全文获取类型
收费全文 | 4264篇 |
免费 | 173篇 |
国内免费 | 21篇 |
专业分类
耳鼻咽喉 | 160篇 |
儿科学 | 209篇 |
妇产科学 | 356篇 |
基础医学 | 297篇 |
口腔科学 | 179篇 |
临床医学 | 354篇 |
内科学 | 814篇 |
皮肤病学 | 65篇 |
神经病学 | 245篇 |
特种医学 | 219篇 |
外科学 | 831篇 |
综合类 | 72篇 |
一般理论 | 1篇 |
预防医学 | 107篇 |
眼科学 | 165篇 |
药学 | 191篇 |
中国医学 | 7篇 |
肿瘤学 | 186篇 |
出版年
2024年 | 1篇 |
2023年 | 40篇 |
2022年 | 59篇 |
2021年 | 96篇 |
2020年 | 53篇 |
2019年 | 86篇 |
2018年 | 97篇 |
2017年 | 83篇 |
2016年 | 120篇 |
2015年 | 126篇 |
2014年 | 158篇 |
2013年 | 227篇 |
2012年 | 274篇 |
2011年 | 306篇 |
2010年 | 165篇 |
2009年 | 154篇 |
2008年 | 328篇 |
2007年 | 362篇 |
2006年 | 342篇 |
2005年 | 360篇 |
2004年 | 299篇 |
2003年 | 243篇 |
2002年 | 182篇 |
2001年 | 96篇 |
2000年 | 58篇 |
1999年 | 53篇 |
1998年 | 13篇 |
1997年 | 12篇 |
1996年 | 4篇 |
1995年 | 6篇 |
1994年 | 2篇 |
1993年 | 2篇 |
1992年 | 9篇 |
1991年 | 5篇 |
1990年 | 5篇 |
1989年 | 8篇 |
1988年 | 8篇 |
1987年 | 4篇 |
1986年 | 1篇 |
1985年 | 4篇 |
1982年 | 2篇 |
1975年 | 1篇 |
1971年 | 1篇 |
1968年 | 1篇 |
1966年 | 2篇 |
排序方式: 共有4458条查询结果,搜索用时 0 毫秒
1.
F. Murina R. Felice S. Di Francesco L. Nelvastellio I. Cetin 《Gynecological endocrinology》2020,36(5):431-435
AbstractThis study is a single-center, retrospective analysis of postmenopausal women presenting with dyspareunia and vulvar pain, aiming to evaluate relative effectiveness of vestibular CO2 laser therapy as a treatment. Three monthly sessions of laser were performed to each patient and thereafter a three-months follow-up was stablished. A total number of 72 patients undergoing vestibular laser treatment were recruited from patient files in the period between 2016 and 2018. Among these, 39 women also received a concomitant treatment with ospemifene (60?mg/day) during the study period. There was a statistically significant reduction of all the symptoms in both groups up to the three month follow-up. Regarding dryness and dyspareunia, the relief tent to be more prominent in the ospemifene?+?laser group at all follow-ups and remained statistically significant at three-month follow-up. Specifically, vestibular dryness was significantly lower in the ospemifene?+?laser group compared with the laser treatment group (?87% vs???34%, respectively), and the vestibular health score started declining faster in the ospemifene?+?laser group. Although, additional research is needed to understand the mechanism of action, our data shows that a combination regimen of laser and ospemifene may improve clinical effectiveness for long-term treatment of symptoms associated with the under-recognized genitourinary syndrome of menopause. 相似文献
2.
3.
4.
