首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   17976篇
  免费   1025篇
  国内免费   66篇
耳鼻咽喉   245篇
儿科学   464篇
妇产科学   365篇
基础医学   2524篇
口腔科学   373篇
临床医学   1630篇
内科学   3529篇
皮肤病学   524篇
神经病学   2232篇
特种医学   1038篇
外科学   2535篇
综合类   131篇
一般理论   4篇
预防医学   916篇
眼科学   298篇
药学   956篇
中国医学   65篇
肿瘤学   1238篇
  2023年   150篇
  2022年   248篇
  2021年   444篇
  2020年   296篇
  2019年   419篇
  2018年   451篇
  2017年   415篇
  2016年   503篇
  2015年   504篇
  2014年   704篇
  2013年   859篇
  2012年   1359篇
  2011年   1430篇
  2010年   819篇
  2009年   719篇
  2008年   1175篇
  2007年   1169篇
  2006年   1124篇
  2005年   1111篇
  2004年   959篇
  2003年   917篇
  2002年   824篇
  2001年   180篇
  2000年   144篇
  1999年   194篇
  1998年   196篇
  1997年   141篇
  1996年   141篇
  1995年   99篇
  1994年   96篇
  1993年   65篇
  1992年   64篇
  1991年   71篇
  1990年   47篇
  1989年   35篇
  1988年   48篇
  1987年   42篇
  1986年   37篇
  1985年   45篇
  1984年   32篇
  1983年   25篇
  1982年   38篇
  1981年   29篇
  1980年   40篇
  1979年   28篇
  1978年   26篇
  1977年   33篇
  1976年   18篇
  1975年   17篇
  1973年   21篇
排序方式: 共有10000条查询结果,搜索用时 716 毫秒
1.
Klawitter  Felix  Walter  Uwe  Axer  Hubertus  Ehler  Johannes 《Der Anaesthesist》2023,72(8):543-554
Die Anaesthesiologie - Die Intensive Care Unit-Acquired Weakness (ICUAW) stellt eine der häufigsten neuromuskulären Komplikationen in der Intensivmedizin dar. Besonders bei...  相似文献   
2.
3.
4.
5.
6.

Objective

To assay peripheral inter-ictal cytokine serum levels and possible relations with non-invasive vagus nerve stimulation (nVNS) responsiveness in migraineurs.

Methods

This double-blinded, sham-controlled study enrolled 48 subjects and measured headache severity, frequency [headache days/month, number of total and mild/moderate/severe classified attacks/month], functional state [sleep, mood, body weight, migraine-associated disability] and serum levels of inflammatory markers [inter-ictal] using enzyme-linked immunoassays at baseline and after 2 months of adjunctive nVNS compared to sham stimulation and suitably matched controls.

Results

No significant differences were observed at baseline and after 2 months for headache severity, total attacks/month, headache days/month and functional outcome [sleep, mood, disability] between verum and sham nVNS. However, the number of severe attacks/month significantly decreased in the verum nVNS group and circulating pro-inflammatory IL-1β was elevated significantly in the sham group compared to nVNS. Levels of anti-inflammatory IL-10 were significantly higher at baseline in both groups compared to healthy controls, but not at 2 months follow-up [p?<?0.05]. Concentrations of high-mobility group box-1 (HMGB-1), IL-6, tumor-necrosis factor-α (TNF-α), leptin, adiponectin, ghrelin remained unchanged [p?>?0.05]. No severe device-/stimulation-related adverse events occurred.

Conclusion

2 months of adjunctive cervical nVNS significantly declined the number of severe attacks/month. Pro-inflammatory IL-1β plasma levels [inter-ictal] were higher in sham-treated migraine patients compared to verum nVNS. However, pro- [IL-6, HMGB-1, TNF-α, leptin] and anti-inflammatory [IL-10, adiponectin, ghrelin] mediators did not differ statistically. Profiling of neuroinflammatory circuits in migraine to predict nVNS responsiveness remains an experimental approach, which may be biased by pre-analytic variables warranting large-scale biobank-based systematic investigations [omics].  相似文献   
7.
8.
9.
Objective: A multidisciplinary vocational rehabilitation programme, the Vocational Enablement Protocol (VEP) was developed to address the specific needs of employees with hearing difficulties. In the current study we evaluated the process of implementing the VEP in audiologic care among employees with hearing impairment. Design: In conjunction with a randomized controlled trial, we collected and analysed data on seven process parameters: recruitment, reach, fidelity, dose delivered, dose received and implemented, satisfaction, and perceived benefit. Study sample: Sixty-six employees with hearing impairment participated in the VEP. The multidisciplinary team providing the VEP comprised six professionals. Results: The professionals performed the VEP according to the protocol. Of the recommendations delivered by the professionals, 31% were perceived as implemented by the employees. Compliance rate was highest for hearing-aid uptake (51%). Both employees and professionals were highly satisfied with the VEP. Participants rated good perceived benefit from it. Conclusions: Our results indicate that the VEP could be a useful treatment for employees with hearing difficulties from a process evaluation perspective. Implementation research in the audiological setting should be encouraged in order to further provide insight into parameters facilitating or hindering successful implementation of an intervention and to improve its quality and efficacy.  相似文献   
10.
Abstract

Purpose: We examined underlying psychosocial processes of a behavioral treatment for urinary incontinence (UI) of prostate cancer survivors.

Design: Secondary analysis of data collected from a clinical trial.

Sample: Two hundred forty-four prostate cancer survivors who participated in a clinical trial of behavioral intervention to UI as intervention or control subjects.

Methods: The participants had a 3-month behavioral intervention or usual care and were followed up for an additional 3?months. They were assessed at baseline, 3, and 6?months. Latent growth curve models were performed to examine trajectories of each study variable and relationships among the variables.

Findings: Increasing self-efficacy and social support were significantly and independently associated with more reduction of urinary leakage frequency over time.

Implications for psychosocial oncology: Providing problem-solving skills and social support, including peer support, are essential for empowering patients to reduce UI.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号