全文获取类型
收费全文 | 756篇 |
免费 | 27篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 7篇 |
妇产科学 | 9篇 |
基础医学 | 50篇 |
口腔科学 | 22篇 |
临床医学 | 68篇 |
内科学 | 283篇 |
皮肤病学 | 4篇 |
神经病学 | 33篇 |
特种医学 | 16篇 |
外科学 | 199篇 |
综合类 | 4篇 |
预防医学 | 6篇 |
眼科学 | 15篇 |
药学 | 21篇 |
中国医学 | 1篇 |
肿瘤学 | 42篇 |
出版年
2022年 | 2篇 |
2021年 | 6篇 |
2020年 | 7篇 |
2019年 | 3篇 |
2018年 | 8篇 |
2017年 | 6篇 |
2016年 | 12篇 |
2015年 | 15篇 |
2014年 | 6篇 |
2013年 | 15篇 |
2012年 | 29篇 |
2011年 | 43篇 |
2010年 | 17篇 |
2009年 | 24篇 |
2008年 | 39篇 |
2007年 | 44篇 |
2006年 | 53篇 |
2005年 | 44篇 |
2004年 | 41篇 |
2003年 | 55篇 |
2002年 | 43篇 |
2001年 | 27篇 |
2000年 | 27篇 |
1999年 | 25篇 |
1998年 | 7篇 |
1997年 | 5篇 |
1996年 | 4篇 |
1995年 | 3篇 |
1994年 | 5篇 |
1993年 | 8篇 |
1992年 | 8篇 |
1991年 | 12篇 |
1990年 | 10篇 |
1989年 | 14篇 |
1988年 | 13篇 |
1987年 | 13篇 |
1986年 | 19篇 |
1985年 | 10篇 |
1984年 | 9篇 |
1983年 | 14篇 |
1982年 | 6篇 |
1979年 | 6篇 |
1978年 | 2篇 |
1977年 | 4篇 |
1975年 | 4篇 |
1974年 | 2篇 |
1973年 | 2篇 |
1972年 | 2篇 |
1970年 | 2篇 |
1913年 | 1篇 |
排序方式: 共有783条查询结果,搜索用时 15 毫秒
1.
S Sakai Y Ito T Koide K Tei A Hara H Sawada 《Hinyokika kiyo. Acta urologica Japonica》1986,32(3):337-341
A new method of determining urinary polyamine concentration was compared with other techniques, namely, high pressure liquid chromatography (HPLC) and a polyamine test-enzyme kit. The values obtained by the new method, HPLC, and polyamine test-enzyme kit correlated well for all the fractions: diamine, spermidine and spermine. The correlation between the new method and the polyamine test-enzyme kit gave r = 0.9702, y = 1.1359x + 5.1266 (n = 48). 相似文献
2.
3.
Mikio Mikami Chisei Tei Kyoko Takehara Shinichi Komiyama Atsushi Suzuki Takanori Hirose 《International journal of gynecological pathology》2003,22(2):205-208
A 38-year-old female presented with a lower abdominal mass. During the operation the mass was found to be retroperitoneal and was excised. Gross examination revealed a mucin-containing cystic lesion with a mural nodule. On microscopic examination, the cystic areas were lined by an invasive mucinous adenocarcinoma and the nodule was composed of an anaplastic sarcomatoid tumor that was immunoreactive for cytokeratin. This present case is the 21st example of a retroperitoneal primary mucinous cystadenocarcinoma and the fourth with a mural nodule. Three of four cases with a mural nodule, including our case, had a rapidly fatal outcome. 相似文献
4.
Cultured human arterial smooth muscle cells produced an immunologically specific renin-like enzyme. The renin-like enzyme in the culture medium was mostly an inactive form; the proportion of the active form in the cell was 30 to 75%. Phorbol 12-myristate 13-acetate, N'-O'-dibutylyladenosine 3', 5'-monophosphate and isoproterenol with theophylline increased the renin-like enzyme in the medium and in the cell, dose dependently. Endothelial cell growth supplement also increased the renin-like enzyme produced by cultured vascular smooth muscle cells, and heparin promoted the effects of endothelial cell growth supplement. The existence of the regulation of the renin-like enzyme produced by cultured vascular smooth muscle cells strongly suggests the existence of a local renin angiotensin system in human vascular walls. 相似文献
5.
Y Kusama F Takiguchi H Tei N Hata F Otsu M Ohta K Munakata H Kishida H Hayakawa H Okumura 《Japanese heart journal》1988,29(2):243-248
A 48-year-old man had histologically demonstrated cardiac involvement associated with progressive muscular dystrophy. On coronary arteriography, numerous vascular communications between the coronary arteries and the left ventricular chamber were found. These vascular communications are considered to be the arterioluminal vessels. This is the first report of a case of progressive muscular dystrophy with numerous arterioluminal vessels. 相似文献
6.
