全文获取类型
收费全文 | 521篇 |
免费 | 27篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 18篇 |
儿科学 | 16篇 |
妇产科学 | 9篇 |
基础医学 | 59篇 |
口腔科学 | 7篇 |
临床医学 | 24篇 |
内科学 | 80篇 |
皮肤病学 | 7篇 |
神经病学 | 28篇 |
特种医学 | 30篇 |
外科学 | 150篇 |
综合类 | 7篇 |
预防医学 | 40篇 |
眼科学 | 15篇 |
药学 | 31篇 |
中国医学 | 1篇 |
肿瘤学 | 27篇 |
出版年
2024年 | 3篇 |
2023年 | 4篇 |
2022年 | 26篇 |
2021年 | 15篇 |
2020年 | 5篇 |
2019年 | 7篇 |
2018年 | 26篇 |
2017年 | 3篇 |
2016年 | 17篇 |
2015年 | 12篇 |
2014年 | 10篇 |
2013年 | 25篇 |
2012年 | 38篇 |
2011年 | 44篇 |
2010年 | 22篇 |
2009年 | 31篇 |
2008年 | 24篇 |
2007年 | 35篇 |
2006年 | 29篇 |
2005年 | 27篇 |
2004年 | 19篇 |
2003年 | 35篇 |
2002年 | 25篇 |
2001年 | 12篇 |
2000年 | 6篇 |
1999年 | 10篇 |
1998年 | 2篇 |
1995年 | 2篇 |
1994年 | 3篇 |
1993年 | 1篇 |
1992年 | 3篇 |
1991年 | 1篇 |
1990年 | 2篇 |
1989年 | 3篇 |
1987年 | 1篇 |
1986年 | 2篇 |
1985年 | 1篇 |
1983年 | 1篇 |
1980年 | 2篇 |
1979年 | 1篇 |
1978年 | 1篇 |
1977年 | 3篇 |
1975年 | 1篇 |
1974年 | 3篇 |
1969年 | 2篇 |
1968年 | 3篇 |
1966年 | 1篇 |
排序方式: 共有549条查询结果,搜索用时 0 毫秒
1.
H Hachimi A Oudidi N Benmansour H Kadaoui Z Zaki M Ridal M N El Alami 《Tropical dental journal》2005,28(112):24-26
The cementoblastoma is a rare benign tumor of odontogen origin that interests the roots of the teeth especially the lower molars. The evolution is often silent, the radiological exam is not specific, the diagnosis of certainty is histological. The surgical treatment assures the recovery without aftermath. The authors report a case of cementoblastoma at a patient of 37 years for which he has benefited of a resection by vestibular way and debate diagnosis and therapeutic modes of this affection. 相似文献
2.
3.
4.
Usefulness of gram staining of blood collected from total parenteral nutrition catheter for rapid diagnosis of catheter-related sepsis. 总被引:4,自引:1,他引:4 下载免费PDF全文
F Moonens S el Alami A Van Gossum M J Struelens E Serruys 《Journal of clinical microbiology》1994,32(6):1578-1579
The accuracy of Gram staining of blood drawn from catheters used to administer total parenteral nutrition was compared with paired quantitative blood cultures for the diagnosis of catheter-related sepsis. Gram staining was positive in 11 of 18 episodes of catheter-related sepsis documented by quantitative culture (sensitivity, 61%) but in none of the 5 episodes of fever unrelated to catheter infection. Thus, this procedure enabled the rapid presumptive diagnosis and guidance of antimicrobial therapy for total parenteral nutrition catheter sepsis, with a positive predictive value of 100% and a negative predictive value of 42%. 相似文献
5.
6.
Muriel Moser Thibaut De Smedt Thierry Sornasse Franoise Tielemans Aziz Alami Chentoufi Eric Muraille Marcelle Van Mechelen Jacques Urbain Oberdan Leo 《European journal of immunology》1995,25(10):2818-2824
Exogenous glucocorticoid hormones are widely used as therapeutical agents, whereas endogenous glucocorticoids may act as physiological immunosuppressants involved in the control of immune and inflammatory responses. The optimal activation of T lymphocytes requires two distinct signals: the major histocompatibility complex-restricted presentation of the antigen and an additional co-stimulatory signal provided by the antigen-presenting cells. There is ample evidence that, among the cells able to present the antigen, the dendritic cells (DC) have the unique property to activate antigen-specific, naive T cells in vitro and in vivo, and are therefore required for the induction of primary immune responses. In this work, we tested whether glucocorticoids affected the capacity of DC to sensitize naive T cells. Our data show that, in vitro, the steroid hormone analog dexamethasone (Dex) affects the viability of DC, selectively downregulates the expression of co-stimulatory molecules on viable DC, and strongly reduces their immunostimulatory properties. In vivo, a single injection of Dex results in impaired antigen presenting function, a finding which correlates with reduced numbers of splenic DC. These results show that glucocorticoids regulate DC maturation and immune function in vitro and in vivo and suggest that this mechanism may play a role in preventing overstimulation of the immune system. 相似文献
7.
