全文获取类型
收费全文 | 9880篇 |
免费 | 546篇 |
国内免费 | 40篇 |
专业分类
耳鼻咽喉 | 40篇 |
儿科学 | 185篇 |
妇产科学 | 183篇 |
基础医学 | 1313篇 |
口腔科学 | 447篇 |
临床医学 | 825篇 |
内科学 | 2682篇 |
皮肤病学 | 255篇 |
神经病学 | 995篇 |
特种医学 | 300篇 |
外科学 | 1205篇 |
综合类 | 26篇 |
一般理论 | 2篇 |
预防医学 | 460篇 |
眼科学 | 131篇 |
药学 | 562篇 |
中国医学 | 27篇 |
肿瘤学 | 828篇 |
出版年
2024年 | 8篇 |
2023年 | 73篇 |
2022年 | 156篇 |
2021年 | 292篇 |
2020年 | 160篇 |
2019年 | 231篇 |
2018年 | 277篇 |
2017年 | 218篇 |
2016年 | 227篇 |
2015年 | 280篇 |
2014年 | 396篇 |
2013年 | 483篇 |
2012年 | 777篇 |
2011年 | 795篇 |
2010年 | 414篇 |
2009年 | 377篇 |
2008年 | 660篇 |
2007年 | 671篇 |
2006年 | 596篇 |
2005年 | 645篇 |
2004年 | 557篇 |
2003年 | 498篇 |
2002年 | 479篇 |
2001年 | 101篇 |
2000年 | 87篇 |
1999年 | 93篇 |
1998年 | 107篇 |
1997年 | 74篇 |
1996年 | 74篇 |
1995年 | 68篇 |
1994年 | 58篇 |
1993年 | 40篇 |
1992年 | 51篇 |
1991年 | 47篇 |
1990年 | 48篇 |
1989年 | 46篇 |
1988年 | 31篇 |
1987年 | 35篇 |
1986年 | 37篇 |
1985年 | 23篇 |
1984年 | 24篇 |
1983年 | 24篇 |
1982年 | 18篇 |
1981年 | 8篇 |
1980年 | 18篇 |
1979年 | 10篇 |
1976年 | 10篇 |
1974年 | 8篇 |
1970年 | 6篇 |
1968年 | 6篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Is it possible to make a diagnosis of raw,heated, and baked egg allergy in children using cutoffs? A systematic review 下载免费PDF全文
2.
A case of gastric tube bleeding after an Ivor-Lewis esophagectomy with gastroesophageal anastomosis is reported. During the early postoperative course, the patient had a gastric tube stasis that improved progressively. The subsequent onset of a serious and intermittent hematemesis, which was endoscopically deemed to be the result of a hemorrhagic gastritis, required multiple blood transfusions. The evolution to a severe hemodynamic instability obliged us to reoperate on the patient. During surgery, a band-related obstruction of the first jejunal loop with local signs of vascular hypertension was noted. As soon as the obstruction was solved, the gastric bleeding stopped. The authors discuss the clinical aspects and physiopathology of the gastric tube bleeding and, in particular, they evaluate the influence of the intestinal obstruction with vascular involvement on the development of this exceptional and severe complication. 相似文献
3.
Paula Vanessa Pedron Oltramari Ricardo de Lima Navarro José Fernando Castanha Henriques Rumio Taga Tania Mary Cestari Guilherme Janson José Mauro Granjeiro 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2007,104(5):e9-16
OBJECTIVE: The objective of this study was to radiographically quantify bone density and bone height preservation in tooth extraction alveolus filled with xenograft. STUDY DESIGN: The maxillary and mandibular fourth deciduous molars and fourth premolars of 6 minipigs were removed. Randomly, in 3 animals the right side was used as the test side and in the other 3 animals the left side was the test side. Intraoral radiographs were performed to compare the condition at the initial time and 3 months later. Measurements of bone height and bone density were performed using KS300 (Zeiss) software. RESULTS: After 3 months, there was a statistically significant smaller bone height loss for the test group. The test group presented a statistically greater bone density immediately after tooth extraction. However, after 3 months there was no statistically significant difference between the groups. CONCLUSIONS: The results suggest that treatment of postextraction alveolus with xenograft can preserve bone height initially but differences in bone density compared to when no xenograft is used are not sustained. 相似文献
4.
Angelo M. Carella Sandro Nati Paolo Carlier Daniela Pierluigi Domenico Giordano Angela Congiu Gino Santini Daniele Scarpati Salvina Barra Renzo Corvo Vito Vitale Maria R. Raffo Raffaella Cerri Marco Risso Mauro Spriano Renato Vimercati Ester Pungolino Andrea Bacigalupo Eugenio Damasio 《Leukemia & lymphoma》1991,5(1):43-47
Forty consecutive adult patients under the age of 50 with acute non-lymphoblastic leukemia (ANLL) in first complete remission, underwent autologous bone marrow transplantation (ABMT) between March 1984 and April 1990. The conditioning regimen employed included cyclophosphamide and total body irradiation, followed by the administration of unpurged ABMT. The median time from diagnosis to transplant was 7 months (3-15 months), and the median time from complete remission to ABMT was 4 months (range 3-9 months). Twenty-two (51%) patients remain in complete remission 6-81 months (median 24 months) after ABMT.