Hajime Kazamatsuri M.D. Tetsuya Hirose M.D. Osamu Kanno M.D. Nobumasa Kato M.D. Hiromoto Yasuda 《Psychiatry and clinical neurosciences》1994,48(4):869-879
Abstract: Two autopsied female sibling cases of sudanophilic leukodystrophy are reported. Case A and case B were the second and third of seven siblings, and a sister and a brother died from severe progressive neurological disease with similar symptoms. Consanguineous marriages were noted in the family of both cases through the past three generations. Case A gradually developed intellectual deterioration and tetraplegia at the age of 29, progressed to akinetic mutism within one year and thereafter survived for 14 years. Neuropathologically, a severe atrophy and degeneration were noted in the white matter of the whole cerebrum, sparing the subcortical U-fibers. Myelin and axons were severely damaged with peripheral astrocytic gliosis. Case B developed similar clinical symptoms at the age of 20 and survived for 7 years in the state of akinetic mutism. Similar postmortem findings as those of case A were found in the white matter of the cerebrum with formation of sudanophilic breakdown products and with thick fibrillary gliosis. The pyramidal tract was completely degenerated. There was no accumulation of abnormal lipid in the brains of both cases. 相似文献
7.
8.
S. Lindstrom A. Endo S. Sugita M. Pecoraro Y. Hiromoto M. Kamada T. Takahashi K. Nerome 《Archives of virology》1998,143(8):1585-1598
Summary. Matrix (M) and nonstructural (NS) genes of thirteen equine H3N8 and H7N7 influenza viruses were sequenced and analyzed from
an evolutionary point of view. The M and NS genes of H3N8 viruses isolated between 1989 and 1993 evolved into two minor branch
clusters, including isolates from Europe and the American continent, respectively. It was noteworthy to reveal that the nucleotide
sequences of the M and NS genes of an earlier American strain showed highest homology to those of recent European viruses.
“Frozen evolution” was observed in the M and NS genes of A/eq/LaPlata/1/88. It was also evident that the NS gene of an H7N7
virus from 1977 was very similar to that of a 1979-H3N 8 virus, while the M gene was closest phylogenetically to that of the
earliest H7N7 virus isolated in 1956. Furthermore, the M2 protein of A/eq/Newmarket/1/77 virus contained a carboxyl terminal
deletion of three amino acids. The evolutionary rates of the M and NS genes of H3N8 equine influenza viruses were estimated
to be 5.4 × 10−4 and 5.1 × 10−4 substitutions per site per year, respectively, which were slower than those of human viruses.
Received November 21, 1997 Accepted March 9, 1998 相似文献
9.
Iwashita T Mori H Ito Y Obashi A Sugimoto K Tei H Hirata I Oshiba S 《Pathology international》1996,46(3):204-210
Colorectal neoplasms obtained at colonoscopy were examined by argyrophilic nucleolar organizer region (AgNOR) staining to evaluate the usefulness of AgNOR as a discriminant for malignancy. AgNOR dots were divided into two kinds: 'structures' (larger and less-densely stained) corresponding to the nucleolus, and 'units' (smaller and densely stained) presumed to be true AgNOR within the structure. The number of structures per nucleus did not differ between the adenoma and carcinoma groups, whereas the number of units per nucleus showed a significant difference. However there were several cases showing an overlap between the adenoma and carcinoma groups, leading to a difficulty in deciding whether any given case was benign or malignant. Three types of AgNOR patterns were categorized based on the ratio of units to structure. Type I was defined as the unit being indistinguishable from the structure, Type II as each structure having one to five units, and Type III as at least one structure having six or more units, irrespective of total number of units per nucleus. The colorectal lesions in which more than half of the neoplastic cells showed Type III coincided well with carcinomas histologically diagnosed, with the exception of adenomas with severe atypia. Labeling index of proliferating cell nuclear antigen (PCNA LI) differed between the adenoma and carcinoma groups with a considerable extent of overlap, and correlated to some extent with the AgNOR values. These results showed that the AgNOR staining was useful for determining malignancy and its usefulness appeared superior to PCNA LI. 相似文献
10.
R M Farnesi S Tei D Vagnetti I Di Rosa A Fagotti B Santarella 《The Anatomical record》1990,227(2):264-270
Morphogenesis of the frontal organ in Bufo bufo was examined under transmission electron microscope. Many remarkable similarities to the frontal organ of other Amphibia Anura are observed. It originates from a diverticulum in the dorsal region of the neural tube. It is egg-shaped, has an eccentric lumen, and is made up of three kinds of cells: 1) photoreceptors, which protrude into the lumen; 2) supportive cells; and 3) ganglion cells, which make synaptic contact with the photoreceptors. Peculiar to Bufo bufo is the melanin-like pigments around the light-sensitive part of the photoreceptors. These pigments may prevent light dispersion. The frontal organ in Bufo bufo starts degenerating during the early premetamorphic stages. 相似文献