全文获取类型
收费全文 | 3223篇 |
免费 | 194篇 |
国内免费 | 24篇 |
专业分类
耳鼻咽喉 | 37篇 |
儿科学 | 76篇 |
妇产科学 | 153篇 |
基础医学 | 422篇 |
口腔科学 | 75篇 |
临床医学 | 243篇 |
内科学 | 694篇 |
皮肤病学 | 57篇 |
神经病学 | 142篇 |
特种医学 | 98篇 |
外国民族医学 | 1篇 |
外科学 | 536篇 |
综合类 | 73篇 |
预防医学 | 274篇 |
眼科学 | 179篇 |
药学 | 236篇 |
中国医学 | 9篇 |
肿瘤学 | 136篇 |
出版年
2023年 | 21篇 |
2022年 | 83篇 |
2021年 | 144篇 |
2020年 | 58篇 |
2019年 | 90篇 |
2018年 | 105篇 |
2017年 | 85篇 |
2016年 | 86篇 |
2015年 | 84篇 |
2014年 | 140篇 |
2013年 | 170篇 |
2012年 | 201篇 |
2011年 | 239篇 |
2010年 | 129篇 |
2009年 | 118篇 |
2008年 | 154篇 |
2007年 | 156篇 |
2006年 | 134篇 |
2005年 | 141篇 |
2004年 | 115篇 |
2003年 | 98篇 |
2002年 | 84篇 |
2001年 | 65篇 |
2000年 | 70篇 |
1999年 | 53篇 |
1998年 | 19篇 |
1997年 | 16篇 |
1996年 | 21篇 |
1995年 | 15篇 |
1994年 | 17篇 |
1993年 | 14篇 |
1992年 | 54篇 |
1991年 | 50篇 |
1990年 | 47篇 |
1989年 | 49篇 |
1988年 | 29篇 |
1987年 | 29篇 |
1986年 | 34篇 |
1985年 | 30篇 |
1984年 | 24篇 |
1983年 | 15篇 |
1982年 | 12篇 |
1981年 | 9篇 |
1979年 | 20篇 |
1978年 | 11篇 |
1976年 | 10篇 |
1974年 | 12篇 |
1973年 | 11篇 |
1971年 | 10篇 |
1970年 | 9篇 |
排序方式: 共有3441条查询结果,搜索用时 15 毫秒
1.
Behzad Emadi Mojtaba Ghahraman Rezaieh Mansour Sedighi 《Transfusion and apheresis science》2021,60(3):103132
Transfusion transmissible infections (TTIs) have been a public health challenge for the accessibility, quality and safety of blood transfusion. The present study aimed to consider the prevalence and the trends of hepatitis B virus (HBV), hepatitis C virus (HCV), Human T-cell leukemia virus type 1 (HTLV-1), human immunodeficiency virus (HIV) and syphilis across the ten years among retrospective blood donors. A retrospective investigation of blood donors’ data covering the period from 22 May 2009 to 22 May 2019 was done. Data was accumulated and analyzed from Blood Transfusion Center records, pertaining to all donors who were screened for various TTIs using respective immunological techniques. Out of the 682,171 screened donors in the 2009–2019 study period, 2470 (0.36 %) were infected with at least one infectious agent. The overall prevalence of HBV, HCV, HTLV-1, HIV and syphilis were 1700 (0.25 %), 184 (0.027 %), 335 (0.05 %), 4 (0.0.05 %) and 247 (0.036 %), respectively. The study showed male dominated donor pool (96.79 %) with higher prevalence (0.34 %) of TTIs compared to female donors (0.02 %) with 3.21 % population. Despite the low prevalence of TTIs in our study, HBV, HCV, syphilis and HIV have remained a big threat to safe blood transfusion in Iran. Strict adherence to selection criteria, algorithm of donor screening, use of highly sensitive and specific methods for detection of TTIs, regular consultation and health education programs, prevention and sanitization strategies to reduce the risk of TTIs are recommended to reduce the risk of TTIs and ensure the safety of blood transfusion for recipient. 相似文献
2.
Gokhlesh Kumar Subhodeep Sarker Simon Menanteau-Ledouble Mansour El-Matbouli 《Parasitology research》2015,114(6):2301-2308
3.
