排序方式: 共有9条查询结果,搜索用时 15 毫秒
1
1.
Jacob Matthew Eckstein Nicole Nolan Erin Healy Chadwick Lewis Wright Angita Jain Christian Louis Barney Iman Washington Joseph Paul McElroy John Christopher Grecula Jessica Lynn Wobb Darrion Luther Mitchell Eric Miller Mauricio Gamez Dukagjin Blakaj Virginia Diavolitsis Aashish Bhatt 《Head & neck》2020,42(9):2405-2413
2.
Andrej D. Bitter Lampis C. Stavrinou Georgios Ntoulias Athanasios K. Petridis Morina Dukagjin Martin Scholz Werner Hassler 《Skull base》2013,74(2):97-102
Background Olfactory groove meningiomas remain surgically challenging. The common microsurgical approaches suffer from late exposure of the neurovascular structures. Conversely, the pterional approach has the advantage of early dissection of the posterior neurovascular complex.Methods We reviewed the records of patients treated for olfactory groove meningioma in our department between 1991 and 2010. A total of 61 patients underwent removal of olfactory groove meningiomas via the pterional approach. These included 58 primary and 3 recurrent tumors. Mean overall follow-up time was 122 months.Results Early exposure and dissection of the internal carotid artery, middle cerebral artery, anterior cerebral artery, and optic nerve was feasible in all cases. Complete tumor removal was achieved in 60 patients. Morbidity and mortality rates were 26% and 1.6% respectively. Postoperative complications included epileptic seizures (five patients) and cerebrospinal fluid (CSF) leak (two patients). During follow-up, we recorded three tumor recurrences.Conclusions The pterional approach appears to be an excellent solution for the treatment of olfactory groove meningiomas. Its foremost advantage is early visualization of the posterior neurovascular complex. Moreover, it allows frontal sinus preservation and timely tumor devascularization and avoids excessive brain retraction. The pterional view is familiar to most neurosurgeons and therefore the transition to this technique is fairly straightforward. 相似文献
3.
Palmer Joshua D. Perlow Haley K. Matsui Jennifer K. Ho Cindy Prasad Rahul N. Liu Kevin Upadhyay Rituraj Klamer Brett Wang Joshua Damante Mark Ghose Jayeeta Blakaj Dukagjin M. Beyer Sasha Grecula John Arnett Andrea Thomas Evan Chakravarti Arnab Lonser Russell Hardesty Douglas Prevedello Daniel Prabhu Roshan Elder James B. Raval Raju R. 《Journal of neuro-oncology》2022,159(2):389-395
Journal of Neuro-Oncology - The current standard of care for patients with a large brain metastasis and limited intracranial disease burden is surgical resection and post-operative single fraction... 相似文献
4.
Perlow Haley K. Yaney Alexander Yang Michael Klamer Brett Matsui Jennifer Raval Raju R. Blakaj Dukagjin M. Arnett Andrea Beyer Sasha Elder James B. Ammirati Mario Lonser Russell Hardesty Douglas Ong Shirley Giglio Pierre Pillainayagam Clement Goranovich Justin Grecula John Chakravarti Arnab Gondi Vinai Brown Paul D. Palmer Joshua D. 《Journal of neuro-oncology》2022,156(2):399-406
Journal of Neuro-Oncology - The standard of care for elderly glioblastoma patients is 40 Gy in 15 fraction radiotherapy with temozolomide (TMZ). However, this regimen has a lower biologic... 相似文献
5.
Palmer J. D. Gamez M. E. Ranta K. Ruiz-Garcia H. Peterson J. L. Blakaj D. M. Prevedello D. Carrau R. Mahajan A. Chaichana K. L. Trifiletti D. M. 《Journal of neuro-oncology》2020,148(3):445-454
Journal of Neuro-Oncology - Malignant gliomas have a dismal prognosis and significant efforts are being made to develop more effective treatments. Sonodynamic therapy (SDT) is an emerging modality... 相似文献
6.
7.
Thomas H. Beckham Christian Barney Erin Healy Adam R. Wolfe Andrew Branstetter Alexander Yaney Nadeem Riaz Sean M. McBride C. Jillian Tsai Julie Kang Yao Yu Linda Chen Eric Sherman Lara Dunn David G. Pfister Jeremy Tan Robert Rupert Marcelo Bonomi Zhigang Zhang Stephanie M. Lobaugh John C. Grecula Darrion L. Mitchell Jessica L. Wobb Eric D. Miller Dukagjin M. Blakaj Virginia M. Diavolitsis Nancy Lee Aashish D. Bhatt 《International journal of cancer. Journal international du cancer》2020,147(1):107-115
For patients ineligible for cisplatin with definitive radiotherapy (CP-CRT) for locally advanced head and neck squamous cell carcinoma (LA-HNSCC), concurrent cetuximab (C225-RT) is a popular substitute. Carboplatin-based chemoradiation (CB-CRT) is another option; however, relative efficacies of CP-CRT, CB-CRT and C225-RT are unclear, particularly in the human papillomavirus (HPV)-unrelated population. We identified 316 patients with stage III-IVB cancers of the oropharynx (24.7%), larynx (58.2%) and hypopharynx (17.1%) undergoing definitive C225-RT (N = 61), CB-CRT (N = 74) or CP-CRT (N = 181). Kaplan-Meier and cumulative incidence functions were generated to estimate overall survival (OS), locoregional failure (LRF) and distant metastasis (DM). Cox proportional hazards were used to determine the association of survival endpoints with clinical characteristics. Respectively, 3-year cumulative incidences for CP-CRT, CB-CRT and C225-RT were: LRF (0.19, 0.18 and 0.48, p ≤ 0.001), DM (0.17, 0.12 and 0.25, p = 0.32). Kaplan-Meier estimates for 3 year OS were: CP-CRT: 71%; CB-CRT: 59% and C225-RT: 54%; p = 0.0094. CP-CRT (hazard ratio [HR] 0.336; 95% confidence interval [CI] 0.203–0.557, p < 0.01) and CB-CRT (HR 0.279; 95% CI 0.141–0.551, p < 0.01) were associated with reduced hazard for LRF on multivariable analysis. CP-CRT (HR 0.548; 95% CI 0.355–0.845, p < 0.01) and CB-CRT (HR 0.549; 95% CI 0.334–0.904, p = 0.02) were associated with a reduced hazard for death on multivariable analysis. Propensity matching confirmed reduced hazards with a combined CP/CB-CRT group compared to C225-RT for LRF: HR 0.384 (p = 0.018) and OS: HR 0.557 (p = 0.045) and CB-CRT group compared to C225-RT for LRF: HR 0.427 (p = 0.023). In conclusion, CB-CRT is an effective alternative to CP-CRT in HPV-unrelated LA-HNSCC with superior locoregional control and OS compared to C225-RT. 相似文献
8.
9.
Sinonasal adenoid cystic carcinoma: Treatment outcomes and association with human papillomavirus
下载免费PDF全文
![点击此处可从《Head & neck》网站下载免费的PDF全文](/ch/ext_images/free.gif)
1