全文获取类型
收费全文 | 14990篇 |
免费 | 854篇 |
国内免费 | 58篇 |
专业分类
耳鼻咽喉 | 129篇 |
儿科学 | 386篇 |
妇产科学 | 193篇 |
基础医学 | 2470篇 |
口腔科学 | 357篇 |
临床医学 | 1325篇 |
内科学 | 2969篇 |
皮肤病学 | 337篇 |
神经病学 | 1530篇 |
特种医学 | 797篇 |
外科学 | 2050篇 |
综合类 | 68篇 |
一般理论 | 3篇 |
预防医学 | 823篇 |
眼科学 | 301篇 |
药学 | 1110篇 |
中国医学 | 22篇 |
肿瘤学 | 1032篇 |
出版年
2023年 | 52篇 |
2022年 | 122篇 |
2021年 | 263篇 |
2020年 | 160篇 |
2019年 | 225篇 |
2018年 | 311篇 |
2017年 | 218篇 |
2016年 | 312篇 |
2015年 | 381篇 |
2014年 | 497篇 |
2013年 | 574篇 |
2012年 | 945篇 |
2011年 | 923篇 |
2010年 | 579篇 |
2009年 | 593篇 |
2008年 | 846篇 |
2007年 | 914篇 |
2006年 | 953篇 |
2005年 | 952篇 |
2004年 | 914篇 |
2003年 | 889篇 |
2002年 | 792篇 |
2001年 | 230篇 |
2000年 | 186篇 |
1999年 | 181篇 |
1998年 | 236篇 |
1997年 | 145篇 |
1996年 | 123篇 |
1995年 | 121篇 |
1994年 | 111篇 |
1993年 | 95篇 |
1992年 | 115篇 |
1991年 | 87篇 |
1990年 | 95篇 |
1989年 | 96篇 |
1988年 | 80篇 |
1987年 | 77篇 |
1986年 | 81篇 |
1985年 | 74篇 |
1984年 | 82篇 |
1983年 | 65篇 |
1982年 | 62篇 |
1981年 | 48篇 |
1980年 | 68篇 |
1979年 | 65篇 |
1978年 | 51篇 |
1977年 | 44篇 |
1976年 | 57篇 |
1973年 | 43篇 |
1954年 | 35篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
1.
2.
Michels Guido Horn Rudolf Helfen Andreas Hagendorff Andreas Jung Christian Hoffmann Beatrice Jaspers Natalie Kinkel Horst Greim Clemens-Alexander Knebel Fabian Bauersachs Johann Busch Hans-Jörg Kiefl Daniel Spiel Alexander O. Marx Gernot Dietrich Christoph F. 《Der Anaesthesist》2022,71(4):307-310
Die Anaesthesiologie - 相似文献
3.
4.
5.
Joachim Fensterle 《Journal der Deutschen Dermatologischen Gesellschaft》2006,4(3):205-216
Many cellular signaling pathways are involved in the development of cancer. Depending on the tumor entity, the nature as well as the mode of activation can differ. Some signaling pathways frequently show changes as all tumor cells have to fulfill some basic requirements such as independence from growth factors or insensitivity against apoptosis. In this review, the possibilities of a tumor to manipulate signaling pathways to reach these goals are exemplified based on an archetypical melanoma cell. In addition, new therapeutic options based on the knowledge of signaling pathways will be discussed. 相似文献
6.
Robert A. Mischkowski Max J. Zinser Alexander C. Kübler Barbara Krug Ulrich Seifert Joachim E. Zller 《Journal of cranio-maxillo-facial surgery》2006,34(8):478-483
BACKGROUND: An augmented reality tool for computer assisted surgery named X-Scope allows visual tracking of real anatomical structures in superposition with volume rendered CT or MRI scans and thus can be used for navigated translocation of bony segments. METHODS: In a feasibility study X-Scope was used in orthognathic surgery to control the translocation of the maxilla after Le Fort I osteotomy within a bimaxillary procedure. The situation achieved was compared with the pre-operative situation by means of cephalometric analysis on lateral and frontal cephalograms. RESULTS: The technique was successfully utilized in 5 patients. Maxillary positioning using X-Scope was accomplished accurately within a range of 1mm. The tool was used in all cases in addition to the usual intra-operative splints. A stand-alone application without conventional control does not yet seem reasonable. CONCLUSION: Augmented reality tools like X-Scope may be helpful for controlling maxillary translocation in orthognathic surgery. The application to other interventions in cranio-maxillofacial surgery such as Le Fort III osteotomy, fronto-orbital advancement, and cranial vault reshaping or repair may also be considered. 相似文献
7.
