全文获取类型
收费全文 | 2469篇 |
免费 | 289篇 |
国内免费 | 14篇 |
专业分类
耳鼻咽喉 | 27篇 |
儿科学 | 155篇 |
妇产科学 | 58篇 |
基础医学 | 356篇 |
口腔科学 | 48篇 |
临床医学 | 436篇 |
内科学 | 543篇 |
皮肤病学 | 24篇 |
神经病学 | 126篇 |
特种医学 | 201篇 |
外科学 | 290篇 |
综合类 | 74篇 |
一般理论 | 1篇 |
预防医学 | 187篇 |
眼科学 | 38篇 |
药学 | 79篇 |
中国医学 | 5篇 |
肿瘤学 | 124篇 |
出版年
2023年 | 20篇 |
2022年 | 14篇 |
2021年 | 31篇 |
2020年 | 40篇 |
2019年 | 42篇 |
2018年 | 70篇 |
2017年 | 71篇 |
2016年 | 76篇 |
2015年 | 66篇 |
2014年 | 83篇 |
2013年 | 124篇 |
2012年 | 92篇 |
2011年 | 98篇 |
2010年 | 90篇 |
2009年 | 93篇 |
2008年 | 98篇 |
2007年 | 94篇 |
2006年 | 109篇 |
2005年 | 83篇 |
2004年 | 78篇 |
2003年 | 81篇 |
2002年 | 57篇 |
2001年 | 95篇 |
2000年 | 76篇 |
1999年 | 60篇 |
1998年 | 85篇 |
1997年 | 76篇 |
1996年 | 72篇 |
1995年 | 73篇 |
1994年 | 38篇 |
1993年 | 54篇 |
1992年 | 53篇 |
1991年 | 44篇 |
1990年 | 42篇 |
1989年 | 34篇 |
1988年 | 39篇 |
1987年 | 35篇 |
1986年 | 34篇 |
1985年 | 22篇 |
1984年 | 28篇 |
1983年 | 29篇 |
1982年 | 16篇 |
1981年 | 21篇 |
1980年 | 16篇 |
1979年 | 19篇 |
1978年 | 12篇 |
1977年 | 22篇 |
1976年 | 13篇 |
1975年 | 8篇 |
1973年 | 8篇 |
排序方式: 共有2772条查询结果,搜索用时 16 毫秒
1.
Gina Kearney MSN RN CS AHN-BC JeMe Cioppa-Mosca PT MBA Margaret G. E. Peterson Ph.D C. Ronald MacKenzie MD 《HSS journal》2007,3(2):198-201
In an outpatient rehabilitation setting, both patients’ use and therapists’ knowledge of complementary and alternative medicine
(CAM) varies widely. Based on this observation and a recognition of CAM as an emerging practice area for rehabilitation professionals,
it was felt that a thorough and consistent approach to the education and orientation of physical therapists to the world of
CAM and integrative care was needed. This special interest paper will describe one center’s approach, development, and use
of a unique and comprehensive training manual designed to provide both a structured and standardized approach for educating
physical therapists about CAM and related therapeutic modalities. This innovative teaching tool allows for multiple methods
of content delivery within a multidisciplinary format and can be used for those who practice currently or desire to practice
in an integrative care environment. 相似文献
2.
