全文获取类型
收费全文 | 435篇 |
免费 | 34篇 |
专业分类
耳鼻咽喉 | 23篇 |
儿科学 | 22篇 |
妇产科学 | 8篇 |
基础医学 | 58篇 |
口腔科学 | 4篇 |
临床医学 | 36篇 |
内科学 | 133篇 |
皮肤病学 | 18篇 |
神经病学 | 16篇 |
特种医学 | 12篇 |
外科学 | 49篇 |
综合类 | 11篇 |
预防医学 | 12篇 |
眼科学 | 8篇 |
药学 | 51篇 |
肿瘤学 | 8篇 |
出版年
2023年 | 3篇 |
2021年 | 3篇 |
2019年 | 5篇 |
2018年 | 12篇 |
2017年 | 11篇 |
2016年 | 9篇 |
2015年 | 12篇 |
2014年 | 12篇 |
2013年 | 13篇 |
2012年 | 21篇 |
2011年 | 11篇 |
2010年 | 20篇 |
2009年 | 18篇 |
2008年 | 17篇 |
2007年 | 15篇 |
2006年 | 22篇 |
2005年 | 21篇 |
2004年 | 8篇 |
2003年 | 15篇 |
2002年 | 24篇 |
2001年 | 20篇 |
2000年 | 14篇 |
1999年 | 29篇 |
1998年 | 11篇 |
1997年 | 15篇 |
1996年 | 15篇 |
1995年 | 6篇 |
1994年 | 12篇 |
1993年 | 7篇 |
1992年 | 15篇 |
1991年 | 6篇 |
1990年 | 7篇 |
1988年 | 2篇 |
1987年 | 2篇 |
1986年 | 2篇 |
1984年 | 3篇 |
1983年 | 2篇 |
1981年 | 1篇 |
1980年 | 2篇 |
1977年 | 2篇 |
1976年 | 1篇 |
1975年 | 1篇 |
1967年 | 2篇 |
1964年 | 1篇 |
1962年 | 2篇 |
1959年 | 3篇 |
1958年 | 3篇 |
1957年 | 1篇 |
1955年 | 3篇 |
1954年 | 5篇 |
排序方式: 共有469条查询结果,搜索用时 0 毫秒
1.
2.
Laparoscopic surgery has several advantages over traditional surgery because it has been shown to be less invasive. The next logical step in the evolution of minimally invasive surgery may be to eliminate all abdominal incisions. The natural orifices provide a port of entry via the gastrointestinal tract to the peritoneal cavity. This approach would require the creation of a perforation, which is considered to be a major complication of endoscopy with significant morbidity and mortality. However, there are several recent studies that have described the technical feasibility and safety of a per‐oral transgastric approach to the peritoneal cavity using conventional endoscopes. Theoretically, this approach could reduce postoperative abdominal wall pain, wound infection, hernia formation, and adhesions. This article aims to summarize the current status of transgastric surgery, currently referred to as natural orifice transluminal endoscopic surgery (NOTES), and to address some of its future challenges. 相似文献
3.
4.
A Golz S T Westerman L M Gilbert H Z Joachims A Netzer 《The Journal of laryngology and otology》1991,105(12):987-989
Although middle ear effusion was once described as the most common cause of vestibular disturbance in children, the association between glue ear and symptoms of dysequilibrium has never been quantified objectively. In this study the effect of middle ear effusion on the vestibular system of the inner ear was studied in a select group of children suffering from long lasting effusion in the middle ear with no evidence of infection at least one year prior to the study. The results were compared with results obtained from otitis free children, as well as from examinations of children after the insertion of ventilating tubes. The results of this study confirm the assumption that middle ear effusion has an adverse effect on the vestibular system, which can be resolved following the insertion of ventilation tubes. This effect may also contribute to the adverse effect that otitis media has on a child's development. 相似文献
5.
D Ilfeld E Feierman O Kuperman S Kivity M Topilsky L Netzer M Pecht N Trainin 《Immunology》1984,53(3):595-598
We examined the effect of oral colchicine (1-2 mg/day) on four healthy volunteers' T cell subsets. Colchicine significantly (P less than 0.01) decreased the mean (+/- SD) percent of OKT3+ total T cells (from 70 +/- 16 to 47 +/- 13), OKT4+ helper/inducer T cells (from 44 +/- 9 to 24 +/- 6), and OKT8+ suppressor/cytotoxic T cells (from 27 +/- 7 to 17 +/- 7), but did not significantly affect the OKT4:OKT8 ratio (from 1.64 +/- 0.21 to 1.48 +/- 0.45) or concanavalin A-induced suppressor cell function (from 44 +/- 9% to 47 +/- 13%). Thus, colchicine non-selectively decreased the circulating helper/inducer and suppressor/cytotoxic T cells. 相似文献
6.
Rainer Netzer Pascal Pflimlin Gerhard Trube 《Pflügers Archiv : European journal of physiology》1994,426(3-4):206-213
The barium current through voltage-dependent calcium channels was recorded from cultured rat cortical neurons with the whole-cell configuration of the patch-clamp technique. The maximal current evoked by depolarising pulses from –80 mV to 0 mV was divided into inactivating and non-inactivating fractions. During the first minutes of whole-cell recording, the amplitude of the inactivating fraction increased from less than 0.1 nA to an average value of 1 nA, whereas the amplitude of the non-inactivating component remained essentially the same. This increase in amplitude was prevented when the perforated-patch technique was used, suggesting that some intracellular factor that inhibited the barium current was lost or destroyed during conventional whole-cell experiments. When GTP[-S] or GTP was added to the pipette solution, no increase or only a weak rise of the inactivating current was seen, whereas GDP[-S] accelerated its increase. The results suggest that some of the calcium channels expressed in cultured cortical neurons are inhibited by a G protein even in the absence of added neurotransmitter. The current increase observed during whole-cell recordings may be due to a loss of intracellular GTP and the subsequent inactivation of an inhibitory G protein. 相似文献
7.
S-A Ivarsson D Bergqvist NR Lundström E Maly KO Nilsson C Wattsgård 《Acta paediatrica (Oslo, Norway : 1992)》1992,81(12):1044-1048
We report a case of Takayasu's disease with severe renovascular hypertension in a girl from Eritrea. In the "burn-out" phase after the erythrocyte sedimentation rate had normalized, reconstructive vascular surgery was performed as further progression of the disease seemed unlikely. However, probably due to her growth, the graft rotated and a second operation was successfully performed. 相似文献
8.
9.
10.