全文获取类型
收费全文 | 7661篇 |
免费 | 750篇 |
国内免费 | 39篇 |
专业分类
耳鼻咽喉 | 91篇 |
儿科学 | 266篇 |
妇产科学 | 129篇 |
基础医学 | 1025篇 |
口腔科学 | 211篇 |
临床医学 | 820篇 |
内科学 | 1741篇 |
皮肤病学 | 153篇 |
神经病学 | 707篇 |
特种医学 | 298篇 |
外国民族医学 | 2篇 |
外科学 | 1036篇 |
综合类 | 175篇 |
一般理论 | 1篇 |
预防医学 | 673篇 |
眼科学 | 133篇 |
药学 | 397篇 |
中国医学 | 14篇 |
肿瘤学 | 578篇 |
出版年
2023年 | 41篇 |
2022年 | 69篇 |
2021年 | 201篇 |
2020年 | 89篇 |
2019年 | 250篇 |
2018年 | 273篇 |
2017年 | 200篇 |
2016年 | 190篇 |
2015年 | 226篇 |
2014年 | 266篇 |
2013年 | 353篇 |
2012年 | 425篇 |
2011年 | 401篇 |
2010年 | 285篇 |
2009年 | 241篇 |
2008年 | 352篇 |
2007年 | 375篇 |
2006年 | 356篇 |
2005年 | 315篇 |
2004年 | 255篇 |
2003年 | 253篇 |
2002年 | 268篇 |
2001年 | 187篇 |
2000年 | 206篇 |
1999年 | 189篇 |
1998年 | 113篇 |
1997年 | 110篇 |
1996年 | 86篇 |
1995年 | 73篇 |
1994年 | 76篇 |
1993年 | 62篇 |
1992年 | 147篇 |
1991年 | 163篇 |
1990年 | 133篇 |
1989年 | 143篇 |
1988年 | 131篇 |
1987年 | 124篇 |
1986年 | 119篇 |
1985年 | 86篇 |
1984年 | 71篇 |
1983年 | 61篇 |
1982年 | 37篇 |
1981年 | 32篇 |
1980年 | 30篇 |
1979年 | 51篇 |
1978年 | 30篇 |
1977年 | 32篇 |
1976年 | 37篇 |
1975年 | 25篇 |
1973年 | 34篇 |
排序方式: 共有8450条查询结果,搜索用时 31 毫秒
1.
Ana Lopez Alonso 《Platelets》2015,26(4):317-323
AbstractWhile the interactions between Gram-positive bacteria and platelets have been well characterized, there is a paucity of data on the interaction between other pathogens and platelets. However, thrombocytopenia is a common feature with many infections especially viral hemorrhagic fever. The little available data on these interactions indicate a similarity with bacteria-platelet interactions with receptors such as FcγRIIa and Toll-Like Receptors (TLR) playing key roles with many pathogens. This review summarizes the known interactions between platelets and pathogens such as viruses, fungi and parasites. 相似文献
2.
Maria Gonzalez-Cao Cristina Carrera Juan Francisco Rodriguez Moreno Pedro Rodríguez-Jiménez Mónica Antoñanzas Basa Rosa Feltes Ochoa Teresa Puertolas Eva Muñoz-Couselo José Luis Manzano Ivan Marquez-Rodas Juan Martín-Liberal Ainara Soria Pilar Lopez Criado Almudena Garcia-Castaño Aram Boada Pablo Ayala de Miguel Susana Puig Guillermo Crespo Alfonso Berrocal 《Journal of the American Academy of Dermatology》2021,84(5):1412-1415
3.
4.
Luis Veloza Cristina Teixido Natalia Castrejon Fina Climent Ana Carri Marta Marginet Davide Soldini Blanca Gonzlez‐Farr Inmaculada Ribera‐Cortada Armando Lopez‐Guillermo Eva Gonzlez‐Barca Adriana Sierra Mileyka Herrera Cndida Gmez Adriana Garcia Olga Balagu Elias Campo Antonio Martinez 《Histopathology》2019,75(6):799-812
5.
Pedro Lopez Matheus Daros Pinto Ronei Silveira Pinto 《Ultrasound in medicine & biology》2019,45(2):612-616
In the work described here, our aim was to determine, in an elderly population, changes in muscle thickness (MT), cross-sectional area (CSA) and echo intensity (EI) of the quadriceps muscles at four time points (0, 5, 10 and 15 min; i.e., T0, T5, T10 and T15, respectively) after changing from a standing to supine position. Twenty-one elderly participants (14 men: 68.1 ± 4.6 y; 8 women: 66.8 ± 4.1 y) were evaluated at four time points. Rectus femoris CSA (RFCSA), MT and EI of the quadriceps femoris (QF) muscles were assessed. EI significantly increased from T0 to T5, T10 and T15 (p < 0.001), whereas no differences were observed between T5 and T15 in the rectus femoris (RFEI), vastus intermedius (VIEI) and quadriceps femoris (QFEI). No differences were observed between any time points in the RFCSA and MT of QF muscles. In summary, these results suggest that periods >5 min are not necessary to obtain consistent MT and EI measurements of quadriceps femoris muscles in the elderly population. 相似文献
6.
