全文获取类型
收费全文 | 4466篇 |
免费 | 324篇 |
国内免费 | 22篇 |
专业分类
耳鼻咽喉 | 36篇 |
儿科学 | 145篇 |
妇产科学 | 96篇 |
基础医学 | 696篇 |
口腔科学 | 76篇 |
临床医学 | 498篇 |
内科学 | 934篇 |
皮肤病学 | 147篇 |
神经病学 | 349篇 |
特种医学 | 131篇 |
外科学 | 413篇 |
综合类 | 20篇 |
一般理论 | 1篇 |
预防医学 | 430篇 |
眼科学 | 110篇 |
药学 | 268篇 |
中国医学 | 11篇 |
肿瘤学 | 451篇 |
出版年
2024年 | 7篇 |
2023年 | 46篇 |
2022年 | 93篇 |
2021年 | 150篇 |
2020年 | 102篇 |
2019年 | 151篇 |
2018年 | 125篇 |
2017年 | 107篇 |
2016年 | 119篇 |
2015年 | 127篇 |
2014年 | 168篇 |
2013年 | 237篇 |
2012年 | 337篇 |
2011年 | 337篇 |
2010年 | 175篇 |
2009年 | 150篇 |
2008年 | 278篇 |
2007年 | 236篇 |
2006年 | 256篇 |
2005年 | 269篇 |
2004年 | 228篇 |
2003年 | 216篇 |
2002年 | 210篇 |
2001年 | 55篇 |
2000年 | 40篇 |
1999年 | 65篇 |
1998年 | 45篇 |
1997年 | 35篇 |
1996年 | 34篇 |
1995年 | 30篇 |
1994年 | 19篇 |
1993年 | 18篇 |
1992年 | 23篇 |
1991年 | 18篇 |
1990年 | 18篇 |
1989年 | 16篇 |
1988年 | 23篇 |
1987年 | 20篇 |
1986年 | 14篇 |
1985年 | 12篇 |
1984年 | 15篇 |
1983年 | 12篇 |
1982年 | 13篇 |
1981年 | 19篇 |
1980年 | 15篇 |
1979年 | 15篇 |
1978年 | 10篇 |
1977年 | 8篇 |
1973年 | 6篇 |
1971年 | 9篇 |
排序方式: 共有4812条查询结果,搜索用时 15 毫秒
1.
2.
3.
Marital status and cohabitation during pregnancy: relationship with social conditions, antenatal care and pregnancy outcome in France 总被引:1,自引:0,他引:1
Summary. A survey of a representative sample of 5508 births in France in 1981 permitted the study of social characteristics of pregnant women, the medical care they received during their pregnancy and their pregnancy outcome, as a function of their marital status and whether or not they lived with the father of the child. Unmarried women living with the father (n = 412) like unmarried women living alone (n = 171), were more often younger, having their first baby and had a lower educational level than did married women living with the father (n = 4590). However, among the unmarried women, those living alone were in a more unfavourable position than those living with the father; in particular, they were more often less than 20 years old, had the minimum educational level required and were unemployed. Both groups of unmarried women had a higher preterm delivery rate than did married women, even after taking other risk factors into account in a logistic regression. The odds ratios (95% confidence interval) for pre-term delivery among unmarried mothers living without the father was 1.9 (1.0–3.4) and that for the unmarried cohabiting with the father was 1.6 (1.0–2.4). Thus, to fully appreciate the perinatal risks and medical needs during pregnancy, both the marital and cohabitational status of the women should be considered. 相似文献
4.
5.
Nephrotic syndrome in a mother and her infant: relationship with cytomegalovirus infection 总被引:1,自引:0,他引:1
Marisa Giani Alberto Edefonti Beatrice Damiani Giuseppina Marra Daniela Colombo Giovanni Banfi Emilio Rivolta Erich H. Strøm Michael Mihatsch 《Pediatric nephrology (Berlin, Germany)》1996,10(1):73-75
This case report describes infantile nephrotic syndrome (NS) in a baby girl with a clinically severe cytomegalovirus (CMV) infection. Culture of the baby's urine was positive for CMV and IgM anti-CMV antibodies were detected. After an unsuccessful course of corticosteroids, gancyclovir treatment was started and a remission of cutaneous, pulmonary, and renal symptoms was achieved. As the mother also developed NS at the end of pregnancy, a common etiology could be postulated, although there were no signs of recent CMV infection in the mother, only anti-CMV IgG. The relationship between CMV infection and glomerular disease is still unclear: NS may represent another manifestation of CMV disease. 相似文献
6.
E Damiani M T Cattaneo C Sessa E Zucca F Cavalli A Bertolini A Libretti R Beretta 《Tumori》1987,73(5):487-491
Urinary excretion of N-acetyl-beta-glucosaminidase (NAG) is an early marker of nephrotoxicity. NAG activity was assayed by the fluorimetric method of Leaback and Walker in 17 patients treated (22 courses) with carboplatin (CBDCA, 220-550 mg/m2) before infusion and 24, 48, 72 and 96 h after. Increased excretion of NAG, a sensitive index of renal tubular damage, was observed following 10 of the 22 courses. A transient increase in plasma creatinine and/or abnormal proteinuria was observed in 6 cases. Impaired renal function prior to therapy seems to be a predisposing factor to the nephrotoxicity. 相似文献
7.