Benign intracranial hypertension and recombinant growth hormone therapy in Australia and New Zealand
PA Crock JD McKenzie AM Nicoll NJ Howard W Cutfield LK Shield G Byrne 《Acta paediatrica (Oslo, Norway : 1992)》1998,87(4):381-386
Benign intracranial hypertension (BIH) is reported in three children from Australia and one from New Zealand, who were being treated with recombinant human growth hormone (rhGH). Three males and one female, aged between 10.5 and 14.2 y, developed intracranial hypertension within 2 weeks to 3 months of starting treatment. A national database, OZGROW, has been prospectively collecting data on all 3332 children treated with rhGH in Australia and New Zealand from January 1986 to 1996. The incidence of BIH in children treated with growth hormone (GH) is small, 1.2 per 1000 cases overall, but appears to be greater with biochemical GHD (<10IUml -1 ), i.e. 6.5/1000 (3 in 465 cases), relative risk 18.4, 95% confidence interval 1.9-176.1, than in all other children on the database. The incidence in patients with Turner's syndrome was 2.3/1000 (1 in 428 cases). No cases in patients with partial GHD (10–20 IUml -1 ) or chronic renal failure were identified. Possible causative mechanisms are discussed. The authors'practice is now to start GH replacement at less than the usual recommended dose of 14IUm-2 week-1 in those children considered to be at high risk of developing BIH. Ophthalmological evaluation is recommended for children before and during the first few months following commencement of rhGH therapy and is mandatory in the event of peripheral or facial oedema, persistent headaches, vomiting or visual symptoms. The absence of papilledema does not exclude the diagnosis. 相似文献
3.
In a prospective, randomized, double-blind study, 49 patients underwent lumbar myelography using iotrol (24 patients) or metrizamide (25 patients). The diagnostic imaging adequacy of iotrol was comparable with that of metrizamide. After iotrol myelography, adverse reactions were fewer, less severe, and of shorter duration than were those following metrizamide myelography. Thirteen of 24 patients (54%) receiving iotrol reported some adverse reactions compared with 24 of 25 patients (96%) receiving metrizamide. Five moderate and one severe adverse reaction occurred in the group receiving iotrol. Fourteen moderate and eight severe adverse reactions occurred in the group receiving metrizamide. Thirty-eight patients underwent electroencephalography both before and after myelography (19 iotrol and 19 metrizamide). None of the EEGs obtained after iotrol myelography changed from baseline, while seven of the EEGs obtained after metrizamide myelography showed changes from baseline. Iotrol was judged superior to metrizamide as a contrast medium in this patient population. 相似文献
4.
One of the few disinfectants known to inactivate the causative agent of Creutzfeldt-Jakob Disease is NaOH. In this study, NaOH was evaluated as a possible routine treatment for human dura mater alloimplants. Use of high concentration NaOH (1 M) resulted in protein loss and macroscopic changes to the tissue. Lower concentrations (0.1 M), although exhibiting little direct detrimental effect, greatly increased the susceptibility of the tissue to collagenase digestion. The use of NaOH treated commercial or institutionally prepared human dura mater should be approached with caution. 相似文献
5.
Source agreement in assessing youth stress and negative affectivity: New evidence for an old problem
The present study examined dichotomies potentially relevant to parentchild and interparent agreement in the assessment of internalizing problems in youngsters. Specifically, 98 children and their parents completed the Daily Life Stressors Scale or a variant to examine child ratings of daily stress, parent ratings of their children's daily stress, and parent predictions of how their children would self-rate their stress. In addition, a distinction was made between subscores of negative affectivity and stressful life events. Results indicated moderate parent-child and interparent agreement, with the latter somewhat more influenced by a negative affectivity-stressful events dichotomy. Parent-child agreement appeared more enhanced for items involving more parental contact. Implications of these data for future research are discussed. 相似文献
6.
IgM allotype heterozygous F1 mice were independently suppressed for Igh6a or Igh6b to
evaluate the contribution of B-1 and B-2 cells to natural serum IgM levels and Ab responses.
B-2 B cells expressing IgM of the suppressed allotype were evident in the spleens of
suppressed mice 4 to 6 weeks after cessation of the suppression regimen, whereas B-1 B
cells of the suppressed allotype were undetectable for up to 9 months. Although serum IgM
of the suppressed allotype was initially depleted in mice suppressed for either allotype, by
7 months of age, there were detectable levels of IgM of the suppressed allotype in the
serum; however, the levels were significantly below that found in nonsuppressed mice.
