全文获取类型
收费全文 | 6554篇 |
免费 | 444篇 |
国内免费 | 128篇 |
专业分类
耳鼻咽喉 | 58篇 |
儿科学 | 184篇 |
妇产科学 | 204篇 |
基础医学 | 797篇 |
口腔科学 | 179篇 |
临床医学 | 797篇 |
内科学 | 1584篇 |
皮肤病学 | 116篇 |
神经病学 | 354篇 |
特种医学 | 642篇 |
外科学 | 747篇 |
综合类 | 156篇 |
预防医学 | 217篇 |
眼科学 | 161篇 |
药学 | 436篇 |
中国医学 | 37篇 |
肿瘤学 | 457篇 |
出版年
2023年 | 22篇 |
2022年 | 68篇 |
2021年 | 118篇 |
2020年 | 73篇 |
2019年 | 100篇 |
2018年 | 149篇 |
2017年 | 112篇 |
2016年 | 133篇 |
2015年 | 253篇 |
2014年 | 215篇 |
2013年 | 255篇 |
2012年 | 389篇 |
2011年 | 378篇 |
2010年 | 275篇 |
2009年 | 204篇 |
2008年 | 297篇 |
2007年 | 339篇 |
2006年 | 282篇 |
2005年 | 270篇 |
2004年 | 244篇 |
2003年 | 304篇 |
2002年 | 273篇 |
2001年 | 208篇 |
2000年 | 186篇 |
1999年 | 150篇 |
1998年 | 149篇 |
1997年 | 126篇 |
1996年 | 148篇 |
1995年 | 113篇 |
1994年 | 113篇 |
1993年 | 108篇 |
1992年 | 114篇 |
1991年 | 100篇 |
1990年 | 90篇 |
1989年 | 89篇 |
1988年 | 91篇 |
1987年 | 85篇 |
1986年 | 82篇 |
1985年 | 60篇 |
1984年 | 32篇 |
1983年 | 40篇 |
1982年 | 35篇 |
1981年 | 35篇 |
1980年 | 26篇 |
1979年 | 29篇 |
1978年 | 23篇 |
1977年 | 29篇 |
1976年 | 19篇 |
1975年 | 14篇 |
1972年 | 10篇 |
排序方式: 共有7126条查询结果,搜索用时 15 毫秒
1.
2.
3.
Micro‐evolution of the hepatitis B virus genome in hepatitis B e‐antigen‐positive carriers: Comparison of genotypes B and C at various immune stages
下载免费PDF全文
![点击此处可从《Journal of gastroenterology and hepatology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
4.
5.
6.
7.
Objective This study evaluated the Impact on Sibling scale, a six-item measure of parents' perception of the effects of a child's illness on healthy siblings.
Methods Participants were 122 parents of a child with chronic illness, developmental disability, or autism spectrum disorder, and a well sibling aged 4–13 years. Parents completed the Impact on Sibling scale and the Child Behavior Checklist about the sibling, and completed the revised Impact on Family scale and the Brief Symptom Inventory about themselves.
Results The Impact on Sibling score was correlated with measures of sibling, parent and family functioning. The internal consistency of the Impact on Sibling scale was higher for families with children with chronic illness compared with the other two diagnostic groups.
Conclusion The Impact on Sibling scale is a brief set of items that can help identify siblings who are negatively affected by a brother/sister's illness. Findings support further research on the Impact on Sibling scale, particularly with families of children with chronic illnesses. 相似文献
Methods Participants were 122 parents of a child with chronic illness, developmental disability, or autism spectrum disorder, and a well sibling aged 4–13 years. Parents completed the Impact on Sibling scale and the Child Behavior Checklist about the sibling, and completed the revised Impact on Family scale and the Brief Symptom Inventory about themselves.
Results The Impact on Sibling score was correlated with measures of sibling, parent and family functioning. The internal consistency of the Impact on Sibling scale was higher for families with children with chronic illness compared with the other two diagnostic groups.
Conclusion The Impact on Sibling scale is a brief set of items that can help identify siblings who are negatively affected by a brother/sister's illness. Findings support further research on the Impact on Sibling scale, particularly with families of children with chronic illnesses. 相似文献
8.
9.
L R Kao C F Wilkinson 《Xenobiotica; the fate of foreign compounds in biological systems》1987,17(7):793-805
1. Inhibitory activity of dihydrosafrole towards benzo[a]pyrene (BP) hydroxylase activity in hepatic microsomes from beta-naphthoflavone (BNF)-induced rats, and in reconstituted systems containing cytochrome P-450c, increased dramatically on preincubation of the inhibitor with NADPH; no inhibition occurred without preincubation. The level of BP hydroxylase inhibition was associated with the progressive formation of the 456 nm dihydrosafrole metabolite-cytochrome P-450c spectral complex during preincubation. 2. Inhibition of BP hydroxylase by dihydrosafrole in control microsomes, and inhibition of ethoxyresorufin O-deethylase (EROD) in microsomes (control or BNF-induced) and in reconstituted systems with cytochrome P-450c, did not require preincubation and apparently was not dependent on prior formation of the dihydrosafrole metabolite-cytochrome P-450 complex. 3. Kinetic studies established that, following preincubation with NADPH, dihydrosafrole was a noncompetitive inhibitor of both BP hydroxylase and EROD activities. In the absence of preincubation, dihydrosafrole was an effective competitive inhibitor of EROD in BNF-induced microsomes and in reconstituted systems with cytochrome P-450c. 4. Both ethoxyresorufin and benzo[a]pyrene inhibited the development of the type I optical difference spectrum of dihydrosafrole in reconstituted systems containing cytochrome P-450c. Inhibition by ethoxyresorufin was competitive while that caused by benzo[a]pyrene was noncompetitive in nature. 5. The type II ligand phenylimidazole was an effective noncompetitive inhibitor of EROD activity but failed to exert any inhibitory effect on cytochrome P-450c-mediated BP hydroxylase activity. Phenylimidazole inhibited formation of the dihydrosafrole type I optical difference spectrum non-competitively. 6. The results indicate that ethoxyresorufin and benzo[a]pyrene may occupy different binding sites on cytochrome P-450c and that dihydrosafrole binds primarily to the site utilized by ethoxyresorufin. 相似文献
10.
Shah-Hwa Chou Eing-Long Kao Chien-Chih Lin Meei-Feng Huang 《Clinical autonomic research》2006,16(3):240-242
A total of 114 patients with various sympathetic disorders underwent endoscopic sympathetic block over different thoracic
ganglions by the clipping method. The advantages of this method include the recognition of the clipped level, changeability,
and reversibility. However, 4.4% of patients were unilaterally clipped at the wrong level. 相似文献