全文获取类型
收费全文 | 1312篇 |
免费 | 66篇 |
国内免费 | 63篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 81篇 |
妇产科学 | 54篇 |
基础医学 | 170篇 |
口腔科学 | 32篇 |
临床医学 | 134篇 |
内科学 | 245篇 |
皮肤病学 | 29篇 |
神经病学 | 46篇 |
特种医学 | 115篇 |
外科学 | 224篇 |
综合类 | 42篇 |
预防医学 | 85篇 |
眼科学 | 14篇 |
药学 | 73篇 |
中国医学 | 2篇 |
肿瘤学 | 89篇 |
出版年
2022年 | 8篇 |
2021年 | 14篇 |
2020年 | 19篇 |
2019年 | 26篇 |
2018年 | 36篇 |
2017年 | 20篇 |
2016年 | 22篇 |
2015年 | 25篇 |
2014年 | 64篇 |
2013年 | 59篇 |
2012年 | 51篇 |
2011年 | 56篇 |
2010年 | 55篇 |
2009年 | 54篇 |
2008年 | 49篇 |
2007年 | 82篇 |
2006年 | 38篇 |
2005年 | 48篇 |
2004年 | 40篇 |
2003年 | 29篇 |
2002年 | 26篇 |
2001年 | 30篇 |
2000年 | 15篇 |
1999年 | 24篇 |
1998年 | 35篇 |
1997年 | 40篇 |
1996年 | 27篇 |
1995年 | 27篇 |
1994年 | 33篇 |
1993年 | 23篇 |
1992年 | 10篇 |
1991年 | 19篇 |
1990年 | 10篇 |
1989年 | 22篇 |
1988年 | 29篇 |
1987年 | 20篇 |
1986年 | 19篇 |
1985年 | 34篇 |
1984年 | 17篇 |
1983年 | 26篇 |
1982年 | 14篇 |
1981年 | 16篇 |
1980年 | 12篇 |
1979年 | 9篇 |
1978年 | 12篇 |
1977年 | 13篇 |
1976年 | 17篇 |
1975年 | 17篇 |
1973年 | 9篇 |
1972年 | 8篇 |
排序方式: 共有1441条查询结果,搜索用时 15 毫秒
1.
Balloon dacryocystoplasty: indications and contraindications 总被引:3,自引:0,他引:3
2.
3.
M A el-Barrawy S A Hafez S A Mokhtar M A Abou Rayan 《The Journal of the Egyptian Public Health Association》1991,66(1-2):279-289
This study evaluates the sensitivity and specificity of an enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies against Mycobacterium tuberculosis antigen. Twenty seven of the 35 patients with pulmonary tuberculosis had positive serology with an antibody titre of 10 nineteen of them had positive serology with an antibody titre of 100. All the 27 patients with positive serology were either smear or culture positive or both. Twenty six of the 35 control group had negative serology and 9 had positive serology with an antibody titre of 10. The test has a sensitivity of 77.14% and a specificity of 74.29%. 相似文献
4.
Duncan WC; Illingworth PJ; Young FM; Fraser HM 《Human reproduction (Oxford, England)》1998,13(9):2532-2540
The molecular mechanisms involved in luteolysis are still unclear in the
primate. This study aimed to investigate the effect of induced luteolysis
on the ovarian luteinizing hormone (LH) receptor and the steroidogenic
enzyme, 3beta-hydroxysteroid dehydrogenase (3beta-HSD) in the marmoset
monkey. Luteolysis was induced in the mid-luteal phase either directly by
systemic prostaglandin F2alpha (PGF2alpha), or indirectly by LH withdrawal
using systemic gonadotrophin releasing hormone antagonist (GnRHant)
treatment. The LH receptor was studied by isotopic mRNA in-situ
hybridization and in-situ ligand binding and 3beta-HSD expression was
studied using isotopic mRNA in-situ hybridization and immunohistochemistry.
Induced luteolysis was associated with a reduction in the expression of LH
receptor (P < 0.0001) and 3beta-HSD mRNA, closely followed by a
reduction in the LH receptor (P < 0.05) and 3beta-HSD protein
concentrations within 24 h. There were no differences in the findings
whether luteolysis was induced with PGF2alpha or GnRHant. This study shows
that disparate mechanisms to induce luteolysis in the primate result in an
identical rapid loss of the LH receptor and 3beta-HSD. In conclusion,
induced luteolysis leads to rapid loss of the steroidogenic pathway in
luteal cells.
