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1.
K I Tareen A Bashir K Saeed T Hussain 《The Journal of international medical research》1988,16(3):204-209
A double-blind placebo-controlled study in children showed codergocrine mesylate to be effective in improving cognitive functions and behavioural symptoms associated with learning disorders. Forty randomly grouped children of either sex were given an increasing dosage of codergocrine mesylate and followed up for 12 weeks. A significant improvement was noted in speech (acquisition of new words, comprehensibility/meaningfulness of speech), sociability, attention/concentration, comprehension and memory. Improvement in behaviour (emotional lability and cooperativeness) was also noted. Problems of assessing cognitive progress in very young children with culturally appropriate methods were encountered. 相似文献
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The nutritive values of six traditional diets of the people of South‐Eastern Nigeria have been evaluated. A bioassay procedure was used; it involved the measurement of Biological Value, True Digestibility of the dietary nitrogen, Net Protein Utilization (operative) and Net Dietary Protein Calories Percent (NDpCals%). The procedures were applied to diets cooked as for human consumption, then dried and fed unmodified to male weaning albino rats. The results showed that in all cases the digestibility of the dietary nitrogen was high but the nutritive value was significantly low. These results are discussed and compared with the FAO recommended practical allowances for NDpCals% for various physiological ages and states. 相似文献
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Eli E. Machtei Georgios Romanos Philip Kang Suncica Travan Stephan Schmidt Evangelos Papathanasiou Nikolaos Tatarakis Moshik Tandlich Leila H. Liberman Jacob Horwitz Seyed Hossein Bassir Srinivas Myneni Harlan J. Shiau Lior Shapira Nikos Donos Athena Papas Joerg Meyle William V. Giannobile Panos N. Papapanou David M. Kim 《Journal of periodontology》2021,92(1):11-20
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Concrete strength and factors affecting its development during early concrete curing are important research topics. Avoiding uncertain incidents during construction and in service life of structures requires an appropriate monitoring system. Therefore, numerous techniques are used to monitor the health of a structure. This paper presents a nondestructive testing technique for monitoring the strength development of concrete at early curing ages. Dispersed carbon nanotubes (CNTs) were used with cementitious materials and piezoelectric (PZT) material, a PZT ceramic, owing to their properties of intra electromechanical effects and sensitivity to measure the electromechanical impedance (EMI) signatures and relevant properties related to concrete strength, such as the elastic modulus, displacement, acceleration, strength, and loading effects. Concrete compressive strength, hydration temperature, mixture ratio, and variation in data obtained from the impedance signatures using fuzzy logic were utilized in the comparative result prediction method for concrete strength. These results were calculated using a fuzzy logic-based model considering the maturity method, universal testing machine (UTM) data, and analyzed EMI data. In the study, for data acquisition, a hybrid PZT–CNT sensor and a temperature sensor (Smart Rock) were embedded in the concrete to obtain the hydration temperature history to utilize the concrete maturity method and provide data on the EMI signatures. The dynamic changes in the medium caused during the phase in the concrete strengthening process were analyzed to predict the strength development process of concrete at early curing ages. Because different parameters are considered while calculating the concrete strength, which is related to its mechanical properties, the proposed novel method considers that changes in the boundary condition occurring in the concrete paste modify the resonant frequency response of the structure. Thus, relating and analyzing this feature can help predict the concrete strength. A comprehensive comparison of the results calculated using the proposed module, maturity method, and cylindrical specimens tested using the UTM proved that it is a cost-effective and fast technique to estimate concrete strength to ensure a safe construction of reinforced cement concrete infrastructures. 相似文献
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Amirhossein Moghanian Roberto Portillo‐Lara Ehsan Shirzaei Sani Hailey Konisky Seyed Hossein Bassir Nasim Annabi 《Journal of tissue engineering and regenerative medicine》2020,14(1):66-81
Orthopedic surgical procedures based on the use of conventional biological graft tissues are often associated with serious post‐operative complications such as immune rejection, bacterial infection, and poor osseointegration. Bioresorbable bone graft substitutes have emerged as attractive alternatives to conventional strategies because they can mimic the composition and mechanical properties of the native bone. Among these, bioactive glasses (BGs) hold great potential to be used as biomaterials for bone tissue engineering owing to their biomimetic composition and high biocompatibility and osteoinductivity. Here, we report the development of a novel composite biomaterial for bone tissue engineering based on the incorporation of a modified strontium‐ and lithium‐doped 58S BG (i.e., BG‐5/5) into gelatin methacryloyl (GelMA) hydrogels. We characterized the physicochemical properties of the BG formulation via different analytical techniques. Composite hydrogels were then prepared by directly adding BG‐5/5 to the GelMA hydrogel precursor, followed by photocrosslinking of the polymeric network via visible light. We characterized the physical, mechanical, and adhesive properties of GelMA/BG‐5/5 composites, as well as their in vitro cytocompatibility and osteoinductivity. In addition, we evaluated the antimicrobial properties of these composites in vitro, using a strain of methicillin‐resistant Staphylococcus Aureus. GelMA/BG‐5/5 composites combined the functional characteristics of the inorganic BG component, with the biocompatibility, biodegradability, and biomimetic composition of the hydrogel network. This novel biomaterial could be used for developing osteoinductive scaffolds or implant surface coatings with intrinsic antimicrobial properties and higher therapeutic efficacy. 相似文献
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Mitchell JE Tareen B Sheehan W Agras S Brewerton TD Crow S Devlin M Eckert E Halmi K Herzog D Marcus M Powers P Stunkard A Walsh BT 《The International journal of eating disorders》2000,28(1):1-7
OBJECTIVE: This paper addresses the lack of a standard protocol for pharmacotherapy trials for patients with bulimia nervosa (BN) and anorexia nervosa (AN). METHOD: Twenty-two surveys were sent to established researchers in the field of eating disorders to elicit their opinions regarding medication trials, including baseline laboratory tests, the optimal length/frequency of medication management sessions, and the information that should or should not be included in these sessions. RESULTS: Sixteen of 22 researchers completed and returned the survey. Their answers are the basis of the data presented. DISCUSSION: We propose a battery of screening laboratory tests for both conditions. We suggest 30-45-min initial medication management sessions in both AN and BN trials with 15-min follow-ups to be held weekly for AN subjects, and weekly for 2 weeks, then biweekly for 2 weeks, then monthly, for BN subjects. We also recommend that published trials should include explicit details of medication management. 相似文献