Erkan Yildirim Erkan Kaptanoglu Kanat Ozisik Ethem Beskonakli Ozerk Okutan Mustafa F Sargon Kamer Kilinc Unal Sakinci 《European journal of cardio-thoracic surgery》2004,25(4):523-529
OBJECTIVE: We aimed to demonstrate the time-dependent ultrastructural changes in pneumocyte type II cells following brain injury, and to propose an electron microscopic scoring model for the damage. METHODS: Forty Wistar-Albino female rats weighing 170-200 g were used. The rats were allocated into five groups. The first group was the control and the second was the craniotomy without trauma. The others were trauma groups. Weight-drop method was used for achieving head trauma. Samples were obtained from the right and left pulmonary lobes at 2-, 8-, and 24-h intervals after transcardiac perfusion. An electron microscopic scoring model was used to reveal the changes. RESULTS: There were no ultrastructural pathological findings pointing to lung injury in any rat of the control groups. There was intense intracellular oedema in type II pneumocyte and interstitial oedema in the adjacent tissue in trauma groups. Oedema in mitochondria and dilatation in both smooth endoplasmic reticulum and Golgi apparatus was more evident in the 8- and 24-h trauma groups. The chromatin dispersion was disintegrated in the nucleus in all trauma groups. Scores of all trauma groups were significantly different from the controls (P<0.05). All trauma groups were different from each other at significant levels (P<0.05 for each trauma groups). CONCLUSIONS: The data suggested that ultrastructural damage is obvious at 2 h and deteriorates with time. The electron microscopic scoring model worked well in depicting the traumatic changes, which were supported by lipid peroxidation. Further experiments are needed to determine the exact outcome after brain death model. 相似文献
5.
Z. Bircan M. Soran I. Yildirim M. Doĝan A. Şahin A. Bilici M. Danaci 《International urology and nephrology》1997,29(3):357-361
Radius, ulna, short bones (RUS), carpal (CARP) bone age (BA), tibial corticodiaphyseal (C/D) ratio and trabecular aspect were
assessed in 19 children with steroid dependent nephrotic syndrome and 15 age matched healthy children. Both RUS and CARP BA
were significantly lower than in the controls. Trabecular aspect and tibial C/D ratio did not show any statistical significance.
There was a positive correlation between HSDS and RUS BA delay (r=−0.476, p<0.05); CARP BA delay and RUS BA delay (r=0.563,
p<0.01) and RUS BA and CARP BA (r=0.891, p<0.001). In conclusion, RUS and CARP BA are both retarded and positively correlated
in steroid dependent nephrotic children. 相似文献
6.
Kadir Baykal Sükrü Yildirim Haluk Inal Erdal Kalci Selami Albayrak Hakan Cingil Yavuz Önol 《International journal of urology》1997,4(1):104-105
Metastatic carcinoma to the testis is very rare. Metastasis of prostate adenocarcinoma to testis was detected incidentally after bilateral orchiectomy for hormonal management of metastatic prostate carcinoma. The metastatic lesion was not identified in physical examination or in macroscopic dissection of the testis after surgery. Microscopy revealed an adenocarcinoma which, given the history of the patient and a positive immunohistochemical stain for PSA, was identified as metastatic prostatic adenocarcinoma. 相似文献
7.
8.
Serkan Yildirim 《Hand surgery》2005,10(2-3):323-326
The author reports an unusual case of neural fibrolipoma (lipofibromatous hamartoma) of the ulnar nerve in the hand. A 20-year-old man presented with a fusiform soft tissue mass in his right hand. Neurological examination was normal except to minimal pain on palpation. Surgical exploration revealed that ulnar nerve and its digital branches were infiltrated by fibrofatty tissues. Fibrofatty tissues were dissected and removed from the nerve by microsurgical technique. Histological examination confirmed the diagnosis as a lipofibromatous hamartoma of the nerve. The result of surgical debulking was satisfactory. 相似文献
9.
10.
Gozde Erkanli Feriha Ercan Serap Sirvanci Emsal Salik Hasan Raci Yananli Filiz Onat Tangul San 《International journal of developmental neuroscience》2007,25(6):399-407
Five-day-old Wistar albino rats were injected with kainic acid (KA) or saline i.p. to investigate time-dependent alterations in morphology and number of basic fibroblast growth factor (bFGF) immunoreactive (-ir) astrocytes and neurons in hippocampus at 15, 30, and 90 days after the injections. Sections were stained with cresyl violet for morphological evaluation and bFGF immunohistochemistry was used for quantitative evaluation of bFGF-ir cell density. Fifteen days after KA injection, there was gliosis but no neuronal loss although disorganization in CA1, CA3, CA4 pyramidal layers and neuronal loss were evident 30 and 90 days after the injection. KA injected rats demonstrated significantly increased number of bFGF-ir astrocytes throughout the hippocampus and pyramidal neurons in CA2 after 15 days and decreased number of bFGF-ir cells after 30 and 90 days. The decrease in the number of bFGF-ir astroglia and neurons in long term after KA injection may indicate a decrease in the production of bFGF and/or number of bFGF-ir cells suggesting that protective effects of bFGF may be altered during epileptogenesis in hippocampus. 相似文献