相似文献
5.
HM Clink 《Journal of clinical pathology》1980,33(8):799-800
6.
7.
Chorneyko K Giesler R Sabatino D Ross C Lobo F Shuhaibar H Chen V Elavathil L Denardi F Ansari S Salama S LeBlanc V Norman G Sheridan B Riddell R 《American journal of clinical pathology》2002,117(5):783-790
Telepathology (TP) uses telecommunication linkages to electronically capture, store, retrieve, and transmit images to distant sites. We assessed the feasibility of a dynamic real-time TP system for light microscopic (LM) diagnosis of anatomic pathology specimens, including frozen sections. Six pathologists, in 2 separate periods, read a set of 160 retrospectively retrieved slides (80 of which were frozen sections) by TP and LM. Reading times were recorded. Diagnoses were compared with the reference diagnosis (established by a group of 5 independent pathologists) and graded on a scale of 0 to 2 (2, correct; 1, incorrect but no clinical impact; 0, incorrect with clinical impact). Overall, LM was more accurate than TP compared with the reference diagnosis (score, 1.68 vs 1.54). There was no difference in accuracy between frozen section and paraffin-embedded tissue. Intraobserver agreement ranged from 82.5% to 88.2%. The average reading time was 6.0 minutes for TP and 1.4 minutes for LM. During the study, reading time decreased for TP but not for LM. These results show that despite marginally lower accuracy and longer reading times, TP isfeasible for routine light microscopic diagnosis, including frozen sections. 相似文献
8.
Semen parameters and testicular pathology in men with testicular cancer and contralateral carcinoma in situ or bilateral testicular malignancies 总被引:2,自引:2,他引:2
Kliesch S; Bergmann M; Hertle L; Nieschlag E; Behre HM 《Human reproduction (Oxford, England)》1997,12(12):2830-2835
We evaluated 14 patients with bilateral testicular tumour, one-sided tumour
and contralateral carcinoma in situ (CIS) of the testis or testis tumour in
single testis with respect to their fertility. We analysed semen
parameters, serum hormones [follicle-stimulating hormone (FSH), luteinizing
hormone (LH) and testosterone], testicular sonography, testicular volumes
and testicular histology prior to further anti-cancer treatment. Ten out of
14 patients showed normal or reduced sperm concentrations, while 4/14
patients were azoospermic. Serum FSH levels showed a significant negative
correlation with sperm concentrations in patients with testicular
malignancies (r = -0.64, P = 0.025). Testicular volumes revealed a
significant positive correlation with semen parameters in patients with
testes that were affected by CIS (r = 0.733, P = 0.038). We conclude that
even bilateral testicular cancer and/or CIS do not preclude fertility and,
therefore, patients should be offered andrological investigation and
therapy, including possibly surveillance strategy or the chance for
cryopreservation of the semen prior to further treatment in order to
preserve their chances for paternity.
相似文献
9.
10.
Chromosomal aberrations and micronucleus frequency in nurses occupationally exposed to cytotoxic drugs 总被引:4,自引:1,他引:4
Anwar Wagida A.; Salama Somaia I.; Serafy Mostafa M.EI; Hemida Samia A.; Hafez Ahmed S. 《Mutagenesis》1994,9(4):315-317
In this study, we evaluated the effect of low level occupationalexposure of nurses in a medical oncology unit in Cairo, Egypt,to anticancer drugs. Twenty nurses who constantly handled thesedrugs and 20 controls, matched according to age and sex, wereexamined. Metaphase chromosomes were studied. Percentages ofmetaphases with chromosomal aberrations were significantly higher(P < 0.001) in the exposed group (6.1 ± 2.7) versusthe controls (2.6 ± 1.6). The detected chromosomal aberrationswere in the form of chromatid gaps, chromatid breaks and acentricfragments. Micronucleated peripheral blood lymphocytes werealso analyzed in cytochalasin B treated binucleated lymphocytes.There was significant increase in cells with micronuclei (P< 0.001) in nurses (10.05 ± 4.71) in comparison tothe matched control (5.42 ± 2.22) (P < 0.001). Nursesexposed to the cytotoxic drugs for 相似文献