K. Dahan V. Audard F. Roudot-Thoraval D. Desvaux M. Abtahi H. Mansour M. Kumal P. Lang P. Grimbert 《American journal of transplantation》2006,6(7):1725-1730
The clinical outcome and appropriate management for patients showing 'borderline changes' on allograft biopsy after renal transplantation is still controversial. In an attempt to identify predictive factors of clinical outcome of patients with such lesions, we reviewed the clinical course of 91 patients with borderline changes. Multivariate analysis revealed significant and independent effects of histological stage (i + t < or = or > 2) and time to borderline changes (< or = or > 3 months after transplant) on serum creatinine levels at 1 year from borderline changes episodes (respectively, p = 0.04 and p = 0.02) and only a significant effect of time to borderline changes on serum creatinine levels at 2 years (p = 0.005). Renal function at 1 year and 2 years as 5- and 8-year graft survival were not significantly different in the group of patients treated with antirejection therapy (T group, n = 49) compared with the untreated group (UT group, n = 42). This study strongly suggests that borderline changes with histological score (i + t) > 2 and late episodes of borderline changes should be considered to be of poor prognosis. 相似文献
4.
5.
Antimurine antibody formation following OKT3 therapy 总被引:1,自引:0,他引:1
T J Schroeder M R First M E Mansour P E Hurtubise S Hariharan F C Ryckman R Munda D B Melvin I Penn W F Ballistreri 《Transplantation》1990,49(1):48-51
OKT3 is an IgG2a murine monoclonal antibody directed against the CD3 antigen receptor of human T lymphocytes. A major concern with OKT3 treatment in solid organ transplant recipients is the development of antimouse antibody, which may preclude retreatment with this agent. We have administered OKT3 on 215 occasions (150 renal, 34 hepatic, 26 cardiac, 5 pancreatic) in 179 patients between April 1982 and December 1988. The mean duration of treatment was 10.5 days (range, 2-22 days). Antimouse antibody data were analyzed on the most recent 133 treatment courses where the antibody status was available pretreatment. Determination of antimouse antibody production was elicited by ELISA technology at days 0, 7, 14, and 28 of OKT3 treatment. Patients were categorized according to the antibody response as follows: (a) absence of antibody; (b) low titer (1:100); or (c) high titer (greater than or equal to 1:1000). Our earlier experience has demonstrated that retreatment with OKT3 is successful in groups a and b. The development of antimurine antibodies was analyzed with regard to the following parameters: (1) The duration of OKT3 treatment; (2) treatment type (prophylactic, primary, or secondary); (3) primary treatment or retreatment; (4) concomitant immunosuppressive regimen (double or triple therapy); (5) dosage of concomitant immunosuppressive drugs; and (6) transplant organ type. The following results were obtained. (1) Duration of treatment had no effect on antibody production (11.0 days in antibody negative and 10.0 days in antibody positive). (2) There was no difference in antibody formation rates for the first treatment of OKT3 when it was used as prophylaxis (26%), primary (19%), or secondary (27%) therapy. (3) Antibody formation rate with first treatment was 29%; with retreatment, patients who were antibody negative following first treatment became positive in 28% of cases, and retreated patients who were low titer positive following first treatment converted to high titer in 57% of cases. (4) Antibody formation was higher in patients receiving double immunosuppressive therapy (36%) than in those receiving triple immunosuppressive therapy (21%) during OKT3 treatment. (5) Concomitant immunosuppression was lower in the antibody-positive group during OKT3 therapy: steroids, 61 mg/day vs. 52 mg/day; azathioprine, 89 mg/day vs. 66 mg/day; CsA, 317 mg/day vs. 186 mg/day. (6) Antibody formation rates were lower in non-renal transplants following first treatment with OKT3 (liver 17%, heart 17%, kidney 28%); this reflects the higher doses of concomitant immunosuppressive therapy used in nonrenal transplants.(ABSTRACT TRUNCATED AT 400 WORDS) 相似文献
6.
G V Stiegmann J S Goff A Mansour N Pearlman R M Reveille L Norton 《American journal of surgery》1992,163(2):227-230
Thirty-four patients with suspected common bile duct stones were randomized to undergo endoscopic cholangiography and stone removal prior to open cholecystectomy or to have open cholecystectomy, operative cholangiography, and common bile duct exploration. Sixteen underwent the first protocol, and 18 the second. Analysis of the ability to clear stones from the common bile duct, morbidity, mortality, hospital stay, length of operation, and hospital cost showed no difference in outcome between patients treated by either method. These data suggest there is neither an advantage nor a disadvantage to treating patients with suspected duct stones by precholecystectomy endoscopic cholangiography and stone removal. 相似文献
7.
