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Zied Chaari Franois Montagne Matthieu Sarsam Benjamin Bottet Philippe Rinieri Andre Gillibert Jean Marc Baste 《Interactive Cardiovascular and Thoracic Surgery》2022,34(6):1016
Open in a separate window OBJECTIVESOur goal was to report our midterm results using imaging-assisted modalities with robotic segmentectomies for non-small-cell lung cancer (NSCLC).METHODSThis was a retrospective study of all robotic segmentectomies, with confirmed NSCLC, performed at our general and thoracic surgery unit in the Rouen University Hospital (France), from January 2012 through December 2019. Benign and metastatic lesions were excluded. Data were extracted from the EPITHOR French nationwide database.RESULTSA total of 121 robotic segmentectomies were performed for 118 patients with a median age of 65 (interquartile range: 60, 69) years. The majority had clinical stage T1aN0M0 (71.9%) or T1bN0M0 (13.2%). The mean (standard deviation) number of resected segments was 1.93 (1.09) with 80.2% imaging-assisted segmentectomies. Oriented (according to tumour location) or systematic lymphadenectomy or sampling was performed for 72.7%, 23.1% and 4.1% of patients. The postoperative course was uneventful for 94 patients (77.7%), whereas 34 complications occurred for 27 patients (22.3%), including 2 patients (1.7%) with Clavien-Dindo ≥III complications. The mean thoracic drainage duration was 4.12 days, and the median hospital stay was 4 days (interquartile range: 3, 5) after the operation. The 2-year survival rate was 93.9% (95% confidence interval: 86.4–97.8%). Excluding stage IV (n = 3) and stage 0 tumours (n = 6), the 2-year survival rate was 95.7% (95% confidence interval: 88.4–98.8%) compared to an expected survival rate of 94.0% according to stage-specific survival rates found in a large external reference cohort.CONCLUSIONSImaging-guided robotic-assisted thoracic surgery segmentectomy seems to be useful and oncological with good midterm results, especially for patients with early-stage NSCLC. 相似文献
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M. Eliezer G. Poillon A. Gillibert J. Horion Y. Cruypeninck E. Gerardin N. Magne A. Attyé 《Diagnostic and interventional imaging》2018,99(5):271-277
Purpose
To compare the degree of enhancement of the perilymph between two macrocyclic gadolinium-based contrast agents (gadobutrol and gadoterate meglumine) in patients with Meniere's disease at 3-T magnetic resonance imaging (MRI).Materials and methods
The MRI examinations of 20 patients with Meniere's disease obtained 4 hours after a single intravenous dose of macrocyclic gadolinium-based contrast agents were retrospectively compared. Ten patients (median age: 58.5 years; median body mass index [BMI]: 25) have received a single intravenous dose of gadoterate meglumine and 10 patients (median age: 45.5 years; median BMI: 25.4) have received a single-dose of gadobutrol. Two radiologists independently measured the signal intensity ratio (SIR) by using region of interest analysis and performed a visual assessment in order to evaluate the perilymph of each semicircular canal and of the vestibule.Results
No differences in SIR of the symptomatic ear were found between gadobutrol (median SIR: 1.58) and gadoterate meglumine (median SIR: 1.3) (P = 0.18). The SIR of the contralateral asymptomatic ear was significantly greater with gadobutrol (median: 1.62) than with gadoterate meglumine (median: 1.21) (P = 0.009). No differences in endolymphatic structures visualization were found between gadobutrol and gadoterate meglumine in the symptomatic ears (P = 0.27) but gadobutrol allowed a better assessment of endolymphatic structures and semicircular canals in the asymptomatic ear (P < 0.001).Conclusion
Gadobutrol and gadoterate meglumine provide similar degrees of enhancement of the symptomatic ear in patients with Meniere's disease but gadobutrol provides better anatomical details regarding endolymphatic space and semicircular canals of asymptomatic, contralateral ear. 相似文献4.
J. Seroussi C. Hautefort A. Gillibert R. Kania J.-P. Guichard H. Vitaux P. Herman E. Houdart A. Attyé M. Eliezer 《Diagnostic and interventional imaging》2018,99(11):679-687
Purpose
To report the postoperative magnetic resonance imaging (MRI) features after superior semicircular canal plugging in patients with Minor syndrome.Materials and methods
The MRI examinations with 3D T2-weighted SPACE sequence of 12 patients with superior semicircular canal dehiscence syndrome (SCDS) were retrospectively assessed. Two radiologists independently evaluated the presence of a filling defect of the superior semicircular canal above the superior ampulla and the common crus using an oblique plane parallel to the superior semicircular canal (Pöschl's plane).Results
Postoperative MRI showed a filling defect above the ampulla of the superior semicircular canal and the common crus in 8/12 patients (67%). Three patients (3/12; 25%) had a filling defect involving also the superior ampulla that caused postoperative labyrinthitis with labyrinthine enhancement on MRI in 2 patients. One patient (1/12; 8%) had incomplete plugging of superior semicircular canal with abnormal functional tests and remaining symptoms.Conclusion
Postoperative MRI shows a normal plugging aspect of the superior semicircular canal in 67% of patients. MRI can reveal complications that may have therapeutic implications. 相似文献5.