Joachim Dissemond Andreas Krber Stephan Grabbe 《Journal der Deutschen Dermatologischen Gesellschaft》2006,4(8):627-634
In Germany about 0.7 % of the adult population have a chronic leg ulcer. Although chronic venous insufficiency accounts for at least 80 % of all chronic leg ulcers, knowledge of the relevant differential diagnostic considerations is of crucial importance, in particular for patients who are refractory to therapy. In addition to vascular disease, other causes include neuropathic, metabolic, hematologic and exogenous factors as well as neoplasias, infections, drugs, genetic defects and some primary skin disorders. For the long‐term successful treatment of patients with chronic leg ulcers, it is necessary to identify all relevant factors, in order to enable a pathogenesis‐oriented, interdisciplinary therapeutic approach. 相似文献
8.
Dr. Med. Wolfgang Rutsch Horst Schmutzler 《Cardiovascular and interventional radiology》1986,9(5-6):245-252
Reestablishing myocardial perfusion during evolving myocardial infarction may limit the ultimate extent of infarction if viable
myocardial tissue is present when recanalization of the occluded vessel is achieved. This will result in improved left ventricular
function and decreased mortality. In addition to their therapeutic benefits, recanalization procedures have contributed greatly
to our knowledge of acute myocardial infarction. It has been demonstrated that myocardial infarction most often occurs after
thrombotic occlusion of a coronary artery. This has settled a controversy that has preoccupied cardiologists for decades.
Selective intracoronary administration of fibrinolytic agents is followed by recanalization in approximately 80% of cases.
Therapeutic failures are attributable to occlusion caused by other factors, to inactivation of streptokinase by high antibody
concentrations, and to insufficient concentrations of streptokinase at the thrombus as a results of unfavorable flow conditions.
This study is dedicated to Prof. Dr. Med. Horst Schmutzler on the occasion of his 60th birthday. 相似文献
9.
Matthias Müller Joachim Berger Nikolaus Gersdorff Francesco Cecconi Rainer Herken Fabio Quondamatteo 《Developmental dynamics》2005,234(1):215-221
Apoptosis is an essential ubiquitous process that controls the duration of the life span of cells, thus playing a crucial role in morphogenetic, histogenetic, and phylogenetic developmental processes. Apaf1 (apoptosis protease activating factor 1) is one of the central mediators of the intrinsic apoptotic pathway and a part of the apoptosome, which activates procaspase-3 and promotes cell death. Gene knockout of Apaf1 in mice leads to late embryonic lethality with malformations such as the persistence of interdigital webs and hyperplasia of brain and retina. Therefore, Apaf1 is generally believed to play a crucial role in developmental apoptosis and have a widespread expression. However, its pattern of expression in early development remains unknown. To specify whether Apaf1 indeed plays this key role, we investigated the pattern of gene expression for Apaf1 in mouse embryos on day 7, 9, and 12 of development. Our results show, that gene expression for Apaf1 first occurs within the embryo between day 7 and 9 of development, becoming more widespread toward day 12 and then includes structures, such as yolk sac, mesenchyme, cartilage, heart anlage, otic vesicle, peridermis, and anlagen of the spinal ganglia and vertebral bodies. Our results also show that gene expression for Apaf1 is not ubiquitous in early mouse development. This finding indicates that cell death processes are independent of or less dependent on Apaf1 during this time. Of interest, an active gene expression for Apaf1 is also present in organ anlagen such as heart or intestine, in which no obvious phenotype is seen after Apaf1 deletion. This finding suggests a possible role for Apaf1 in such anlagen as a putative alternative compensatory pathway, which could be switched on in the case of defects in the mediators that are normally involved in such organs. 相似文献
10.
Torsten T. Bauer Joachim Lorenz Klaus-Friedrich Bodmann Friedrich Vogel 《Medizinische Klinik》2005,26(13):355-360