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Post‐introduction observation of transcatheter aortic valve implantation in Galicia (Spain) 下载免费PDF全文
Leonor Varela‐Lema DPharm PhD MPH Teresa Queiro‐Verdes MD PhD MPH José A. Baz‐Alonso MD José J. Cuenca‐Castillo MD PhD Darío Durán‐Muñoz MD PhD José R. Gónzalez‐Juanatey MD PhD FESC FACC José M. Herrera Noreña MD PhD Andrés Iñiguez‐Romo MD PhD FESC Diego López‐Otero MD PhD Gonzalo Pradas‐Montilla MD PhD José Rubio‐Álvarez MD PhD Jorge Salgado‐Fernández MD Ramiro Trillo Nouche MD Nicolás Vázquez‐González MD Marisa López‐García MD MS 《Journal of evaluation in clinical practice》2015,21(1):34-42
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Herpes zoster pain and postherpetic neuralgia (PHN) particularly affect older persons. This literature review presents how quality of life is evaluated and the consequences of shingles and PHN on the quality of life of older persons. Although more than 150 articles have been published on herpes zoster and its consequences, specific studies focusing on the older population are needed, in several domains like epidemiology, preventive medicine, neuropsychology, and pharmacology. 相似文献
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Adrian P. Harrison DPhil Steen H. Hansen DPharm Else M. Bartels DSc 《Pain practice》2012,12(8):620-625
Abstract: Pain treatment in ancient Greece, and through the middle ages in Europe, was to a great extent based on the expertise of the Greek physician Galen (c. 129–200 A.D.). Galen makes particular reference to “Olympic Victor’s Dark Ointment” (OVDO), which is listed with a number of collyria. Galen states that OVDO can be useful for treating extreme pain and swellings, forming one of the best eye salves. Olympic Victor’s Dark Ointment, an opium‐based treatment, forms a “patch” when applied externally as an ointment, because it quickly dries to cover a localized region but still retains its elastic properties. This study has recreated OVDO and applied the ointment to abdominal mouse skin, in vitro. To assess the efficacy of OVDO, the transdermal transfer of morphine was measured when given as OVDO and compared to morphine administered in the form of a solution of Opium + PBS (ringer). Olympic Victor’s Dark Ointment showed a transdermal transfer of morphine over time comparable to 25% of the most efficient modern transdermal opioid patches, while hardly any morphine was able to penetrate the skin when applied mixed in PBS. We conclude that OVDO is very efficient in its composition and may carry some forgotten abilities in terms of drug delivery, which could be transferred to modern medicine. Indeed, this may lead to a better choice of morphine use and controlled management in individual patient cases, taking both pain relief and anti‐inflammatory aspects into account. 相似文献
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Yo Kishimoto MD Shigeru Hirano MD PhD Yoshiharu Kitani MD Atsushi Suehiro MD Hiroo Umeda MD PhD Ichiro Tateya MD PhD Shin‐ichi Kanemaru MD PhD Yasuhiko Tabata PhD DMedSci DPharm Juichi Ito MD PhD 《The Laryngoscope》2010,120(1):108-113