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Guillaume Gourcerol Jean Michel Gonzalez Bruno Bonaz Sébastien Fontaine Frank Zerbib Francois Mion Paul Basile André Gillibert Amélie Labonde Heithem Soliman Véronique Vitton Benoit Coffin Jérémie Jacques 《Neurogastroenterology and motility》2023,35(7):e14565
Background
Both gastric electrical stimulation (GES) and gastric-peroral endoscopic myotomy (G-POEM) can be offered to patients with gastroparesis and predominant nausea and vomiting. The study's aim was to compare GES and G-POEM efficacy on nausea and vomiting scores in patients with gastroparesis.Methods
Two multicenter cohorts of patients with medically refractory gastroparesis with predominant nausea and vomiting (defined as a score >2 on nausea and vomiting subscale that varied from 0 to 4) were treated either with GES (n = 34) or G-POEM (n = 30) and were followed for 24 months (M). Clinical response was defined as a decrease of ≥1 point in nausea and vomiting subscale without premature exclusion due to switch from one to the other technique before M24. Changes in symptomatic scales and quality of life were also monitored.Key Results
Patients from both groups were comparable although the mean score of nausea and vomiting subscale was higher in GES (3.0) compared to G-POEM group (2.6; p = 0.01). At M24, clinical response was achieved in 21/34 (61.7%) patients with GES and in 21/30 (70.0%; p = 0.60) patients with G-POEM. Mean scores of nausea and vomiting subscale decreased at M24 in both GES (from 3.0 to 1.6; p < 0.001) and G-POEM (from 2.6 to 1.2; p < 0.001) groups, although there was no difference between groups (difference adjusted from baseline: −0.28 [−0.77; 0.19]; p = 0.24). Likewise, symptomatic and quality of life scores improved at M24 in both groups, without difference according to treatment group.Conclusions and Inferences
At M24, we did not observe significant difference in efficacy of GES and G-POEM in medically refractory gastroparesis with predominant nausea and vomiting. 相似文献7.
Corentin Chaumont MD Nathanael Auquier MD Antoine Milhem MD Adrian Mirolo MD Alain Al Arnaout MD Elena Popescu MD Guillaume Viart MD Bénédicte Godin MD André Gillibert MD Arnaud Savouré MD Hélène Eltchaninoff MD PhD Frédéric Anselme MD PhD 《Journal of cardiovascular electrophysiology》2021,32(2):417-427
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M. Eliezer G. Poillon C. Maquet A. Gillibert J. Horion J.-P. Marie J.-P. Guichard N. Magne A. Attyé 《Diagnostic and interventional imaging》2019,100(5):259-268
Purpose
The purpose of this study was to assess whether the volume of the vestibular endolymphatic space correlates with the degree of hearing loss using heavily T2-weighted fast imaging employing steady-state acquisition with cycle phase (FIESTA-C) MRI.Materials and methods
A total of 23 patients with vestibular schwannoma, as diagnosed on typical image findings, who underwent FIESTA-C MRI were included. There were 13 women and 10 men with a mean age of 63.5 ± 9.3 (SD) years (range: 49–88 years). Two radiologists independently evaluated the volume of the utricle and saccule. Correlation between tumor volume, vestibular endolymphatic space volume and degree of hearing loss – as evaluated with the levels of pure-tone average and speech recognition threshold – were searched for.Results
The mean saccular, utricular and tumor volumes were 3.17 ± 1.1 (SD) mm3 (range: 1.45–5.7 mm3), 14.55 ± 5 (SD) mm3; (range: 6.6–23.9 mm3) and 17.4 ± 5.5 (SD) mm3; (range: 8.3–25.4 mm3), respectively. There was a moderate correlation between the volume of the utricle and the degree of hearing loss as evaluated with the levels of pure-tone average (rho = 0.5; P = 0.015) and speech recognition threshold (rho = 0.58; P = 0.004). There were no significant correlations between saccular and tumor volumes and the degree of hearing loss.Conclusion
The volume of the utricle in patients with obstructive vestibular schwannoma moderately correlates with the degree of hearing loss. 相似文献10.
Lamia Jelti Nadège Cordel André Gillibert Jean-Philippe Lacour Claire Uthurriague Marie-Sylvie Doutre Emmanuel Delaporte Sophie Duvert-Lehembre Gaelle Quereux Alain Dupuy Henri Adamski Christophe Bedane Laurent Misery Claire Abasq Thomas Camille Fleuret Philippe Bernard Guillaume Chaby Michel Dincan Pascal Joly 《The Journal of investigative dermatology》2019,139(2):469-473