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排序方式: 共有550条查询结果,搜索用时 15 毫秒
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2.
N Nagae T Watanabe M Miura T Minowa S Hirooka M Washio 《Kyobu geka. The Japanese journal of thoracic surgery》1990,43(10):830-834
This case report was with regard to familial heparin cofactor II (HC II) deficiency. The patient was a 14-years-old female, having complaints of chest pain, fever and swelling of right lower extremity. Echocardiography and DSA showed a pediculated mass at the right ventricular outflow tract which highly suggested a ventricular myxoma. At surgery, a large pediculated thrombus was removed from the RV conus septum aun pulmonary valve. The mass was identified as thrombus by histological examination. Two months later, the RV thrombi recurred with additional pulmonary embolus to the left lung. HC II was discovered by hemo-coagulation tests. Her HC II antigen value was 48%, and 32% on repeat study. Her brother's HC II antigen value was 53%. At reoperation, small thrombi less than phi 10 mm, were removed from the RV outflow tract and pulmonary valve. Fresh frozen plasma was given and intravenous urokinase therapy was taken. She is doing well with therapy of oral warfarin, aspirin and ticlopidine for anticoagulation. 相似文献
3.
2 embryos, 4 youngs, 4 older youngs and the pouch of 2 mothers of the red kangaroos were examined. The results obtained are as follows: 1. The initial muscle spindles are already observed light microscopically in the vertebral, dorsal neck and forelimb muscles of the newborn baby and a little bit later in the masticatory muscles of the young of 68 mm in craniorump length and 28 g in body weight. 2. In the skin with less hair lining the inner surface of the pouch, abundant apocrine large sweat glands are observed, especially surrounding the basal region of the nipple and in the pleat formation of the skin. 3. The lactiferous mammary gland is enlarged, the lobules being divided by the interlobular muscle fiber tissue and enwrapped by the muscular capsule. The milk is squirted automatically by the muscle fiber contraction from the gland to the nipple, to which the baby attaches itself. 4. The musculature of the pouch wall is developed to form the sphincter muscle in the pouch orifice. The sphincter muscle plays an important role in conditioning the optimum temperature for the naked baby inside the pouch. 5. The apocrine perfume plays an important role in guiding the baby on the journey to the pouch after birth and the apocrine products also in maintaining the optimum humidity of the pouch to accomodate the baby. 6. During the long period of stay in the pouch, the masticatory and locomotive systems and their neuromuscular mechanism related to the herbivorous mastication become fully established and then the young leaves the pouch to feed on the animal's proper diet. 相似文献
4.
Susumu Matsukuma Masateru Doi Masatoshi Suzuki Kazuya Ikegawa Kimiya Sato Noriyuki Kuwabara 《Pathology international》1997,47(11):789-793
A unique case of duodenal stromal tumor In a 51-year-old man is reported. The tumor histologically showed spindle cell proliferation and numerous eosinophilic globules. Most globules were composed of tangled 45 nm thick fibrils, which were ultrastructurally Identical to 'skelnoid fibers'. The presence of glycogen granules in the tumor cells and the Immunoreactivity for α-smooth muscle actin suggested smooth muscle differentiation. Focal ultrastructural findings also supported the smooth muscle nature of this tumor. There were no immunohistochemical and ultra-structural features indicating neural differentiation. In previous studies, the presence of such 'skeinoid fibers' was suggested to be a histological marker for neural differentiation in gastrointestinal stromal tumor. However, the findings In the present case suggest that numerous 'skeinoid fibers' can be Identified in duodenal stromal tumor with smooth muscle differentiation, although this condition may be rare. 相似文献
5.
Mochizuki Toshio Muto Satoru Miyake Masateru Tanaka Toshiki Wang Wenchyi 《Clinical and experimental nephrology》2021,25(11):1231-1239
Clinical and Experimental Nephrology - Tolvaptan is a vasopressin type 2 receptor antagonist and has been used to treat autosomal dominant polycystic kidney disease (ADPKD) since 2014. There has... 相似文献
6.
Viroonchatapan Ekapop Ueno Masaharu Sato Hitoshi Adachi Isao Nagae Hideo Tazawa Kenji Horikoshi Isamu 《Pharmaceutical research》1995,12(8):1176-1183
Purpose. Dextran magnetite (DM)-incorporated thermosensitive liposomes, namely thermosensitive magnetoliposomes (TMs), were prepared and characterized in order to investigate their possibility for magnetic drug targeting.