When mice were immunized with either the T-independent or T-dependent form of
phosphorylcholine, those suppressed for either allotype, and consequently depleted of B-1
B cells of that allotype, did not respond with phosphorylcholine-specific IgM of the
suppressed allotype. In contrast, when mice were immunized with α1-3 dextran, the Igh6a
allotype-suppressed mice were able to produce dextran-specific IgM of that allotype. These
results show that allotype-bearing B-1 cells of both allotypes can be effectively suppressed
by this suppression protocol and this produces long-lasting effects on B-1 cell levels and
serum IgM of the suppressed allotype. These observations reflect the derivation of the
majority of B-1 cells from fetal-neonatal precursors, which cannot be replaced by newly
emerging B-2 cells of adult origin. Their ablation by antibody treatment results in
permanent alterations to the adult B-cell repertoire. 相似文献
7.
8.
S F Johnson S B Johnson W E Strodel D E Barker P A Kearney 《The Journal of trauma》1991,31(11):1546-1550
Proximal upper extremity (subclavian and axillary) vascular injury (SAVI) and brachial plexus injury (BPI) occur uncommonly. However, BPI may be associated with SAVI and frequently is an important determinant of long-term disability. The medical records of patients with traumatic SAVI, BPI, or both over a 5-year period were reviewed. A total of 31 patients were identified. The group was predominantly male (28 men/3 women) with a mean age of 30.5 +/- 1.8 years (range, 15-63 years). Blunt trauma accounted for 43.5% of SAVI cases and 77.8% of BPI cases. Thirteen patients (41.9%) sustained SAVI alone (group I), 10 patients (32.2%) had combined SAVI and BPI (group II), and 8 patients (25.9%) had BPI alone (group III). Subclavian and axilliary vascular injury occurred in 10 of 18 patients (55.6%) with a BPI. Brachial plexus injury occurred in 10 of 23 patients (43.5%) with a SAVI. Patients with SAVI from blunt trauma were significantly more likely to have an associated complete BPI than patients with penetrating trauma. All patients with a complete BPI (6 patients) had an associated SAVI regardless of mechanism of injury. Only one patient with a partial BPI from blunt trauma had an associated SAVI. The Injury Severity Score was significantly higher for patients in group II. An average of 2.8 and 3.3 associated injuries were observed in patients with SAVI (groups I and II) versus patients without SAVI (group III), respectively. No patient who had a complete BPI showed an improvement in neurologic status during a mean follow-up of 7.2 months. No late vascular sequelae occurred in group-III patients.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
9.
10.
臂丛神经根性损伤膈神经移位术对青壮年患者早期呼吸功能的影响 总被引:1,自引:1,他引:0
目的研究臂丛神经损伤膈神经移位术对青壮年患者早期呼吸功能的影响.方法对16例接受膈神经移位治疗的患者,在术前、术后(10 d)进行肺功能指标的比较,同时定期进行门诊随访,观察呼吸系统自觉症状程度.结果13例术后出现了不同程度的供氧不足症状,16例全部出现一侧膈肌抬高,术后第10天肺活量(VC)、肺活量预计值百分数(VC%)分别比术前减少37.98%和26.88%,两者差异有统计学意义(tvc=11.532、tvc%=0,P<0.01).其它项目如残气量(RV)较术前轻度下降,肺总量(TLC)下降值达到术前肺总量的36.49%,残气量/肺总量比值(RV/TLC%)较术前上升了4.75%,上述各指标的差值均有统计学意义.1 s用力呼气量/用力肺活量比值(FEV1/FVC)和术前比基本无改变,但其差值有统计学意义.膈神经移位右侧(10例)与左侧(6例)术前、术后肺活量比较差异有统计学意义.术后随访8个月~2年,所有患者均无明显呼吸困难和胸闷等症状.结论膈神经移位术后对青壮年患者肺容量有较大的丧失,肺通气功能减弱和小气道阻力增加,但其丧失程度在机体自身代偿耐受范围内,不会导致急剧发生的严重呼吸功能障碍.建议对右侧臂丛神经根性损伤的患者,术前进行严格的肺、心功能检查,避免发生较为严重的并发症. 相似文献