全文获取类型
收费全文 | 2424篇 |
免费 | 128篇 |
国内免费 | 22篇 |
专业分类
耳鼻咽喉 | 25篇 |
儿科学 | 92篇 |
妇产科学 | 30篇 |
基础医学 | 386篇 |
口腔科学 | 218篇 |
临床医学 | 197篇 |
内科学 | 590篇 |
皮肤病学 | 89篇 |
神经病学 | 59篇 |
特种医学 | 168篇 |
外科学 | 232篇 |
综合类 | 22篇 |
一般理论 | 1篇 |
预防医学 | 204篇 |
眼科学 | 33篇 |
药学 | 113篇 |
中国医学 | 5篇 |
肿瘤学 | 110篇 |
出版年
2023年 | 15篇 |
2022年 | 46篇 |
2021年 | 60篇 |
2020年 | 50篇 |
2019年 | 58篇 |
2018年 | 71篇 |
2017年 | 49篇 |
2016年 | 49篇 |
2015年 | 78篇 |
2014年 | 108篇 |
2013年 | 110篇 |
2012年 | 187篇 |
2011年 | 176篇 |
2010年 | 122篇 |
2009年 | 91篇 |
2008年 | 127篇 |
2007年 | 84篇 |
2006年 | 96篇 |
2005年 | 90篇 |
2004年 | 72篇 |
2003年 | 77篇 |
2002年 | 61篇 |
2001年 | 51篇 |
2000年 | 37篇 |
1999年 | 40篇 |
1998年 | 49篇 |
1997年 | 53篇 |
1996年 | 49篇 |
1995年 | 40篇 |
1994年 | 24篇 |
1993年 | 25篇 |
1992年 | 17篇 |
1991年 | 23篇 |
1990年 | 15篇 |
1989年 | 26篇 |
1988年 | 33篇 |
1987年 | 29篇 |
1986年 | 34篇 |
1985年 | 18篇 |
1984年 | 10篇 |
1983年 | 10篇 |
1982年 | 11篇 |
1981年 | 14篇 |
1980年 | 7篇 |
1979年 | 9篇 |
1978年 | 10篇 |
1977年 | 11篇 |
1976年 | 6篇 |
1975年 | 10篇 |
1969年 | 9篇 |
排序方式: 共有2574条查询结果,搜索用时 0 毫秒
1.
2.
Anton A. Semenistyy Elena A. Litvina EA Anna G. Fedotova Chukwuweike Gwam Andrey N. Mironov 《Injury》2019,50(2):515-520
Background
Intramedullary nailing is considered a “gold standard” for treatment of tibial shaft fractures. However, some types of fractures are typically considered as “difficult for nailing”. This group includes the periarticular fractures, fractures of both bones at the same level, comminuted and segmental fractures of the tibia. Fixator-assisted nailing (FAN) is an effective method treatment of these types of fractures. The main requirements for the ideal reduction device are an ease of its installation and an ability of multiplanar fracture reduction. Fixator-assisted nailing (FAN) with the use of two perpendicular to each other monolateral tubular frames perfectly meets these requirements. In this study we present this new surgical technique and the analysis of first 30 cases.Methods
A prospective analysis was conducted for 30 patients with “difficult for nailing” tibial fractures treated with fixator-assisted nailing in our institution between September 1st, 2017, and March 1st, 2018. The duration of surgery and its different stages, the time of fluoroscopy, difficulties encountered during surgery, were analyzed. Clinical and radiological methods were used to evaluated reduction quality.Results
In all 30 cases the acceptable reduction was achieved. The mean duration of the surgical procedure was 73.7?±?3?min. The mean duration of fluoroscopy 85.9?±?4.8?s. In 7 cases we faced with technical difficulties, which were successfully addressed.Conclusion
The described technique of FAN is an effective method for the treatment of “difficult for nailing” tibial fractures. Future multi-centered studies with a larger number of patients are needed to validate our results. 相似文献3.
