全文获取类型
收费全文 | 165篇 |
免费 | 12篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 3篇 |
妇产科学 | 1篇 |
基础医学 | 17篇 |
口腔科学 | 8篇 |
临床医学 | 18篇 |
内科学 | 62篇 |
皮肤病学 | 7篇 |
神经病学 | 1篇 |
特种医学 | 16篇 |
外科学 | 13篇 |
综合类 | 4篇 |
预防医学 | 10篇 |
药学 | 6篇 |
肿瘤学 | 10篇 |
出版年
2023年 | 1篇 |
2022年 | 2篇 |
2021年 | 3篇 |
2020年 | 3篇 |
2019年 | 4篇 |
2018年 | 4篇 |
2017年 | 6篇 |
2016年 | 2篇 |
2015年 | 2篇 |
2014年 | 4篇 |
2013年 | 9篇 |
2012年 | 10篇 |
2011年 | 12篇 |
2010年 | 1篇 |
2009年 | 9篇 |
2008年 | 7篇 |
2007年 | 11篇 |
2006年 | 11篇 |
2005年 | 5篇 |
2004年 | 7篇 |
2003年 | 5篇 |
2002年 | 3篇 |
2001年 | 2篇 |
1999年 | 2篇 |
1998年 | 4篇 |
1997年 | 7篇 |
1996年 | 8篇 |
1995年 | 4篇 |
1993年 | 4篇 |
1992年 | 2篇 |
1990年 | 1篇 |
1989年 | 1篇 |
1988年 | 1篇 |
1986年 | 1篇 |
1984年 | 1篇 |
1983年 | 3篇 |
1982年 | 1篇 |
1980年 | 2篇 |
1978年 | 3篇 |
1977年 | 2篇 |
1976年 | 5篇 |
1975年 | 2篇 |
排序方式: 共有177条查询结果,搜索用时 31 毫秒
1.
2.
3.
4.
Identification of the multiple endocrine neoplasia type 1 (MEN1) gene. The European Consortium on MEN1 总被引:10,自引:0,他引:10
Lemmens I; Van de Ven WJ; Kas K; Zhang CX; Giraud S; Wautot V; Buisson N; De Witte K; Salandre J; Lenoir G; Pugeat M; Calender A; Parente F; Quincey D; Gaudray P; De Wit MJ; Lips CJ; Hoppener JW; Khodaei S; Grant AL; Weber G; Kytola S; Teh BT; Farnebo F; Thakker RV 《Human molecular genetics》1997,6(7):1177-1183
5.
Increased mucosal inflammatory cytokines in children with Helicobacter pylori-associated gastritis 总被引:2,自引:0,他引:2
N Kütükçüler S Aydogdu D Göksen S çaglayan RV Yagcyi 《Acta paediatrica (Oslo, Norway : 1992)》1997,86(9):928-931
The concentrations of tumour necrosis factor-alpha (TNF-α), interleukin-6 (IL-6) and IL-1-β in tissue homogenates of gastric mucosal biopsy specimens, and in gastric juice samples from Helicobacter pylori-positive and -negative children, were determined. The study population comprised 30 children with recurrent abdominal pain attending upper gastrointestinal endoscopy. Of these patients 18 were infected with H. pylori. Cytokine concentrations in gastric biopsy homogenate supernatants and in gastric juice were measured by enzyme-linked immunosorbent assay (ELISA). TNF-α levels in gastric juice and in gastric biopsy homogenate supernatants in patients with H. pylori-positive gastritis were found to be significantly higher than those in children without H. pylori infection. IL-6 levels were also higher in H. pylori -infected subjects, but the difference in IL-6 concentrations measured in gastric juice and biopsy homogenate supernatants did not reach statistical significance. IL-1-β concentrations in both specimens showed no significant difference between the two groups of children. It was suggested that increased levels of inflammatory cytokines, especially TNF-α and IL-6 generated locally within the gastric mucosa might be implicated in the pathogenesis of H. pylori-associated gastritis in childhood. 相似文献
6.
7.
Robert Zilberszac Rishi Chandiramani Christian Hengstenberg Samantha Sartori Davide Cao Jaya Chandrasekhar Ulrich Schafer Didier Tchetche Roberto Violini Raban Jeger Eric Van Belle Peter Boekstegers Rainer Hambrecht Christophe Tron Nicolas Dumenteil Axel Linke Jurriën M. ten Berg Efthymios N. Deliargyris Prodromos Anthopoulos Roxana Mehran George Dangas 《Catheterization and cardiovascular interventions》2020,96(3):E377-E386
8.
Jeger RV 《Minerva cardioangiologica》2012,60(1):101-109
Cardiogenic shock is a serious complication of acute myocardial infarction and occurs as a consequence of acute left ventricular failure and subsequent inappropriate tissue perfusion. While its incidence has been reported to be as high as 10% in the late 90ties, it has been steadily declining to currently less than 6% since the implementation of early revascularization as a class I indication in current guidelines. Despite recent advances in the treatment of cardiogenic shock, mortality is still high at approximately 50%. Current therapeutic approaches include early revascularization, fluid resuscitation, inotropic and vasopressor therapy, and mechanical circulatory support using intra-aortic balloon counterpulsation or percutaneous left ventricular assist devices. Novel treatment options such as specific inhibitors of inducible nitric oxide synthase or newer developments in mechanical circulatory support might be beneficial and should be tested in adequately powered randomized trials. However, difficulties in enrolling cardiogenic shock patients in randomized controlled trials are considerable. Until more data are available, cardiogenic shock patients should be treated aggressively with early revascularization and mechanical circulatory support to increase their probability of survival. 相似文献
9.
10.