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Alarms and Parameters Generated by Hematology Analyzer: New Tools to Predict and Quantify Circulating Sezary Cells 下载免费PDF全文
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Charlotte Dupont Celine Fauret Nathalie Sermondade Marouane Boubaya Florence Eustache Patrice Clement Pascal Briot Isabelle Berthaut Vincent Levy Isabelle Cedrin-Durnerin Brigitte Benzacken Pascale Chavatte-Palmer Rachel Levy 《Asian journal of andrology》2013,15(5):622-625
There has been a growing interest over the past few years in the impact of male nutrition on fertility. Infertility has been linked to male overweight or obesity, and conventional semen parameter values seem to be altered in case of high body mass index (BMI). A few studies assessing the impact of BMI on sperm DNA integrity have been published, but they did not lead to a strong consensus. Our objective was to explore further the relationship between sperm DNA integrity and BMI, through a 3-year multicentre study. Three hundred and thirty male partners in subfertile couples were included. Using the terminal uridine nick-end labelling (TUNEL) assay, we observed an increased rate of sDerm DNA damage in obese men (odds ratio (95% confidence interval): 2.5 (1.2-5.1)). 相似文献
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Alaoui Amine Sanaâ Melloul Marouane El Alaoui Moulay Abdelaziz Boulahyaoui Hassan Loutfi Chafiqa Touil Nadia El Fahime Elmostafa 《Virus genes》2020,56(5):582-593
Virus Genes - Species A rotaviruses (RVAs) are a leading cause of diarrhea in children and in the young of a large variety of mammalian and avian host species. The purpose of this study was to... 相似文献
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Mechanical post-conditioning in STEMI patients undergoing primary percutaneous coronary intervention
Marouane Boukhris Radhouane Bousselmi Salvatore Davide Tomasello Zied Ibn Elhadj Salvatore Azzarelli Francesco Marzà Alfredo R. Galassi 《Journal of the Saudi Heart Association》2015,27(3):192-200
Although early myocardial reperfusion via primary percutaneous coronary intervention (PCI) allows the preservation of left ventricular function and improves outcome, the acute restoration of blood flow may contribute to the pathophysiology of infarction, a complex phenomenon called reperfusion injury. First described in animal models of coronary obstruction, mechanical post-conditioning, a sequence of repetitive interruption of coronary blood flow applied immediately after reopening of the occluded vessel, was able to reduce the infarct size. However, evidence of its real benefit remains controversial. This review describes the mechanisms of post-conditioning action and the different protocols employed focusing on its impact on primary PCI outcome. 相似文献
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Alaoui Amine Sanaâ Melloul Marouane El Alaoui Moulay Abdelaziz Touil Nadia El Fahime Elmostafa 《Virus genes》2019,55(4):465-478
Virus Genes - An unusual group A rotavirus (RVA) strain MAR/ma31/2011/G8P[14] was detected for the first time in Morocco in a stool sample from hospitalized child aged 18 months suffering... 相似文献
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Frédéric Pamoukdjian V. Lévy G. Sebbane M. Boubaya T. Landre C. Bloch-Queyrat E. Paillaud L. Zelek 《The journal of nutrition, health & aging》2017,21(2):202-206
Objective
To assess the predictive value of gait speed for early death in older outpatients with cancer.Design
Prospective bicentric observational cohort study.Setting
The Physical Frailty in Elder Cancer patients (PF-EC) study (France).Participants
One hundred and ninety outpatients with cancer during the first 6 months of follow up in the PF-EC study.Measurements
The association between usual gait speed over 4 m alone (GS) or included in the short physical performance battery (SPPB) and overall survival within 6 months following a comprehensive geriatric assessment (CGA). A Cox proportional-hazard regression model was performed in non-survivors for clinical factors from the CGA, along with c reactive protein (CRP). Two models were created to assess GS alone and from inclusion in the SPPB.Results
The mean age was 80.6 years, and 50.5% of the participants were men. Death occurred in 11% (n=22) of the participants within the 6 month follow up period. Of these participants, 98% had solid cancers, and 33% had a metastatic disease. A GS < 0.8 m/s (HR=5.6, 95%CI=1.6-19.7, p=0.007), a SPPB < 9 (HR=5.8, 95%CI=1.6-20.9, p=0.007) and a CRP of 50 mg/l or greater (p<0.0001) were significantly associated with early death in the two multivariate analyses. Cancer site and extension were not significantly associated with early death.Conclusion
Walking tests are associated with early death within the 6 month follow up period after a CGA independent of cancer site and cancer extension. GS alone < 0.8 m/s is at least as efficacious as the SPPB in predicting this outcome. GS alone could be used routinely as a marker of early death to adapt oncologic therapeutics. Further studies are needed to validate these preliminary data.10.