全文获取类型
收费全文 | 1409篇 |
免费 | 127篇 |
国内免费 | 19篇 |
专业分类
耳鼻咽喉 | 9篇 |
儿科学 | 83篇 |
妇产科学 | 9篇 |
基础医学 | 194篇 |
口腔科学 | 65篇 |
临床医学 | 196篇 |
内科学 | 222篇 |
皮肤病学 | 46篇 |
神经病学 | 102篇 |
特种医学 | 254篇 |
外科学 | 128篇 |
综合类 | 39篇 |
预防医学 | 64篇 |
眼科学 | 13篇 |
药学 | 49篇 |
1篇 | |
肿瘤学 | 81篇 |
出版年
2022年 | 4篇 |
2021年 | 11篇 |
2020年 | 11篇 |
2019年 | 10篇 |
2018年 | 16篇 |
2017年 | 10篇 |
2016年 | 15篇 |
2015年 | 31篇 |
2014年 | 25篇 |
2013年 | 46篇 |
2012年 | 33篇 |
2011年 | 35篇 |
2010年 | 63篇 |
2009年 | 57篇 |
2008年 | 32篇 |
2007年 | 45篇 |
2006年 | 40篇 |
2005年 | 38篇 |
2004年 | 33篇 |
2003年 | 41篇 |
2002年 | 29篇 |
2001年 | 34篇 |
2000年 | 23篇 |
1999年 | 43篇 |
1998年 | 89篇 |
1997年 | 82篇 |
1996年 | 65篇 |
1995年 | 56篇 |
1994年 | 39篇 |
1993年 | 55篇 |
1992年 | 22篇 |
1991年 | 35篇 |
1990年 | 25篇 |
1989年 | 54篇 |
1988年 | 42篇 |
1987年 | 34篇 |
1986年 | 24篇 |
1985年 | 22篇 |
1984年 | 13篇 |
1983年 | 20篇 |
1982年 | 20篇 |
1981年 | 19篇 |
1980年 | 16篇 |
1979年 | 4篇 |
1978年 | 17篇 |
1977年 | 14篇 |
1976年 | 15篇 |
1975年 | 12篇 |
1974年 | 9篇 |
1875年 | 6篇 |
排序方式: 共有1555条查询结果,搜索用时 15 毫秒
1.
2.
3.
Pyomyositis: characteristics at CT and MR imaging 总被引:9,自引:0,他引:9
4.
AJ Larner MRCP 《International journal of clinical practice》1994,48(5):272-274
SUMMARY A case is reported of pseudohyperphosphataemia in association with a monoclonal gammopathy of undetermined significance. 相似文献
5.
6.
D De AJ Kanwar S Handa 《Journal of the European Academy of Dermatology and Venereology》2006,20(7):853-859
BACKGROUND: Diagnosis of atopic dermatitis (AD) depends on clinical features because no definitive diagnostic test exists. Criteria proposed by Hanifin and Rajka (Acta Derm Venereol (Stockh) 1980; Suppl 92: 44-47) were acceptable for hospital-based studies but were found not to be suitable for field studies. A UK working party formulated clinical diagnostic criteria that could be used in both hospital and epidemiological settings. Validation studies of the criteria showed widely variable results, probably due to different clinical settings and ethnicity. AIM AND OBJECTIVE: This study was undertaken to validate Hanifin and Rajka's criteria and to assess the comparative efficacy of their criteria and the UK working party's diagnostic criteria in the diagnosis of AD in a hospital setting in North India. SUBJECTS AND METHODS: This study serially included 101 patients with AD and 48 controls of paediatric age group. The study period was from July 2003 to December 2004. RESULTS: Hanifin and Rajka's criteria (sensitivity 96%, specificity 93.75%, positive predictive value 97% (PPV) and negative predictive value (NPV) 91.84%) had a statistical advantage over the UK working party's diagnostic criteria (sensitivity 86%, specificity 95.83%, PPV 97.75% and NPV 76.67%), with a P-value < 0.005. 相似文献
7.
