全文获取类型
收费全文 | 797篇 |
免费 | 40篇 |
国内免费 | 41篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 29篇 |
妇产科学 | 7篇 |
基础医学 | 101篇 |
口腔科学 | 18篇 |
临床医学 | 81篇 |
内科学 | 244篇 |
皮肤病学 | 6篇 |
神经病学 | 12篇 |
特种医学 | 171篇 |
外科学 | 64篇 |
综合类 | 15篇 |
预防医学 | 14篇 |
眼科学 | 5篇 |
药学 | 59篇 |
肿瘤学 | 51篇 |
出版年
2023年 | 2篇 |
2022年 | 2篇 |
2021年 | 4篇 |
2020年 | 2篇 |
2019年 | 3篇 |
2018年 | 11篇 |
2017年 | 7篇 |
2016年 | 4篇 |
2015年 | 9篇 |
2014年 | 15篇 |
2013年 | 11篇 |
2012年 | 10篇 |
2011年 | 10篇 |
2010年 | 17篇 |
2009年 | 28篇 |
2008年 | 9篇 |
2007年 | 32篇 |
2006年 | 16篇 |
2005年 | 22篇 |
2004年 | 16篇 |
2003年 | 20篇 |
2002年 | 14篇 |
2001年 | 20篇 |
2000年 | 10篇 |
1999年 | 25篇 |
1998年 | 57篇 |
1997年 | 50篇 |
1996年 | 50篇 |
1995年 | 38篇 |
1994年 | 28篇 |
1993年 | 34篇 |
1992年 | 17篇 |
1991年 | 17篇 |
1990年 | 18篇 |
1989年 | 34篇 |
1988年 | 29篇 |
1987年 | 27篇 |
1986年 | 20篇 |
1985年 | 22篇 |
1984年 | 20篇 |
1983年 | 18篇 |
1982年 | 16篇 |
1981年 | 17篇 |
1980年 | 18篇 |
1979年 | 2篇 |
1978年 | 8篇 |
1977年 | 7篇 |
1976年 | 7篇 |
1975年 | 4篇 |
1973年 | 1篇 |
排序方式: 共有878条查询结果,搜索用时 31 毫秒
1.
2.
Arnold Criel Gregor Verhoef Robert Vlietinck Cristina Mecucci Johan Billiet Lucienne Michaux Peter Meeus ries Louwagie Angeline Van Orshoven Achiel Van Hoof Mark Boogaerts Herman Van den Berghe & Chris De Wolf-Peeters 《British journal of haematology》1997,97(2):383-391
We analysed a group of 390 patients, diagnosed with chronic lymphocytic leukaemia (CLL). Cases were subclassified as morphologically typical and atypical CLL according to the criteria of the FAB proposal. Typical CLL cases were mostly diagnosed at a low-risk stage (Binet A/Rai 0), required no immediate treatment and expected a long survival; atypical CLL cases mostly presented at a more advanced risk stage (Binet B/Rai I–II), usually required immediate treatment and their survival was shorter. Moreover, clinical staging was of prognostic significance in typical but not in atypical cases. In typical CLL, del(11q) was the most common chromosomal abnormality (21%) whereas in atypical CLL trisomy 12 was found in about 65% of the cases documented with an abnormal karyotype. Although chromosomal abnormalities were associated with a poor survival in typical CLL, they are of no prognostic significance in atypical CLL. Based on these data, we conclude that subtyping CLL by morphology enables the identification of two groups of cases, each characterized by a specific clinical presentation, different cytogenetic abnormalities and prognostic parameters. We speculate that these two groups may represent two related, but different, diseases with different prognostic parameters and a different survival. 相似文献
3.
4.
5.
Normal and diseased isolated lungs: high-resolution CT 总被引:8,自引:0,他引:8
6.
7.
The adhesion of hematopoietic progenitor cells to bone marrow stromal cells is critical to hematopoiesis and involves multiple effector molecules. Stromal cell molecules that participate in this interaction were sought by analyzing the detergent-soluble membrane proteins of GBI/6 stromal cells that could be adsorbed by intact FDCP-1 progenitor cells. A single-chain protein from GBI/6 cells having an apparent molecular weight of 37 Kd was selectively adsorbed by FDCP-1 cells. This protein, designated p37, could be surface-radiolabeled and thus appeared to be exposed on the cell membrane. An apparently identical 37- Kd protein was expressed by three stromal cell lines, by Swiss 3T3 fibroblastic cells, and by FDCP-1 and FDCP-2 progenitor cells. p37 was selectively adsorbed from membrane lysates by a variety of murine hematopoietic cells, including erythrocytes, but not by human erythrocytes. Binding of p37 to cells was calcium-dependent, and was not affected by inhibitors of the hematopoietic homing receptor or the cell-binding or heparin-binding functions of fibronectin. It is proposed that p37 may be a novel adhesive molecule expressed on the surface of a variety of hematopoietic cells that could participate in both homotypic and heterotypic interactions of stromal and progenitor cells. 相似文献
8.
9.
Van Hove JL Jaeken J Proesmans M Boeck KD Minner K Matthijs G Verbeken E Demunter A Boogaerts M 《American journal of medical genetics. Part A》2005,(2):152-158
Two siblings from a consanguineous family presented with a poikiloderma of limbs and face, plantar keratoderma, and toenail pachyonychia. Neutropenia and neutrophil dysfunction with impairment of the respiratory burst and bacterial killing resulted in frequent respiratory tract infections. A bronchocentric granulomatous pneumonia was a fatal complication. The clinical presentation is consistent with Clericuzio type poikiloderma with neutropenia. Literature review identified several additional probable patients. Genetic linkage analysis excluded the locus of the RECQL4 gene, mutations in which have been described in some patients with the Rothmund-Thomson poikiloderma syndrome. This report confirms the clinical and genetic identity of the Clericuzio type of poikiloderma with neutropenia syndrome. 相似文献
10.