Adel M. Mansour Robert W. Frenck Jr. Toni Darville Isabelle A. Nakhla Thomas F. Wierzba Yehia Sultan Magdy I. Bassiouny Kathryn McCarthy Richard F. Jacobs 《Clinical and Vaccine Immunology : CVI》2005,12(2):363-365
Cerebrospinal fluid gamma interferon (IFN-γ) and interleukin-10 levels in 39 patients with tuberculous meningitis were serially measured. Cytokine levels did not predict intracranial granuloma (IG) development, but IFN-γ levels in the top quartile after 1 month of therapy were highly associated (odds ratio = 18) with detection of an IG by computed tomography scanning. 相似文献
8.
Yang-Sheng Tzeng Eric Hoffman Janice Cook-Granroth Rie Maurer Niral Shah Joey Mansour Juerg Tschirren Mitchell Albert 《Magnetic resonance in medicine》2007,58(3):636-642
An anthropomorphic airway tree phantom was imaged with both hyperpolarized (HP) 3He MRI using a dynamic projection scan and computed tomography (CT). Airway diameter measurements from the HP 3He MR images obtained using a newly developed model-based algorithm were compared against their corresponding CT values quantified with a well-established method. Of the 45 airway segments that could be evaluated with CT, only 14 airway segments (31%) could be evaluated using HP 3He MRI. No airway segments smaller than approximately 4 mm in diameter and distal to the fourth generation were adequate for analysis in MRI. For the 14 airway segments measured, only two airway segments yielded a non-equivalent comparison between the two imaging modalities, while eight more had inconclusive comparison results, leaving only four airway segments (29%) that satisfied the designed equivalence criteria. Some of the potential problems in airway diameter quantification described in the formulation of the model-based algorithm were observed in this study. These results suggest that dynamic projection HP 3He MRI may have limited utility for measuring airway segment diameters, particularly those of the central airways. 相似文献
9.
Mansour Njah Radhia Hergli Jalel Gloulou Slim Ben Ahmed et Moncef Marzouki 《Sozial- und Pr?ventivmedizin》1994,39(5):280-286
Resumé Dans le but d'analyser les besoins d'une population en matière de dépistage des cancers, les attitudes, connaissances et comportements des femmes à propos des cancers du sein et du col utérin sont étudiées, auprès d'un groupe de consultantes tout venant de 3 centres de santé tunisiens (Kalaa-Kebira). Les résultats soulignent la nécessité d'informer la population concernant les facteurs de risque de ces maladies, particulièrement en ce qui concerne le cancer du sein, (1er cancer de la femme en Tunisie) mais surtout sur les signes d'appel et les moyens de dépistage disponibles. Le rôle des professionnels de la santé, plus du généraliste et de la sage-femme que du gynécologue apparait clair auprès des consultantes. L'éducation individuelle et de masse doit cependant aller de pair avec une sensibilisation et une formation des professionnels de la santé eux-mêmes en matière de dépistage.
Knowledges, attitudes and behaviors of Tunisian women about gynaecologic cancers
Summary With the aim to analyze population needs in the field of cancer screening (cervical and breast cancer), attitudes, behaviors and knowledge of a tunisien women group of health service user's were studied. Results clearly demonstrate the necessity to inform the concerned population about risk factors particularly concerning breast cancer (the most frequent cancer in Tunisia) but also early symptoms and available screening methods. This role is alloted to health professionals, more for general practitioners and midwives than for gynaecologists. Health education for women and groups, however, have to go hand in hand with training of health professionals in matter of test screening.
Kenntnisse, Haltung und Verhalten der tunesischen Frauen in Bezug auf gynäkologische Krebse
Zusammenfassung Haltung, Kenntnisse und Verhalten der Frauen gegenüber dem Brustkrebs und dem des Uterushalses wurden an Hand einer Patientinnengruppe in Tunesischen Gesundheitszentren (Kalaa-kebira) erlangt. Die Ergebnisse bestätigen die Notwendigkeit, die Bevölkerung über die Risikofaktoren dieser Krankheiten zu unterrichten, besonders was den Brustkrebs betrifft (den verbreitetsten Krebs bei Frauen in Tunesien), aber vor allem über die Krankheitsanzeichen und die verfügbaren diagnosemethoden. Die Rolle der Gesundheitskräfte, insbesondere die des Allgemeinarztes und der Hebamme, noch vor derjenigen des Frauenarztes, sind den Patientinnen verständlich. Die individuelle sowie die massenhafte Gesundheitserziehung muss Hand in Hand gehen mit einer Sensibilisierung und einer Ausbildung des Gesundheitspersonals in Sachen Diagnosemethoden.相似文献
10.