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Eye rubbing-induced changes in intraocular pressure and corneal thickness measured at five locations, in subjects with ocular allergy 下载免费PDF全文
AIM: To assess the effects of eye rubbing on corneal thickness (CT) and intraocular pressure (IOP) measurements obtained 0-30min after habitual eye rubbing in symptomatic patients.
METHODS: Measurements of IOP and CT were obtained at five locations (central, temporal, superior, nasal and inferior) before, and every 5min for 30min interval after 30s of eye rubbing, for 25 randomly selected eyes of 14 subjects with ocular allergy and 11 age-matched normals. Differences in measurements were calculated in each group [Baseline measurements minus measurements recorded at each time interval after eye rubbing (for IOP), and for each corneal location (for CT)] and comparison were then made between groups (allergic versus control) for differences in any observed effects.
RESULTS: Within groups, baseline mean IOPs in the allergic patient-group (14.2±3.0 mm Hg) and in the control group (13.1±1.9 mm Hg) were similar at all times, after eye rubbing (P >0.05, for all). The maximum reduction in IOP was 0.8 mm Hg in the control subjects and the maximum increase was also 0.8 mm Hg in the allergic subjects. Between groups (allergic versus control), the changes in IOP remained under 1 mm Hg at all times (P=0.2) after 30min of eye rubbing. Between 0 and 30min of CT measurements after eye rubbing, the mean central CT (CCT), inferior CT (ICT), superior CT (SCT), temporal CT (TCT) and nasal CT (NCT) did not vary significantly from baseline values in the control and allergic-subject groups (P>0.05, for both). Between both groups, changes in CT were similar at all locations (P>0.05) except for the TC which was minimally thinner by about 4.4 μm (P=0.001) in the allergic subjects than in the control subjects, 30min following 30s of eye rubbing.
CONCLUSION: IOP measured in allergic subjects after 30s of habitual eye rubbing was comparable with that obtained in normal subjects at all times between 0 and 30min. Although, CT in the allergic subjects were similar to those of the control subjects at all times, it varied between +10 and -7.5 μm following eye rubbing, with the temporal cornea showing consistent reductions in thickness in the subjects with allergy. However, this reduction was minimal and was considered to not be clinically relevant. 相似文献
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Yu-Cheng Chou Rajashree Sarkar Ferdnand C. Osuagwu Jorge A. Lazareff 《Child's nervous system》2009,25(9):1111-1114
Object The object of this study was to present craniotomy for Chiari type I patients.
Materials and methods Six patients with Chiari type I underwent suboccipital craniotomy. All patients showed clinical improvement, and none had
any complications. Two patients had syringomyelia; it disappeared in entirety. We describe the procedure for posterior fossa
decompression.
Results Three-dimensional volumetric analysis using Vitrea workstation for postoperative posterior fossa volumes was calculated and
was seen to have been increased on an average, from pre-operative (168 cc) to postoperative volume (192 cc).
Conclusion We thus conclude that suboccipital craniotomy results in resolution of the Chiari symptoms yet achieves effective expansion
of posterior fossa. 相似文献
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Joanne Cox Research Registrar Christina S. Cotzias Research Registrar Obukohwo Siakpere Research Registrar Fiona I. Osuagwu Research Registrar Emma P. Holmes Clinical Research Co-ordinator Sara Paterson-Brown Consultant Obstetrician Gynaecologist 《BJOG : an international journal of obstetrics and gynaecology》1999,106(12):1280-1286
Objective To assess whether an inflatable obstetric belt, synchronised to apply uniform fundal pressure during a uterine contraction, reduces operative delivery rates when used in the second stage of labour.
Design Randomised controlled trial.
Methods Five hundred nulliparae with a singleton cephalic pregnancy at term and with an epidural in labour were recruited during the first stage and randomised at full dilatation. Standard care involved one hour passive second stage and one hour active pushing after which instrumental delivery was performed if delivery was not imminent. Those randomised to the belt group, in addition to standard care, had the inflatable obstetric belt for the whole second stage of labour.
Main outcome measure Mode of delivery.
Results One hundred and eleven of the 260 women in the belt group (42.7%) compared with 94 of the 240 in the control group (39.2%) had a spontaneous vertex delivery ( P = 0.423 ). The lift-out instrumental delivery rate was similar between the two groups: 108 belts (41.5%), compared with 101 controls (42.1%) ( P = 0.902 ), whereas rotational instrumental deliveries in the belt group were 26 belts (10%) compared with 36 controls (15%) ( P = 0.09 ). Fifteen women (5.8%) in the belt group and nine women (34%) in the control group had a caesarean section in the second stage ( P = 0.292 ). An intact perineum was more likely in the belt group (16.5% compared with 9–6%, P = 0.022 ) as was a third degree tear (6.5% compared with 0.4%, P = 0.001 ).
Conclusion The inflatable obstetric belt did not significantly reduce operative delivery rates when used in this clinical setting in the second stage of labour. 相似文献
Design Randomised controlled trial.
Methods Five hundred nulliparae with a singleton cephalic pregnancy at term and with an epidural in labour were recruited during the first stage and randomised at full dilatation. Standard care involved one hour passive second stage and one hour active pushing after which instrumental delivery was performed if delivery was not imminent. Those randomised to the belt group, in addition to standard care, had the inflatable obstetric belt for the whole second stage of labour.