D C Des Jarlais J Wenston S R Friedman J L Sotheran R Maslansky M Marmor S Yancovitz S Beatrice 《American journal of public health》1992,82(11):1531-1533
The Centers for Disease Control (CDC) has proposed revising the AIDS surveillance definition to include any HIV-seropositive person with a CD4 cell count of less than 200 cells per microliter. Based on a study of persons receiving treatment for HIV infection, this new definition would lead to an estimated 50% increase in the number of persons recognized as living with AIDS. Among 440 HIV-seropositive research subjects recruited from drug treatment programs and through street outreach in New York City, 59 met this definition, yet only 25% of those had been reported to the New York City AIDS registry. The new definition, if combined with HIV and T-cell testing at drug treatment and street outreach programs, could thus yield very large increases in the number of injecting drug users meeting the new surveillance definition of AIDS. 相似文献
8.
Actinomycetous infections typically involve either the head and neck or the extremities following a traumatic implantation.
Classic clinical associations are draining sinus tracts. This case report describes the pathologic and MR findings of a relatively
acute mycetomatous process involving the soft tissues. Pathologic findings in this case included an occasional granule composed
of gram positive, thin branching elements. These and other findings were consistent with actinomycetes bacterium infection.
The discussion centers around the use of MR, both with and without gadolinium, in evaluating this type of granulomatous infection.
Infiltration of the adjacent subcutaneous tissues was easier to appreciate on both the T1-weighted images without gadolinium
and the T1-weighted images with gadolinium when compared to the T2-weighted images. Signal characteristics as described in
this case report may suggest a granulomatous process. 相似文献
9.
Zvi Laron Jenny Frenkel lrit Gil-Ad Beatrice Klinger Ernesto Lubin Patrick Wuthrich François Boutignon Vincent Lengerts Romano Deghenghi 《Clinical endocrinology》1994,41(4):539-541
OBJECTIVE Hexarelin is a new synthetic growth hormone releasing peptide. We have tested the efficacy of intranasal (i.n.) administration of hexarelin to stimulate plasma GH and have compared this to the intravenous (i.v.) administration of the peptide. PATIENTS Ten children with familial short stature (FSS) aged 5·5-15·5 years and two known GH deficient patients aged 24 and 28 years without GH treatment. METHODS All 12 subjects were submitted to i.v. (1 μg/kg) and i.n. (20 μg/kg) hexarelin tests with a one-week interval between tests. Blood samples for GH, TSH, fT4 and T3 were obtained at 0, 15, 30, 60, 90 and 120 minutes. The hormone determinations were made by standard radio-immunoassays (RIA). RESULTS Both the i.n. and i.v. administration of hexarelin induced a large GH response, the mean (±SD) being 72·2± 35·5 mU/l for the i.n. test and 79·6 ± 53·0 mU/l for the i.v. test. The peak GH in the i.v. test occurred at 15–30 minutes and in the i.n. test between 30 and 60 minutes. The GH deficient patients showed no GH response In either test. Plasma TSH decreased in the FSS children from a mean (±SD) of 1.0 ± 0·26 to 0·64±0 2 mU/l (P<0 005) during the i.n. test and from 1·0±0·3 to 0·7±0·3mU/l (P> 0 05) during the I.v. test. In the isolated GH deficient patient, plasma TSH decreased from 1·06±0·38 mU/l to 0·86±0·17 during the i.v. test and from 1·60±0·01 to 1·11±0·06mU/l during the i.n. test. There were no significant changes in plasma fT4 or T3 in any of the tests. CONCLUSIONS The synthetic hexapeptide hexarelin is a potent pituitary GH stimulator when administered intra-nasally. The GH response was similar to that observed after intravenous hexarelin. Simultaneously, there was a significant decrease in plasma TSH but the concentrations remained in the normal range. These findings appear to be of theoretical and practical relevance to the investigation and management of short children. 相似文献
10.
R. Perniola M. L. Faneschi E. Manso M. Pizzolante A. Rizzo A. Sticchi Damiani R. Longo 《European journal of clinical microbiology & infectious diseases》2006,25(3):193-196
Reported here are the features of a Rhodotorula mucilaginosa outbreak that occurred in a neonatal intensive care unit. Over a period of 19 days, clinical and laboratory signs of sepsis appeared in four premature infants carrying indwelling vascular catheters. After bloodstream infection with R. mucilaginosa was ascertained, the patients underwent amphotericin B therapy and recovered completely. In a retrospective case-control study, the variables displaying a statistical difference between case and control-group neonates were birth weight, gestational age, duration of parenteral nutrition, duration of antibiotic therapy and prophylactic administration of fluconazole. To our knowledge, this is the first reported outbreak caused by yeasts of the Rhodotorula genus. 相似文献