献