The causes of death were, recurrent leukemia (11 patients), parenchymal toxicities such as acute respiratory distress syndrome and veno-occlusive disease (3 patients), hemorrhage (2 patients) and infection (2 patients). Eleven patients relapsed after 3-12 months (median 5 months). This study has produced survival data comparable to those of other institutions employing TBI for either allo or autotransplants. 相似文献
The causes of death were, recurrent leukemia (11 patients), parenchymal toxicities such as acute respiratory distress syndrome and veno-occlusive disease (3 patients), hemorrhage (2 patients) and infection (2 patients). Eleven patients relapsed after 3-12 months (median 5 months). This study has produced survival data comparable to those of other institutions employing TBI for either allo or autotransplants. 相似文献
5.
An early accurate diagnosis of subungual melanoma depends upon an alert podiatric physician. Clinically, the lesion is often easily misdiagnosed and mistreated because of its resemblance to benign nail conditions. This paper discusses the incidence, histology, clinical findings, diagnosis, and treatment of this malignant lesion. An illustrative case report is presented. 相似文献
6.
Fernanda Martini Alfredo Corallini Veronica Balatti Silvia Sabbioni Cecilia Pancaldi Mauro Tognon 《Infectious agents and cancer》2007,2(1):13-12
Simian virus 40 (SV40) is a monkey virus that was administered to human populations by contaminated vaccines which were produced
in SV40 naturally infected monkey cells. 相似文献
7.
Alfredo Marzano Silvia Gaia Valeria Ghisetti Silvia Carenzi Alberto Premoli Wilma Debernardi-Venon Carlo Alessandria Alessandro Franchello Mauro Salizzoni Mario Rizzetto 《Liver transplantation》2005,11(4):402-409
Hepatitis B virus (HBV) recurrence after liver transplantation is significantly reduced by prophylaxis with hepatitis B immune globulins (HBIG) or antiviral drugs in nonreplicating patients and by the combination of both drugs in replicating patients. However, the load of HBV DNA, which defines replicating status in patients undergoing liver transplantation, remains unclear. This study analyzes the correlation between the viral load, tested with a single amplified assay, at the time of liver transplantation, and the risk of hepatitis B recurrence in 177 HBV carriers who underwent transplantation in a single center from 1990 to 2002. Overall, HBV relapsed after surgery in 15 patients (8.5%) with a 5- and 8-year actuarial rate of recurrence of 8% and 21%, respectively. After liver transplantation hepatitis B recurred in 9% of 98 selected subjects treated only with immune globulins and in 8% of 79 viremic patients who received immune globulins and lamivudine (P = NS). A linear correlation was observed between recurrence and viral load at the time of surgery. In transplant patients with HBV DNA higher than 100,000 copies/mL, 200-99,999 copies/mL, and DNA undetectable by amplified assay, hepatitis B recurred in 50%, 7.5%, and 0% of patients, respectively. Overall, a viral load higher than 100,000 copies/mL at the time of liver transplantation was significantly associated with hepatitis B recurrence (P = .0003). In conclusion, spontaneous or antiviral-induced HBV DNA viral load at the time of surgery classifies the risk of HBV recurrence after liver transplantation and indicates the best prophylaxis strategy. 相似文献
8.
Salvatore Serra Giuliana Brunetti Giovanni Vacca Carla Lobina Mauro A M Carai Gian Luigi Gessa Giancarlo Colombo 《Alcohol》2003,29(2):101-108
Results of a recent study have demonstrated that exposure to multiple ethanol concentrations and repeated ethanol deprivation periods in Indiana ethanol-preferring (P) rats resulted in the development of an alcohol deprivation effect (ADE; the temporary increase in voluntary ethanol intake after a period of deprivation from ethanol) characterized by consumption of intoxicating amounts of ethanol. The current study was designed to possibly extend these results to Sardinian alcohol-preferring (sP) rats, generated with the same selective program previously used for P rats. To this aim, ethanol-naive sP rats were exposed initially to the home cage four-bottle choice [10%, 20%, and 30% (vol./vol.) ethanol solutions and water] for eight consecutive weeks. Subsequently, rats were divided into two groups: The first group had continuous access to the four-bottle regimen (nondeprived rats), and the second group was exposed to five cycles of 14-day periods of deprivation from ethanol and 14-day periods of reexposure to the four-bottle regimen. An ADE developed after each deprivation period. However, the extra intake of ethanol was limited to the first hour of each reaccess period. Magnitude of ADE did not change with repeated periods of deprivation. However, a shift in preference toward the two highest concentrations of ethanol solutions was evident from the first reexposure to ethanol and was maintained throughout the study. These results provide further evidence on the heterogeneity of ethanol-drinking behavior among rat lines selectively bred for high ethanol preference and consumption. 相似文献
9.
Photocarcinogenesis and inhibition of intercellular adhesion molecule 1 expression in cells of DNA-repair-defective individuals 下载免费PDF全文
10.
Stefano Miceli Sopo Daniele Radzik Mauro Calvani 《Pediatric allergy and immunology》2007,18(7):575-582
Investigators have tried to identify a level of seric specific immunoglobulin E (IgE) that had a sufficient predictive value to diagnose a food allergy without having will resort to the food challenge. To search in literature, all the studies that have estimated the possibility to identify a level of seric specific cow milk IgE with a positive predictive value (PPV) of 95% for the first diagnosis of cow's milk allergy (CMA) in pediatric age. We have identified six studies, nearly all studies suffer from relevant methodological bias. Proposed cut-off are all different. The studied pediatric populations were highly selected. Also neglecting the methodological bias of the studies and the great difference of value between the proposed cut-off, it always remains to consider that the pre-test probability of having a CMA between the children enrolled in the six studies included in this review is particularly high. The likelihood ratio helps to transfer the results of a study on a diagnostic test just to our population, and it is more realistic rather than to entrust itself to the PPV or the negative predictive value, that are much influenced from the prevalence of the disease in the studied population. 相似文献