SUMMARY Impotence is a common symptom which can cause considerable distress to both the sufferer and his partner. The use of pharmacotherapy to improve erectile function will continue to increase as safe and effective drugs are developed. However, restoring erectile function should not be the only treatment objective. It is also essential to address personal and emotional factors in the sufferer, conflicts in his relationship with his partner, and sexual problems in his partner, all of which may be instrumental in causing or maintaining the presenting impotence. We advocate a combined approach with appropriate medical treatment and sex and couple therapy 相似文献
8.
Acute appendicitis: CT and US correlation in 100 patients 总被引:19,自引:1,他引:18
9.
The role of somatomedin/insulin-like growth factors (Sm/IGFs) in neural growth and development is not clearly defined. To characterize Sm/IGF receptors and to correlate binding with the biologic actions of Sm/IGFs in a homogeneous population of neural cells, we isolated and studied a nearly pure population of cultured astroglial monolayers derived from cerebral cortices of neonatal rats. Binding of radiolabeled Sm/IGFs was specific, saturable, and reversible, with 90% of the binding occurring within 6 hr of incubation at 4 degrees C. Competitive binding studies with Sm-C/IGF I yielded curvilinear Scatchard plots, while studies with IGF II and multiplication stimulating activity (MSA) yielded linear plots, suggesting that 125I-Sm-C/IGF I binds to more than 1 receptor species, and 125I-IGF II and 125I-MSA bind to one only. These findings were supported by affinity-labeling studies with radiolabeled Sm/IGFs using disuccinimidyl suberate as a cross-linking agent. Sm-C/IGF I appeared to bind to both type I and II Sm/IGF receptors, because cross-linked 125I-Sm-C/IGF I-receptor complexes with molecular weight (Mr) of greater than 300,000 (300K) and 130K (type I receptor) were observed under nonreducing and reducing conditions, respectively, as were 220 and 260K complexes (type II receptor) under the same respective conditions. 125I-IGF II and 125I-MSA, however, bound only to the Mr 220 and 260K moieties under nonreducing and reducing conditions, respectively, suggesting that these peptides bind only to the type II receptor. Competitive binding studies of the cross-linked moieties were consistent with this interpretation. In contrast, 125I-insulin bound poorly to astroglia (less than 0.5% specific binding), and cross-linking studies could not definitely distinguish among low-affinity binding to the type I Sm/IGF receptor, binding to a paucity of insulin receptors, or both. In addition, by combining autoradiography to localize 125I-Sm/IGFs binding on astroglial cells and immunocytochemistry with anti-glial fibrillary acidic protein to identify the cell type, we have demonstrated cell-surface binding and apparent internalization of radiolabeled Sm/IGFs. Concurrent studies of Sm/IGF stimulation of 3H-thymidine incorporation revealed that these cells were most sensitive to Sm-C/IGF I, followed by IGF II and MSA, and insulin. MSA and IGF II, however, were the most potent followed by Sm-C/IGF I and then insulin. Half-maximal stimulations of 3H-thymidine incorporation corresponded closely with half-maximal binding displacement for Sm-C/IGF I and less so for IGF II and MSA.(ABSTRACT TRUNCATED AT 400 WORDS) 相似文献
10.
Perforated colorectal neoplasms: correlation of clinical, contrast enema, and CT examinations 总被引:2,自引:0,他引:2
Hulnick DH; Megibow AJ; Balthazar EJ; Gordon RB; Surapenini R; Bosniak MA 《Radiology》1987,164(3):611-615
Results of clinical, contrast enema (CE), and computed tomographic (CT) examinations in 39 patients with perforated colorectal neoplasms were retrospectively reviewed. Twenty patients were toxemic at initial presentation, but in only four patients was the diagnosis of perforated colorectal neoplasm initially suspected clinically. CE study was performed in 22 patients and enabled the diagnosis of perforated neoplasm in 11 cases, neoplasm alone in eight, and neither neoplasm nor perforation in three. CT was performed in 38 patients and enabled the diagnosis of perforated neoplasm in 36; pericolic phlegmon but no mass lesion was evident in two. In 16 patients, CT also demonstrated metastatic disease. Because of its reliability in establishing the diagnosis and staging the extent of the inflammatory and neoplastic disease, CT is indicated in cases of suspected or proved perforated colorectal neoplasm and in cases in which CE study findings are indeterminate or suggestive of perforated neoplasm. 相似文献