全文获取类型
收费全文 | 24429篇 |
免费 | 2141篇 |
国内免费 | 696篇 |
专业分类
耳鼻咽喉 | 279篇 |
儿科学 | 434篇 |
妇产科学 | 590篇 |
基础医学 | 3026篇 |
口腔科学 | 491篇 |
临床医学 | 2760篇 |
内科学 | 4995篇 |
皮肤病学 | 304篇 |
神经病学 | 1473篇 |
特种医学 | 674篇 |
外国民族医学 | 5篇 |
外科学 | 3777篇 |
综合类 | 1783篇 |
现状与发展 | 3篇 |
一般理论 | 7篇 |
预防医学 | 1336篇 |
眼科学 | 838篇 |
药学 | 1966篇 |
6篇 | |
中国医学 | 639篇 |
肿瘤学 | 1880篇 |
出版年
2024年 | 46篇 |
2023年 | 286篇 |
2022年 | 528篇 |
2021年 | 837篇 |
2020年 | 621篇 |
2019年 | 617篇 |
2018年 | 733篇 |
2017年 | 682篇 |
2016年 | 636篇 |
2015年 | 866篇 |
2014年 | 1117篇 |
2013年 | 1257篇 |
2012年 | 1758篇 |
2011年 | 1818篇 |
2010年 | 1161篇 |
2009年 | 969篇 |
2008年 | 1355篇 |
2007年 | 1378篇 |
2006年 | 1435篇 |
2005年 | 1355篇 |
2004年 | 1100篇 |
2003年 | 971篇 |
2002年 | 945篇 |
2001年 | 672篇 |
2000年 | 647篇 |
1999年 | 578篇 |
1998年 | 231篇 |
1997年 | 239篇 |
1996年 | 197篇 |
1995年 | 150篇 |
1994年 | 135篇 |
1993年 | 96篇 |
1992年 | 247篇 |
1991年 | 211篇 |
1990年 | 192篇 |
1989年 | 160篇 |
1988年 | 140篇 |
1987年 | 136篇 |
1986年 | 110篇 |
1985年 | 82篇 |
1984年 | 65篇 |
1983年 | 41篇 |
1982年 | 60篇 |
1981年 | 48篇 |
1980年 | 44篇 |
1979年 | 44篇 |
1978年 | 41篇 |
1975年 | 24篇 |
1973年 | 22篇 |
1971年 | 22篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
Haya Mohammed BSc MChB M. Yousuf Salmasi MRCS Massimo Caputo PhD Gianni D. Angelini PhD Hunaid A. Vohra PhD 《Journal of cardiac surgery》2020,35(6):1209-1219
Background
Limited data exists demonstrating the efficacy of minimally invasive surgery (MIS) compared to median sternotomy (MS) for multiple valvular disease (MVD). This systematic review and meta-analysis aims to compare operative and peri-operative outcomes of MIS vs MS in MVD.Methods
PubMed, Ovid, and Embase were searched from inception until August 2019 for randomized and observational studies comparing MIS and MS in patients with MVD. Clinical outcomes of intra- and postoperative times, reoperation for bleeding and surgical site infection were evaluated.Results
Five observational studies comparing 340 MIS vs 414 MS patients were eligible for qualitative and quantitative review. The quality of evidence assessed using the Newcastle-Ottawa scale was good for all included studies. Meta-analysis demonstrated increased cardiopulmonary bypass time for MIS patients (weighted mean difference [WMD], 0.487; 95% confidence interval [CI], 0.365-0.608; P < .0001). Similarly, aortic cross-clamp time was longer in patients undergoing MIS (WMD, 0.632; 95% CI, 0.509-0.755; P < .0001). No differences were found in operative mortality, reoperation for bleeding, surgical site infection, or hospital stay.Conclusions
MIS for MVD have similar short-term outcomes compared to MS. This adds value to the use of minimally invasive methods for multivalvular surgery, despite conferring longer operative times. However, the paucity in literature and learning curve associated with MIS warrants further evidence, ideally randomized control trials, to support these findings.2.
3.
The molecular and clinical impact of hepatocyte growth factor, its receptor, activators, and inhibitors in wound healing 总被引:1,自引:0,他引:1
Kevin Conway MRCS ; Patricia Price PhD ; Keith G. Harding FRCS ; Wen G. Jiang MD 《Wound repair and regeneration》2006,14(1):2-10
Wound healing involves a number of cellular and molecular events, many of which are controlled by soluble growth factors. In the process of healing, hepatocyte growth factor, a cytokine known to act as mitogen, motogen, and morphogen, has been postulated to play multiple roles during several stages of this complex biological process. Produced primarily by stromal fibroblasts, hepatocyte growth factor regulates angiogenesis, vascular permeability, cell migration, matrix deposition and degradation, and other biological processes. The current article discusses recent progress in understanding the multiple roles played by this growth factor in tissue repair. 相似文献
4.
Caroline A. Harrison BMedSci MRCS ; Martin J. Heaton MD FRCS ; Christopher M. Layton PhD ; Sheila Mac Neil PhD 《Wound repair and regeneration》2006,14(2):203-209
To produce a stable epidermis, keratinocytes need to be firmly attached to the basement membrane. However, following wounding, keratinocytes are required to develop a migratory phenotype in order to reepithelialize the wound. To investigate some of the issues underlying reepithelialization, we have developed a three-dimensional in vitro model of tissue-engineered skin, comprising sterilized human dermis seeded with human keratinocytes and dermal fibroblasts. Using this model, we have shown that the inclusion of fibroblasts within the model increases the stability of keratinocyte attachment. We have also demonstrated that keratinocyte migration occurs most effectively in the absence of a basement membrane and following the inclusion of fibroblasts in the model. In addition, subjecting the keratinocyte layer to mechanical trauma induces a migratory phenotype. We conclude that this three-dimensional in vitro wound model can be used to increase our understanding of the factors that enhance keratinocyte migration and hence wound healing in vivo. 相似文献
5.
赖雷成 《福建中医学院学报》1992,(2)
“搓滚舒筋”练功疗法,是一种以竹筒为简易器械的脚底搓滚练功治疗“筋挛缩”症的方法。最早文献见于马王堆汉墓出土的帛书《五十二病方》,起码有两干多年的渊源。骨伤科常用之,内、外诸科亦有用之。这一传统疗法,筒、便、廉、验,值得弘扬。 相似文献
6.
7.
8.
9.
10.
Osteochondral Fracture of the Fourth Metatarsal Head Treated by Open Reduction and Internal Fixation
Praveen K.R. Mereddy MBBS MSOrth DNB Orth MRCSEd Andrew Molloy MBchB MRCS FRCS Michael S. Hennessy BSc MBchB FRCSEd 《The Journal of foot and ankle surgery》2007,46(4):320-322
Fracture of the metatarsal head is uncommon, and reports of isolated osteochondral fracture of the metatarsal head are rare. Because of the distal location of the fracture, it is difficult to achieve and maintain reduction, and potential complications include avascular necrosis and subchondral fatigue fracture. The authors present a case of an osteochondral fracture in a 40-year-old man, which was treated by open reduction and internal fixation with a single twist-off screw, with good results 12 months postoperatively. 相似文献