全文获取类型
收费全文 | 857篇 |
免费 | 65篇 |
专业分类
耳鼻咽喉 | 13篇 |
儿科学 | 21篇 |
妇产科学 | 12篇 |
基础医学 | 141篇 |
口腔科学 | 12篇 |
临床医学 | 73篇 |
内科学 | 128篇 |
皮肤病学 | 32篇 |
神经病学 | 105篇 |
特种医学 | 31篇 |
外科学 | 146篇 |
综合类 | 5篇 |
预防医学 | 40篇 |
眼科学 | 95篇 |
药学 | 23篇 |
中国医学 | 2篇 |
肿瘤学 | 43篇 |
出版年
2023年 | 4篇 |
2022年 | 11篇 |
2021年 | 15篇 |
2020年 | 12篇 |
2019年 | 8篇 |
2018年 | 14篇 |
2017年 | 7篇 |
2016年 | 11篇 |
2015年 | 16篇 |
2014年 | 23篇 |
2013年 | 45篇 |
2012年 | 39篇 |
2011年 | 44篇 |
2010年 | 27篇 |
2009年 | 32篇 |
2008年 | 41篇 |
2007年 | 46篇 |
2006年 | 42篇 |
2005年 | 35篇 |
2004年 | 42篇 |
2003年 | 23篇 |
2002年 | 34篇 |
2001年 | 38篇 |
2000年 | 27篇 |
1999年 | 23篇 |
1998年 | 13篇 |
1997年 | 21篇 |
1996年 | 8篇 |
1995年 | 9篇 |
1994年 | 10篇 |
1993年 | 6篇 |
1992年 | 25篇 |
1991年 | 12篇 |
1990年 | 15篇 |
1989年 | 21篇 |
1988年 | 20篇 |
1987年 | 9篇 |
1986年 | 12篇 |
1985年 | 21篇 |
1984年 | 4篇 |
1983年 | 5篇 |
1982年 | 11篇 |
1980年 | 5篇 |
1978年 | 4篇 |
1977年 | 8篇 |
1972年 | 3篇 |
1971年 | 2篇 |
1946年 | 2篇 |
1939年 | 2篇 |
1933年 | 2篇 |
排序方式: 共有922条查询结果,搜索用时 31 毫秒
1.
2.
In premature neonates a patent ductus arteriosus causes often other complications thus the immediate closure of the patent ductus arteriosus should be preferred or recommended. Performing the surgical closure of the ductus within the incubator can avoid complications during transportation from the premature neonates intensive care unit to the operating room. 25 very small premature neonates or those with another burden in addition were operated upon in the incubator on the premature infants intensive care unit of our hospital during the period from January 1987 to April 1989. No complications occurred during the operation, especially not caused by the strange circumstances for the operating team. Wound infections because of possible bacterial contamination of the incubator or the room were not observed during the postoperative period. 相似文献
3.
R A Valdés Olmos W W ten Bokkel Huinink J C Greve C A Hoefnagel 《Clinical nuclear medicine》1992,17(3):163-167
In six patients with doxorubicin-related cardiotoxicity, the severity of decrease in left ventricle ejection fraction (LVEF) was associated with faster myocardial I-123 MIBG washout rates. In four patients with severely decreased LVEF (range 19% to 28%), the 4-hour washout rate varied from 43% to 56%. In two patients with moderate cardiotoxicity (LVEF 42% and 43%), the washout rates were 37% and 35%, respectively. In contrast, in another patient thought to have initial left ventricular dysfunction (LVEF dropped from 66% to 54%), the myocardial I-123 MIBG retention rate was not reduced (6% washout). Subsequent continuation of chemotherapy in this patient was without complication. Reduced I-123 MIBG uptake in the left ventricle generally correlated with areas with abnormal Fourier amplitude values, but in one of the patients with moderate cardiotoxicity, the I-123 MIBG uptake was not reduced in a region with loss of amplitude, indicating dysfunction but probably no myocardial denervation. Analysis of the regional myocardial retention in patients with cardiotoxicity showed no significant difference in the I-123 MIBG washout rates of both segments with or without loss of amplitude. These data suggest that in spite of a localized loss of ventricular function demonstrated by radionuclide angiocardiography, doxorubicin-related cardiotoxicity appears to be based on a global process of myocardial adrenergic derangement. 相似文献
4.
F F de Mul M H Hottenhuis P Bouter J Greve J Arends J J ten Bosch 《Journal of dental research》1986,65(3):437-440
Using a Raman microspectrometer, we have recorded Raman spectra of synthetically produced hydroxyapatite samples with varying carbonate contents. The apatites were produced from aqueous solutions at about 40 degrees C. From line-broadening values of the symmetric phosphate stretch, it was concluded that the carbonate substitution in these lattices has a maximum of 4.5 wt %. Both phosphate and hydroxyl ions seem to be involved in the carbonate substitution process. 相似文献
5.
