全文获取类型
收费全文 | 9316篇 |
免费 | 873篇 |
国内免费 | 47篇 |
专业分类
耳鼻咽喉 | 114篇 |
儿科学 | 313篇 |
妇产科学 | 219篇 |
基础医学 | 1440篇 |
口腔科学 | 248篇 |
临床医学 | 786篇 |
内科学 | 2082篇 |
皮肤病学 | 244篇 |
神经病学 | 963篇 |
特种医学 | 331篇 |
外国民族医学 | 1篇 |
外科学 | 1318篇 |
综合类 | 49篇 |
一般理论 | 1篇 |
预防医学 | 715篇 |
眼科学 | 131篇 |
药学 | 624篇 |
中国医学 | 19篇 |
肿瘤学 | 638篇 |
出版年
2023年 | 52篇 |
2022年 | 116篇 |
2021年 | 235篇 |
2020年 | 155篇 |
2019年 | 243篇 |
2018年 | 308篇 |
2017年 | 211篇 |
2016年 | 233篇 |
2015年 | 248篇 |
2014年 | 300篇 |
2013年 | 419篇 |
2012年 | 538篇 |
2011年 | 538篇 |
2010年 | 336篇 |
2009年 | 262篇 |
2008年 | 429篇 |
2007年 | 429篇 |
2006年 | 453篇 |
2005年 | 412篇 |
2004年 | 376篇 |
2003年 | 310篇 |
2002年 | 324篇 |
2001年 | 317篇 |
2000年 | 302篇 |
1999年 | 251篇 |
1998年 | 104篇 |
1997年 | 104篇 |
1996年 | 95篇 |
1995年 | 99篇 |
1994年 | 75篇 |
1993年 | 55篇 |
1992年 | 206篇 |
1991年 | 176篇 |
1990年 | 164篇 |
1989年 | 166篇 |
1988年 | 151篇 |
1987年 | 115篇 |
1986年 | 108篇 |
1985年 | 106篇 |
1984年 | 96篇 |
1983年 | 65篇 |
1982年 | 42篇 |
1981年 | 32篇 |
1980年 | 32篇 |
1979年 | 61篇 |
1978年 | 33篇 |
1977年 | 31篇 |
1974年 | 40篇 |
1973年 | 34篇 |
1971年 | 31篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
Luis Veloza Cristina Teixido Natalia Castrejon Fina Climent Ana Carri Marta Marginet Davide Soldini Blanca Gonzlez‐Farr Inmaculada Ribera‐Cortada Armando Lopez‐Guillermo Eva Gonzlez‐Barca Adriana Sierra Mileyka Herrera Cndida Gmez Adriana Garcia Olga Balagu Elias Campo Antonio Martinez 《Histopathology》2019,75(6):799-812
3.
Phenotypic and genetic features of enteropathogenic Escherichia coli isolates from diarrheal children in the Ribeirão Preto metropolitan area,São Paulo State,Brazil 下载免费PDF全文
André Pitondo‐Silva Gerson Nakazato Juliana P. Falcão Kinue Irino Roberto Martinez Ana Lúcia C. Darini Rodrigo Tavanelli Hernandes 《APMIS : acta pathologica, microbiologica, et immunologica Scandinavica》2015,123(2):128-135
This study was designed to characterize a collection of 60 enteropathogenic Escherichia coli (EPEC) isolates from diarrheic feces of patients in the Ribeirão Preto metropolitan area regarding different phenotypic and molecular features. We examined antibiotic resistance profiles, occurrence of virulence factors‐encoding genes, intimin subtypes and the correlation of serotypes among typical (tEPEC) and atypical (aEPEC) EPEC isolates. The results demonstrated that atypical EPEC was more heterogeneous than typical EPEC concerning the characteristics investigated and 45.2% do not belong to classical EPEC serogroups. Intimin subtype β was the most frequent among the EPEC isolates (46.7%), being detected in both tEPEC and aEPEC. The majority of aEPEC isolates presented localized adherence‐like (LAL) pattern to HEp‐2 cells, although aEPEC isolates displaying diffuse adherence (DA) or non‐adherent were also detected. High prevalence of antimicrobial resistance was found for ampicillin, cephalothin, sulfonamide and tetracycline. In general, tEPEC isolates were more resistant to the antimicrobials tested than aEPEC isolates. 相似文献
4.
5.
6.
