全文获取类型
收费全文 | 1285篇 |
免费 | 141篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 20篇 |
儿科学 | 28篇 |
妇产科学 | 13篇 |
基础医学 | 147篇 |
口腔科学 | 8篇 |
临床医学 | 195篇 |
内科学 | 266篇 |
皮肤病学 | 23篇 |
神经病学 | 110篇 |
特种医学 | 35篇 |
外科学 | 155篇 |
综合类 | 14篇 |
一般理论 | 1篇 |
预防医学 | 83篇 |
眼科学 | 10篇 |
药学 | 221篇 |
中国医学 | 1篇 |
肿瘤学 | 97篇 |
出版年
2021年 | 24篇 |
2020年 | 14篇 |
2019年 | 25篇 |
2018年 | 32篇 |
2017年 | 17篇 |
2016年 | 32篇 |
2015年 | 27篇 |
2014年 | 36篇 |
2013年 | 45篇 |
2012年 | 73篇 |
2011年 | 64篇 |
2010年 | 31篇 |
2009年 | 29篇 |
2008年 | 56篇 |
2007年 | 70篇 |
2006年 | 69篇 |
2005年 | 75篇 |
2004年 | 58篇 |
2003年 | 62篇 |
2002年 | 53篇 |
2001年 | 50篇 |
2000年 | 52篇 |
1999年 | 36篇 |
1998年 | 10篇 |
1996年 | 12篇 |
1995年 | 12篇 |
1994年 | 12篇 |
1993年 | 10篇 |
1992年 | 34篇 |
1991年 | 15篇 |
1990年 | 17篇 |
1989年 | 20篇 |
1988年 | 12篇 |
1987年 | 15篇 |
1986年 | 10篇 |
1985年 | 17篇 |
1984年 | 12篇 |
1983年 | 11篇 |
1979年 | 9篇 |
1978年 | 12篇 |
1975年 | 9篇 |
1974年 | 9篇 |
1973年 | 9篇 |
1972年 | 8篇 |
1971年 | 11篇 |
1970年 | 12篇 |
1969年 | 10篇 |
1968年 | 8篇 |
1967年 | 12篇 |
1966年 | 12篇 |
排序方式: 共有1427条查询结果,搜索用时 31 毫秒
1.
The aim of this review article is to discuss the electrocardiographic presentation of the so called variants of pre‐excitation (“Mahaim fibers”) during sinus rhythm and tachycardia. 相似文献
2.
Five hybridoma cell lines were established that secrete monoclonal antibodies (MAbs) directed against rat plasma low molecular weight plasma kininogen. Two of the secreted antibodies were of the IgG1k isotype. The remaining three were of the IgG1 lambda, IgG2ak and IgMk isotypes, respectively. The dissociation constants (Kd) of these MAbs ranged from 0.58 X 10(-9) M to 5.4 X 10(-9) M. At least two distinct epitopes on the rat plasma kininogen were recognized by these MAbs. Further characterization of the MAbs showed that four MAbs cross-reacted strongly with kininogen from the Murphy-Sturm lymphosarcoma (MSLS) tumor while one of the MAbs cross-reacted weakly with MSLS tumor kininogen. 相似文献
3.
Neuronal plasticity can manifest itself in alterations in the sensitivity of memory to the effects of drugs. After the production of a brain lesion, the memory processing of a passive-avoidance task in mice gradually becomes sensitive to the effect of morphine, i.e., an improvement in retention performance is seen after 6 weeks, but not after 1 or 2 weeks. The results presented demonstrate that, even if they lead to no discernible changes in behaviour, plastic processes can still be detected by means of behavioural tests. 相似文献
4.
W Kuhnz G al-Yacoub J Power S E Ormesher D J Back G Jütting 《Arzneimittel-Forschung》1992,42(9):1142-1146
The serum concentrations of 3-keto-desogestrel have been measured in 43 women who took a low-dose oral contraceptive containing 30 micrograms ethinyl estradiol (CAS 57-63-6) together with 150 micrograms desogestrel (CAS 54024-22-5) for a period of 3 months. Basic pharmacokinetic parameters, like Cmax, tmax and AUC, as well as the serum protein binding of 3-keto-desogestrel were determined on days 1, 10 and 21 of the first and the third treatment cycle, respectively. During cycle one, Cmax, AUC(0-4h) and AUC(0-24h) values on day 1 were 1.9 +/- 0.7 ng/ml, 3.9 +/- 1.3 ng.ml-1.h and 12.4 +/- 5.7 ng.ml-1.h, respectively. These values increased to 4.7 +/- 2.0 ng/ml, 12.1 +/- 5.6 ng.ml-1.h and 47.3 +/- 26.0 ng.ml-1.h on day 21. Within cycle 3, a similar, although less steep increase was observed for these parameters and there was practically no difference in the values of corresponding parameters on day 21 of both cycles. Throughout treatment, there was a redistribution of 3-keto-desogestrel with respect to the binding proteins albumin and sex hormone binding globulin (SHBG). During cycle 1, the free fraction decreased from 1.8% on day 1 to 1.1% on day 21, and the SHBG-bound fraction increased at the same time from 40% to 62%, mainly at the expense of the albumin-bound fraction. During cycle 3, there were only minor changes as compared to cycle one. The observed changes in the serum protein binding were related to an increase in SHBG levels during the treatment period. 相似文献
5.
6.
F. Rensch B. Harder M. Goebeler W. Back J.B. Jonas Dr. F. Schlichtenbrede 《Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft》2009,106(8):735-739
Brooke’s syndrome is a rare autosomal dominant dermatosis characterized by multiple trichoepitheliomas, which preferentially arise in the face. Therapy consists of excisional surgery of larger tumors and for multiple lesions, dermal abrasion or laser therapy may be considered. Patients with Brooke’s syndrome should be closely followed-up due to the possible development of malignant skin tumours. Here, we present a patient with Brooke’s syndrome and report on the course of treatment. 相似文献
7.
Comparative genomic hybridization (CGH) discloses chromosomal and subchromosomal copy number changes in Merkel cell carcinomas 总被引:1,自引:0,他引:1
M. Härle N. Arens I. Moll W. Back T. Schulz H. Scherthan 《Journal of cutaneous pathology》1996,23(5):391-397
We analyzed three Merkel cell carcinomas (MCC), applying comparative genomic hybridization (CGH) with DNA from paraffin-embedded and cultured tumor material as the probes. By this method, numerous changes in chromosome copy numbers were observed in each tumor investigated. Recurrent gains of chromosomes 1, 6, 18q and 20 were detected in two tumors. A third tumor showed complex chromosomal copy number changes, including gain of chromosome 8 and 9. These gains, as well as gain of chromosome 1 in the first two tumors, were confirmed by fluorescence in situ hybridization to paraffin tissue sections. Our results support the view that important genes for MCC development may be located on chromosomes 1, 6, 18q and 20. 相似文献
8.
9.
10.