8.
Qaisar Abbas Pragati A. Shinde Mohammad Ali Abdelkareem Abdul Hai Alami Mojtaba Mirzaeian Arti Yadav Abdul Ghani Olabi 《Materials》2022,15(21)
Graphene is fundamentally a two-dimensional material with extraordinary optical, thermal, mechanical, and electrical characteristics. It has a versatile surface chemistry and large surface area. It is a carbon nanomaterial, which comprises sp2 hybridized carbon atoms placed in a hexagonal lattice with one-atom thickness, giving it a two-dimensional structure. A large number of synthesis techniques including epitaxial growth, liquid phase exfoliation, electrochemical exfoliation, mechanical exfoliation, and chemical vapor deposition are used for the synthesis of graphene. Graphene prepared using different techniques can have a number of benefits and deficiencies depending on its application. This study provides a summary of graphene preparation techniques and critically assesses the use of graphene, its derivates, and composites in environmental applications. These applications include the use of graphene as membrane material for the detoxication and purification of water, active material for gas sensing, heavy metal ions detection, and CO2 conversion. Furthermore, a trend analysis of both synthesis techniques and environmental applications of graphene has been performed by extracting and analyzing Scopus data from the past ten years. Finally, conclusions and outlook are provided to address the residual challenges related to the synthesis of the material and its use for environmental applications. 相似文献
9.
Farid Aassouani Oumayma Lahjouji Zakiya Ettilemsany Othman Chama Diallo Mamadou Nizar El Bouardi Meryem Haloua Mohammed fadl Tazi Abdelmalek Ousadden Moulay Youssef Alaoui Lamrani Meryem Boubbou Mustapha Maaroufi Badreeddine Alami 《Radiology Case Reports》2022,17(11):4199
Xanthogranulomatous pyelonephritis is a rare and aggressive form of chronic pyelonephritis, it can occur at all age groups but is more common in women than in men, supposedly relating to the increased incidence of urinary tract infections and chronic nephrolithiasis in woman. Computed tomography (CT) findings are very helpful in making the correct diagnosis, but the definitive diagnosis is still based on histology, as there are many differential diagnoses such as renal cell carcinoma and renal tuberculosis. The complications of this type of pyelonephritis are due to the involvement of adjacent organs. The most frequent ones are Psoas abscess, perinephric abscess, and sepsis. Nephrocutaneous and renocolic fistulas are less common. We report a case of a 61-year-old male, who presented to emergency for left-sided lumbar pain for whom radiological investigations confirmed a renocolic fistula complicating xanthogranulomatous pyelonephritis. The diagnosis of XGP was proven by histopathological examination of the nephrectomy specimen slides, but there was also association with an underlying malignant squamous differentiation consistent with urothelial carcinoma, which was not evident on CT. XGP is a rare variant of chronic pyelonephritis with known imaging features. The treatment of choice is nephrectomy and histopathological examination is required for final diagnosis, as there may be associated renal malignancy. 相似文献
10.
Meriem Haloua Nizar El Bouardi Mohamed Hbibi Badre Eddine Alami Youssef Alaoui Lamrani Mustapha Maaroufi Meryeme Boubbou 《Radiology Case Reports》2022,17(9):3015
Primary intracranial germ cell tumors are rare, often affecting children and young patients. Germinomas are the most common type of germ cell tumors. We present the case of a 10-year-old child, who was admitted with decreased visual acuity, asthenia, polyuro-polydipsic syndrome, and gait disorder. His biological assessment showed an hypocortisolemia and diabetes insipidus. Imaging found a bifocal process in the suprasellar and pineal region, suggestive of a bifocal germinoma. Imaging data and the positivity of human chorionic gonadotrophin in the cerebrospinal fluid were in favor of the diagnosis of bifocal germinal tumor confirmed by biopsy. Currently the patient is hospitalized in pediatric oncology department.The diagnosis of germ cell tumors is based on imaging, tumor marker assays, and biopsy. They are treated by radiation therapy alone or in combination with reduction chemotherapy, and surgery for tumor residues. The location of the tumor usually makes surgery difficult. 相似文献