7.
Michelle Cleary Garry Walter Jan Sayers Violeta Lopez Catherine Hungerford 《Issues in mental health nursing》2015,36(4):266-271
Cultures of performativity may contribute to organizational and individual arrogance. Workplace organizations have individuals who at various times will display arrogance, which may manifest in behaviours, such as an exaggerated sense of self-importance, dismissiveness of others, condescending behaviors and an impatient manner. Arrogance is not a flattering label and irrespective of the reason or the position of power, in the context of organizational behaviors, may not be useful and may even be detrimental to the work environment. Thus, it is timely to reflect on the implications of arrogance in the workplace. Advocacy and empowerment can be undermined and relationships adversely impacted, including the achievement of positive consumer outcomes. This paper provides an introduction to arrogance, and then discusses arrogance to promote awareness of the potential consequences of arrogance and its constituent behaviors. 相似文献
8.
Patricia A Wilkosz Sachiko Miyahara Oscar L Lopez Steven T Dekosky Robert A Sweet 《The American journal of geriatric psychiatry》2006,14(4):352-360
BACKGROUND: Psychotic symptoms in Alzheimer disease (AD+P) identify a heritable phenotype associated with more rapid cognitive decline. The authors have proposed that AD+P is itself a composite of a misidentification and a paranoid subtype with increased cognitive impairment restricted to the misidentification type. Most prior studies of the clinical correlates of AD+P have been limited, however, by the inclusion of prevalent cases. METHODS: Subjects with possible or probable AD or mild cognitive impairment (MCI) without psychosis at study entry were assessed at the time of initial presentation and then annually. Psychotic symptoms were assessed using the CERAD Behavioral Rating Scale. Survival analyses used Cox proportional hazard models with time-dependent covariates to examine the predictors of psychosis onset. RESULTS: A total of 288 subjects completed at least one follow-up examination. Mean duration of follow-up was 22.1 months. The incidence of psychosis was 0.19 per person-year. Cognitive impairment was associated with onset of psychosis, largely as a result of its association with onset of the misidentification, but not the paranoid, subtype. Including psychotropic medication use in the model revealed an association of antidepressant use with the onset of psychosis. This latter association appeared to arise from an underlying association between depression and the risk of psychosis onset rather than from antidepressant treatment. CONCLUSION: These findings are consistent with the hypothesis that the misidentification and the paranoid subtypes each define a more biologically homogeneous group than AD+P as a whole. Further exploration of the relationship between depressive symptoms and psychosis in patients with AD is warranted. 相似文献
9.
10.
Akira Sawaki Nobumasa Mizuno Kuniyuki Takahashi Tsuneya Nakamura Masahiro Tajika Hiroki Kawai Toshifumi Isaka Hiroshi Imaoka Yasuyuki Okamoto Masatoshi Aoki Hiroyuki Inoue Ahmed AS Salem Yasushi Yatabe Kenji Yamao 《Digestive endoscopy》2006,18(1):40-44
Background: Gastrointestinal stromal tumors (GIST) are one of the most common mesenchymal tumors of the gastrointestinal tract. GIST are defined by positive immunohistochemical staining for KIT or CD34 and thus are generally diagnosed after surgery. Because small GIST are rarely diagnosed before surgery, the clinical course of these small tumors is not clear. The aim of the present study was to follow changes in size and configuration of small GIST that were pathologically confirmed using endoscopic ultrasonography‐guided fine‐needle aspiration biopsy (EUS‐FNAB). Methods: Between July 1997 and December 2003, 16 tumors in 16 patients (10 men and 6 women) with an immunohistochemical diagnosis of GIST were regularly followed in our hospital. The median patient age when EUS‐FNAB was performed was 62 years (range 26–82 years) and the median follow‐up period was 4.9 years (range 0.5–9.6 years). Results: Fourteen tumors showed no remarkable changes in size and shape during follow up compared with the initial diagnosis. Two tumors enlarged: one tumor approximately doubled its diameter in 8 years and the other tumor increased from 1.8 cm at diagnosis to up to 10 cm after only 2 years. Doubling time of the latter tumor was calculated as 3.1 months. Conclusions: We conclude that EUS‐FNAB might be a good modality for final diagnosis of GIST without surgery, and that GIST without rapid growth on follow up can be endoscopically followed. 相似文献