4.
5.
6.
7.
8.
Rui T Marinho Ruth M Pinto Maria L Santos Miguel Carneiro de Moura 《Liver international》2004,24(5):413-418
BACKGROUND: Seroreversion, negativation of anti-hepatitis C virus previously positive, is sometimes found in some chronic hepatitis C-sustained responders (SRs) to antiviral therapy. AIMS: To determine the probability of seroreversion in SR treatment with Interferon and Ribavirin, and lymphocyte T helper (CD4+) reactivity to HCV antigens. METHODS: Thirty SR were followed on average for 54.8 months. Anti-HCV was tested by third generation test. Peripheral blood mononuclear cells (PBMCs) were isolated from venous blood and cultured to evaluate CD4+ proliferation in response to 2 microg/ml of eight HCV recombinant antigens from core, NS3, NS4, NS5 regions. RESULTS: Seroreversion was verified in 23% of patients (7/30), appearing at 47.5+/-24.0 months. The probability of anti-HCV loss in this group was 25% at 56 months after ending therapy. In 57% (4/7), anti-HCV returned to positive. These 7 SR patients with seroreversion also showed weaker CD4+ reactivity in 5% of tests (3/56) than the remaining 23 anti-HCV-positive SRs who showed stronger reactivity in 18% of tests (33/184), P=0.036. CONCLUSIONS: One-quarter of the SR showed seroreversion of anti-HCV and weaker CD4+ specific HCV proliferation than those who remained anti-HCV positive. The data suggest that complete viral eradication is a possible and achievable clinical objective. 相似文献
9.
Antonio Vaz Carneiro 《Revista portuguesa de cardiologia》2004,23(12):1633-1638
The rationale behind screening for asymptomatic coronary artery disease is that it may diagnose advanced disease that, while frequently without symptoms, may present for the first time as sudden death. Identifying significant coronary artery disease would enable intervention against risk factors and, if necessary, preventive revascularization. The most recent evidence shows that screening for coronary artery disease with resting electrocardiogram, exercise tolerance testing or electron-beam computerized tomography in low-risk patients does more harm than good, and should not be performed. This negative recommendation is based on the fact that the use of the aforementioned tests has a negative benefit-harm ratio, because the false-positive rate cancels out any benefit from the occasional detection of real disease, inducing a cascade of further testing (sometimes with angiography) and overdiagnosis of a disease that is not in fact present, with negative psychological and financial consequences, such as increased insurance premiums. We feel that the Portuguese Society of Cardiology should intervene with the institutions performing screening of coronary heart disease in asymptomatic patients, and recommend abandoning a practice that is of little use and, overall, harmful. 相似文献
10.
Solitary bronchioloalveolar carcinoma: CT criteria 总被引:14,自引:0,他引:14
Kuhlman JE; Fishman EK; Kuhajda FP; Meziane MM; Khouri NF; Zerhouni EA; Siegelman SS 《Radiology》1988,167(2):379-382
The computed tomographic (CT) scans of 30 patients with solitary bronchioloalveolar carcinoma were reviewed. Common features at CT included the peripheral or subpleural location of a pulmonary mass (25 cases), pseudocavitation (18 cases), heterogeneous attenuation (17 cases), irregular margins forming a star pattern (22 cases), and pleural tags (21 cases). Using these CT criteria, four independent observers attempted to identify cases of bronchioloalveolar carcinoma from a larger sample of lung cancers and benign lesions by categorizing a series of test cases into four probability categories. Although the bronchioloalveolar carcinomas were correctly ranked in the two highest probability categories 75% of the time (in 45 of 60 cases), there was considerable overlap with other lung lesions, particularly with adenocarcinoma and large cell undifferentiated carcinoma. However, even though the typical features of bronchioloalveolar carcinoma are not invariable or highly specific, they are characteristic enough to suggest the diagnosis. 相似文献