Methods. TMs containing calcein were prepared at various DM concentrations by reverse-phase evaporation of dipalmitoylphosphatidylcholine (DPPC). They were evaluated for their physicochemical properties including size, DM capture, magnetite distribution within liposomes, and temperature-dependent calcein release. Moreover, a novel on-line flow apparatus with a sample injector, a coil of tubing placed in an electromagnet, and a fluorescence detector was developed for quantifying the magnetic responsiveness of TMs. This device allowed us a real-time measurement of percentage holding of TMs by magnetic field.
Results. Due to water-soluble property of DM, higher contents of magnetite up to 490 mg per mmol DPPC were successfully incorporated into the liposomes with DM than with conventional magnetite (Fe3O4). Thermosensitivity and lipid integrity of TMs were not influenced by inclusion of DM. Using the on-line flow system, percentage holding of TMs by magnetic field was shown to vary with several factors; it increases as the magnetic field strength increases, the fluid flow rate decreases, the magnetite content increases, and the liposome concentration increases. Typically, at 490 mg incorporated magnetite per mmol DPPC, 0.5 ml/min-fluid flow rate, and high magnetic field strength (10 kiloGauss), approximately 100% of TMs were found to be held.
Conclusions. The TMs were suggested to be useful in future cancer treatment by magnetic targeting combined with drug release in response to hyperthermia. 相似文献
7.
Age‐ and sex‐associated morphological variations of metatarsal torsional patterns in humans
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Masateru Kitashiro Naomichi Ogihara Tetsuro Kokubo Morio Matsumoto Masaya Nakamura Takeo Nagura 《Clinical anatomy (New York, N.Y.)》2017,30(8):1058-1063
It has been demonstrated that the torsional patterns of the metatarsal heads are associated with the presence or absence of the medial longitudinal arch in hominoid feet. The relatively untwisted second metatarsal is unique in humans, but that of the African apes is much more inverted, suggesting that the torsion of the second metatarsal might represent the overall shape and flatness of the foot. Some clinical studies have recently argued that the onset of foot pathologies such as hallux valgus might be related to the torsional pattern of the metatarsals. However, to date, no studies have systematically investigated the morphological variations of the torsional patterns of human metatarsals. In this study, therefore, the aim was to clarify the age‐ and sex‐associated variations in the torsional patterns of human metatarsals using three‐dimensional computed tomography. The torsion angles of the five metatarsals were calculated by defining the dorsopalmar vector of the metatarsal base and the vector corresponding to the rotational axis of the metatarsal head. The present result demonstrated that the second metatarsals of females were significantly more inverted with increasing age. Flat foot is known to be most common in elderly women. Whether there is a cause–effect relationship between second metatarsal torsion and flattening of the medial longitudinal arch has yet to be answered, but this study suggested that torsion of the second metatarsal might possibly be used as an indicator for the early diagnosis of flat foot and associated foot pathologies. Clin. Anat. 30:1058–1063, 2017. © 2017 Wiley Periodicals, Inc. 相似文献
8.
Masateru Takigawa Jatin Relan Ruairidh Martin Steven Kim Takeshi Kitamura Antonio Frontera Ghassen Cheniti Konstantinos Vlachos Grégoire Massoullié Claire A. Martin Nathaniel Thompson Michael Wolf Felix Bourier Anna Lam Josselin Duchateau Nicolas Klotz Thomas Pambrun Arnaud Denis Pierre Jaïs 《Heart rhythm》2018,15(12):1853-1861
9.
Iwakawa Hidehiro Takigawa Masateru Goya Masahiko Iwata Toyoto Martin Claire A. Anzai Tatsuhiko Takahashi Kunihiko Amemiya Miki Yamamoto Tasuku Sekigawa Masahiro Shirai Yasuhiro Tao Susumu Hayashi Tatsuya Takahashi Yoshihide Watanabe Hiroyuki Sasano Tetsuo 《Journal of interventional cardiac electrophysiology》2022,63(1):185-195
Journal of Interventional Cardiac Electrophysiology - Clinical implication of local impedance (LI) for radiofrequency (RF) ablation has not been fully established. This study aimed to investigate... 相似文献
10.
Ultralow temperature cryoablation: Safety and efficacy of preclinical atrial and ventricular lesions
Felix Bourier MD Masateru Takigawa MD PhD Anna Lam MD Konstantinos Vlachos MD F. Daniel Ramirez MD MSc Claire A. Martin MD Antonio Frontera MD PhD Takeshi Kitamura MD Josselin Duchateau MD Thomas Pambrun MD Nicolas Derval MD Arnaud Denis MD Jerry Cox MD David Cabrita MD Alexander Babkin PhD Marion Constantin MA Pierre Jais MD Frédéric Sacher MD PhD Rémi Dubois MD PhD Oliver Bernus PhD Michel Haissaguerre MD Mélèze Hocini MD 《Journal of cardiovascular electrophysiology》2021,32(3):570-577