Main outcome measure Mode of delivery.
Results One hundred and eleven of the 260 women in the belt group (42.7%) compared with 94 of the 240 in the control group (39.2%) had a spontaneous vertex delivery ( P = 0.423 ). The lift-out instrumental delivery rate was similar between the two groups: 108 belts (41.5%), compared with 101 controls (42.1%) ( P = 0.902 ), whereas rotational instrumental deliveries in the belt group were 26 belts (10%) compared with 36 controls (15%) ( P = 0.09 ). Fifteen women (5.8%) in the belt group and nine women (34%) in the control group had a caesarean section in the second stage ( P = 0.292 ). An intact perineum was more likely in the belt group (16.5% compared with 9–6%, P = 0.022 ) as was a third degree tear (6.5% compared with 0.4%, P = 0.001 ).
Conclusion The inflatable obstetric belt did not significantly reduce operative delivery rates when used in this clinical setting in the second stage of labour. 相似文献
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Visual rehabilitation in low-moderate keratoconus:intracorneal ring segment implantation followed by same-day topography-guided photorefractive keratectomy and collagen cross linking 下载免费PDF全文
AIM:To present the results of same-day topography-guided photorefractive keratectomy (TG-PRK) and corneal collagen crosslinking (CXL) after previous intrastromal corneal ring segment (ISCR) implantation for keratoconus.METHODS:An experimental clinical study on twenty-one eyes of 19 patients aged 27.1±6.6y (range 19-43y), with low to moderate keratoconus who were selected to undergo customized TG-PRK immediately followed by same-day CXL, 9mo after ISCR implantation in a university ophthalmology clinic. Refraction, uncorrected distance visual acuities (UDVA) and corrected distance visual acuities (CDVA), keratometry (K) values, central corneal thickness (CCT) and coma were assessed 3mo after TG-PRK and CXL.RESULTS:After TG-PRK/CXL:the mean UDVA (logMAR) improved significantly from 0.66±0.41 to 0.20±0.25 (P<0.05); Kflat value decreased from:48.44±3.66 D to 43.71±1.95 D; Ksteep value decreased from 45.61±2.40 D to 41.56±2.05 D; Kaverage also decreased from 47.00±2.66 D to 42.42±2.07 D (P<0.05 for all). The mean sphere and cylinder decreased significantly post-surgery from, -3.10±2.99 D to -0.11±0.93 D and from -3.68±1.53 to -1.11±0.75 D respectively, while the CDVA, CCT and coma showed no significant changes. Compared to post-ISCR, significant reductions (P<0.05 or all) in all K values, sphere and cylinder were observed after TG-PRK/CXL.CONCLUSION:Same-day combined topography-guided PRK and corneal crosslinking following placement of ISCR is a safe and potentially effective option in treating low-moderate keratoconus. It significantly improves all visual acuity, reduced keratometry, sphere and astigmatism, but causes no change in central corneal thickness and coma. 相似文献
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Ekure Edgar Ovenseri-Ogbomo Godwin Osuagwu Uchechukwu L. Agho Kingsley E. Ekpenyong Bernadine N. Ogbuehi Kelechi C. Ndep Antor O. Okonji Patrick Mashige Khathutshelo Percy Naidoo Kovin Shunmugan 《International journal of diabetes in developing countries.》2022,42(3):394-394
International Journal of Diabetes in Developing Countries - 相似文献
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Cox J Cotzias CS Siakpere O Osuagwu FI Holmes EP Paterson-Brown S 《British journal of obstetrics and gynaecology》1999,106(12):1280-1286
OBJECTIVE: To assess whether an inflatable obstetric belt, synchronised to apply uniform fundal pressure during a uterine contraction, reduces operative delivery rates when used in the second stage of labour. DESIGN: Randomised controlled trial. METHODS: Five hundred nulliparae with a singleton cephalic pregnancy at term and with an epidural in labour were recruited during the first stage and randomised at full dilatation. Standard care involved one hour passive second stage and one hour active pushing after which instrumental delivery was performed if delivery was not imminent. Those randomised to the belt group, in addition to standard care, had the inflatable obstetric belt for the whole second stage of labour. MAIN OUTCOME MEASURE: Mode of delivery. RESULTS: One hundred and eleven of the 260 women in the belt group (42.7%) compared with 94 of the 240 in the control group (39.2%) had a spontaneous vertex delivery (P = 0.423). The lift-out instrumental delivery rate was similar between the two groups: 108 belts (41.5%), compared with 101 controls (42.1%) (P = 0.902), whereas rotational instrumental deliveries in the belt group were 26 belts (10%) compared with 36 controls (15%) (P = 0.09). Fifteen women (5.8%) in the belt group and nine women (3.8%) in the control group had a caesarean section in the second stage (P = 0.292). An intact perineum was more likely in the belt group (16.5% compared with 9.6%, P = 0.022) as was a third degree tear (6.5% compared with 0.4%, P = 0.001). CONCLUSION: The inflatable obstetric belt did not significantly reduce operative delivery rates when used in this clinical setting in the second stage of labour. 相似文献