收费全文 | 5540篇 |
免费 | 318篇 |
国内免费 | 32篇 |
耳鼻咽喉 | 65篇 |
儿科学 | 403篇 |
妇产科学 | 98篇 |
基础医学 | 503篇 |
口腔科学 | 175篇 |
临床医学 | 368篇 |
内科学 | 1613篇 |
皮肤病学 | 87篇 |
神经病学 | 307篇 |
特种医学 | 135篇 |
外科学 | 819篇 |
综合类 | 91篇 |
一般理论 | 1篇 |
预防医学 | 188篇 |
眼科学 | 195篇 |
药学 | 480篇 |
中国医学 | 23篇 |
肿瘤学 | 339篇 |
2024年 | 6篇 |
2023年 | 51篇 |
2022年 | 89篇 |
2021年 | 209篇 |
2020年 | 140篇 |
2019年 | 204篇 |
2018年 | 264篇 |
2017年 | 150篇 |
2016年 | 224篇 |
2015年 | 188篇 |
2014年 | 276篇 |
2013年 | 303篇 |
2012年 | 473篇 |
2011年 | 464篇 |
2010年 | 279篇 |
2009年 | 220篇 |
2008年 | 345篇 |
2007年 | 355篇 |
2006年 | 360篇 |
2005年 | 262篇 |
2004年 | 257篇 |
2003年 | 194篇 |
2002年 | 178篇 |
2001年 | 51篇 |
2000年 | 44篇 |
1999年 | 33篇 |
1998年 | 30篇 |
1997年 | 13篇 |
1996年 | 20篇 |
1995年 | 19篇 |
1994年 | 14篇 |
1993年 | 9篇 |
1992年 | 22篇 |
1991年 | 11篇 |
1990年 | 6篇 |
1989年 | 16篇 |
1988年 | 10篇 |
1987年 | 10篇 |
1986年 | 7篇 |
1985年 | 4篇 |
1983年 | 7篇 |
1982年 | 3篇 |
1981年 | 16篇 |
1980年 | 8篇 |
1979年 | 4篇 |
1978年 | 9篇 |
1977年 | 6篇 |
1976年 | 5篇 |
1975年 | 4篇 |
1973年 | 4篇 |
Background
Despite significant pain relief following total hip arthroplasty (THA) in patients with ankylosing spondylitis, a small subset of patients presenting with extra-articular extension contracture of hips remains unsatisfied.Methods
We retrospectively evaluated the patients with ankylosing spondylitis who underwent simultaneous bilateral THA and had extensor tightness of both hips preoperatively. They were managed with modified Z-plasty of iliotibial band. Patients with windswept deformity, commonly seen in bilateral hip arthritis caused by ankylosing spondylitis, were excluded.Results
Between July 2011 and June 2015, out of 148 patients with bilateral hip involvement, 10 patients (20 hips) had extension contracture of both hips that was addressed during surgery. All patients were followed up for a minimum of 2 years. They could sit comfortably on a chair of height 18 inches with hips and knees flexed to at least 90°. The mean postoperative sum range of motion was 144.6° with an average hip flexion of 95° (range, 90°-105°). None of them had recurrence of extension contracture. There was significant improvement in range of motion and hence ambulation and function. No radiolucent lines exceeding 2 mm were seen in any of the zones around either of the components as evaluated in latest X-rays.Conclusion
Extension contracture of hip although rare is a noticeable problem and needs to be addressed during THA. Modified Z-plasty technique of iliotibial band is a reliable method in managing these patients. 相似文献Introduction
Severe acute respiratory syndrome coronavirus-2 has caused a pandemic of coronavirus disease (COVID-19) with many patients developing hypoxic respiratory failure. Corticosteroids reduce the time on mechanical ventilation, length of stay in the intensive care unit and potentially also mortality in similar patient populations. However, corticosteroids have undesirable effects, including longer time to viral clearance. Clinical equipoise on the use of corticosteroids for COVID-19 exists.Methods
The COVID STEROID trial is an international, randomised, stratified, blinded clinical trial. We will allocate 1000 adult patients with COVID-19 receiving ≥10 L/min of oxygen or on mechanical ventilation to intravenous hydrocortisone 200 mg daily vs placebo (0.9% saline) for 7 days. The primary outcome is days alive without life support (ie mechanical ventilation, circulatory support, and renal replacement therapy) at day 28. Secondary outcomes are serious adverse reactions at day 14; days alive without life support at day 90; days alive and out of hospital at day 90; all-cause mortality at day 28, day 90, and 1 year; and health-related quality of life at 1 year. We will conduct the statistical analyses according to this protocol, including interim analyses for every 250 patients followed for 28 days. The primary outcome will be compared using the Kryger Jensen and Lange test in the intention to treat population and reported as differences in means and medians with 95% confidence intervals.Discussion
The COVID STEROID trial will provide important evidence to guide the use of corticosteroids in COVID-19 and severe hypoxia.Objective: To quantify spatiotemporal and kinematic BW characteristics in post-stroke community ambulators and compare their performance to controls.
Methods: Individuals post-stroke (n = 15, 60.1 ± 12.9 years, forward speed: 1.13 ± 0.23 m/s) and healthy adults (n = 12, 61.2 ± 16.2 years, forward speed: 1.40 ± 0.13 m/s) performed forward walking (FW) and BW during a single session. Step characteristics and peak lower extremity joint angles were extracted using 3D motion analysis and analyzed with mixed-method ANOVAs (group, walking condition).
Results: The stroke group demonstrated greater reductions in speed, step length and cadence and a greater increase in double-support time during BW compared to FW (p < .01). Compared to FW, the post-stroke group demonstrated greater reductions in hip extension and knee flexion during BW (p < .05). The control group demonstrated decreased plantarflexion and increased dorsiflexion during BW, but these increases were attenuated in the post-stroke group (p < .05).
Conclusions: Assessment of BW can unmask post-stroke walking impairments not detected during typical FW. BW impairments may contribute to the mobility difficulties reported by adults post-stroke. Therefore, BW should be assessed when determining readiness for home and community ambulation. 相似文献