The present study examined the false negative error rate associated with the optional use of the Retention trial the Test of Memory Malingering (TOMM). TOMM scores from 150 traumatic brain injury and 150 chronic pain patients were examined. Results indicated that early termination of the TOMM resulted in 3% of patients going undetected by the TOMM. The practical cost of this error was minimized by the inclusion of at least one other SVT. Clinical implications are discussed. 相似文献
6.
Wim Van Biesen Walter Boer Bart De Greve Clement Dequidt Denise Vijt Dirk Faict Norbert Lameire 《Peritoneal dialysis international》2004,24(3):222-230
BACKGROUND: Glucose is an accepted osmotic agent for peritoneal dialysis (PD) although it has several drawbacks. Some of these drawbacks have been addressed by the introduction of solutions with low glucose degradation products and physiological pH in dual-chambered bags. Despite this achievement, there is a need for alternative osmotic agents.This randomized clinical trial analyzes 3-month's clinical experience with a mixture of 0.6% amino acids and 1.4% glycerol. METHODS: The study was performed at the renal units of the University Hospitals Ghent, Belgium, and Utrecht, The Netherlands. Stable PD patients were randomized for either protocol A (test solution, n = 5) or protocol B (control regimen, n = 5). In both protocols, there was a run-in phase of 1 month with a dialysis regimen of 2 x 2 L 2.27% glucose solution (Dianeal; Baxter, Nivelles, Belgium), 1 x 2 L Extraneal (Baxter), and 1 x 2 L glucose solution (Dianeal). After this month-long run-in period, patients in group A received during 3 months 2 x 2 L amino acid/glycerol solution, 1 x 2 L Extraneal, and at least 1 x 2 L of a classic glucose solution. RESULTS: Glucose absorption decreased in the test group during the test phase (from 84.2 +/- 8.7 to 11.7 +/- 11.6 g/24 hours, p = 0.001). Dialysate levels of cancer antigen 125 (CA125) increased in the test group, from 17.5 +/- 11.0 to 32.4 +/- 4.6 units/L (p = 0.04), whereas, in the control group, the levels remained stable (15.5 +/- 8.7 and 14.9 +/- 9.8 units/L respectively, p = 0.4).There were no differences in serum urea, serum bicarbonate, serum osmolarity, serum albumin, or parameters related to skin-fold thickness or serum glycerol levels between control and test solutions. No differences were observed in obtained ultrafiltration after a 4-hour dwell with 2.27% glucose or the test solution, both measured at week 4 of the run-in period and week 12 of the test period. CONCLUSION: This study demonstrated that the use of a new 0.6% amino acid/1.4% glycerol-containing dialysis solution is safe and well tolerated. Glucose load was reduced significantly and dialysate CA125 levels improved significantly. Ultrafiltration was comparable with that of a 2.27% glucose solution. All these factors, in combination with the potential nutritional benefits, can contribute to a beneficial impact on the success of the PD technique. Further long-term studies in larger patient groups are warranted to explore the potential of this promising new solution. 相似文献
7.
8.
9.
Hermonat PL Santin AD De Greve J De Rijcke M Bishop BM Han L Mane M Kokorina N 《Journal of human virology》1999,2(6):359-368
10.
Gottfried Greve Svein Rotevatn Ketil Grong Lodve Stangeland 《Virchows Archiv : an international journal of pathology》1988,413(3):205-213
Summary We have studied the histogenesis of malignant lymphoma (ML), small cleaved cell of the B-cell type and intermediate lymphocytic lymphoma (mantle zone lymphoma) by comparing immunophenotypes and ALP-activity of neoplastic cells with those of germinal center cells (follicular center cells) anti mantle zone (MZ) cells of secondary follicles in non-neoplastic lymphoid tissues. The neoplastic cells in 3 cases of ML, follicular, small cleaved cell and 1 case of ML, small cleaved cell expressed the phenotypes similar to those of germinal center (GC) B lymphocytes (SIgM+, B1+, B2+, CALLA+, SigD–, IL-2R–, Leu-1– and ALP–). The neoplastic cells in 2 cases of ML, follicular, small cleaved cell and 12 cases of ML, diffuse, small cleaved cell displayed the characteristic phenotypes of MZ B lymphocytes (SIgM+, SIgD+, BA-1+, IL-2R+, Leu-1+ and ALP+). The phenotypes of 2 cases of mantle zone lymphoma were closely comparable with those of MZ B lymphocytes. These findings indicate that the histogenesis of ML, small cleaved cell of the B-cell type is heterogeneous and can be divided phenotypically into 2 types (GC B lymphocyte origin and MZ B lymphocyte origin). It is also apparent that intermediate lymphocytic lymphoma (mantle zone lymphoma) is derived from MZ B lymphocytes of secondary follicles.This work was supported by a Grant-in-Aid for Cancer Research From the Ministry of Health and Welfare (NO. 61-2) 相似文献