Nicolas Pallet Eric Thervet Corinne Alberti Violaine Emal-Aglaé Janine Bedrossian Frank Martinez Carine Roy Christophe Legendre 《American journal of transplantation》2005,5(11):2682-2687
Despite recent improvement, significant racial disparities in outcome still persist after renal transplantation among African American patients in the United States. This study evaluated the association of race and ethnicity with allograft outcomes in a French population of 952 Caucasian (Cauc) patients and 140 African European (AE) patients who underwent renal transplantation in our center between 1987 and 2003. Demographic characteristics were similar for the two cohorts other than cause of end-stage renal failure (more hypertension among AE and more polycystic kidney disease among Cauc) and cold ischemia time (significantly longer for AE). Immunosuppressive treatment was comparable between groups. There were no significant differences between AE and Cauc in the incidence of acute rejection (31% vs. 30%). At 5 years post-transplant, patient survival (93% vs. 92%), graft survival (83% in both groups) and graft function (creatinine clearance 48 mL/min vs. 45 mL/min) were also similar among the AE and Cauc patients. We demonstrate that ethnic origin does not affect outcome after renal transplantation in France. Therefore, differences observed in the United States cannot be only related to immunologic or pharmacologic factors. The results of renal transplantation in patients of African origin could be improved with universal immunosuppressive drug coverage. 相似文献
7.
J. Belchi-Hernandez S. Moreno-Grau F. Sánchez-Gascón J. Bayo B. Elvira Rendueles B. Bartolomé J. M. Moreno J. Martinez Quesada R. Palacios Peláez 《Allergy》1998,53(3):241-248
Zygophyllum fahago is a herbaceous plant found widely in the Mediterranean area. There are no previous reports of its allergenicity. An aerobiologic and clinical survey was conducted in Murcia, southern Spain, to determine the quantity of airborne pollen and establish the possible role of this pollen as a cause of allergic symptoms. With a Hirst volumetric trap, we determined the atmospheric concentrations of this pollen in 1993, 1994,1995, and 1996. Of 1180 patients tested, 181 (15,34%) had a positive skin test. To determine its allergenicity, we divided 47 patients into three groups: in group 1, all the patients had symptoms of rhinoconjunctivitis plus asthma; in groups 2 and 3, rhinoconjunctivitis. In group 1, we performed a bronchial provocation test (BPT): in groups 2 and 3, we performed nasal provocation (NPT) and conjunctival provocation (CPT) tests, respectively, SDS-PAGE was used to characterize the antigenic fractions and RAST inhibition to determine cross-reactivity with other pollens. The pollen dispersion period is from May to September (445 grains/m3 ), BPT was positive in 13 of 15 patients, NPT in 14 of 16 patients, and CPT in 13 of 16 patients. RAST inhibition revealed cross-reactivity with Mercurialis, Ricinus, Olea. and Betula. SDS-PAGE identified 25 IgE antibody-binding components, five of which (60, 65, 41, 38, and 15.5/14,7 kDa) were recognized by 40% of the sera. By SDS-PAGE immunoblotting with sunflower antiprofilin rabbit serum and affinity chromatography we established that the Z. fahago extract has profilin. This study shows that this pollen becomes airborne and elicits an IgE response which triggers respiratory symptoms in allergic subjects. 相似文献
8.
Pyomyositis: characteristics at CT and MR imaging 总被引:9,自引:0,他引:9
9.
Prospective study of antigenemia,plasma viremia and lymphocytic viremia in HIV-infected hemophiliacs
S. Melón Garcia M. de Oña Navarro C. Rodriguez Pinto M. Fernández Urgellés A. Martinez Gutierrez P. de la Iglesia F. J. Mendez García 《European journal of clinical microbiology & infectious diseases》1995,14(5):400-405
A total of 186 blood samples from 24 HIV-1 seropositive hemophiliac patients, monitored every four months for 29 months, were investigated for the presence of viral antigen in plasma. In addition, peripheral blood mononuclear cells (PBMC) were cultured for HIV-1, using normal PBMC as a target for replication. Antigenemia was detected in 51 % of the patients and from PBMC in 87.5 % of the patients. The incidence of HIV isolation in asymptomatic patients (42.8 %) was similar to that found in symptomatic patients (51.4 %). Patients with opportunistic infections had a higher incidence of lymphocytic viremia (p<0.05). Plasma viremia was closely associated (p<0.05) with low CD4+ counts and infection progression. The persistence of antigenemia was also a marker of a poor clinical course. In treated patients, plasma viremia was the marker that better correlated with the clinical course, and it did not appear during the first nine months of therapy. Zidovudine doses of >500 mg/day significantly lowered the appearance of antigenemia and lymphocytic viremia (p<0.05). 相似文献
10.